Tracking the progression of the human inner cell mass during embryonic stem cell derivation (original) (raw)

• Han, D.W. et al. Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages. Cell 143, 617–627 (2010).
  Article CAS PubMed Google Scholar
• Hayashi, K., Lopes, S.M., Tang, F. & Surani, M.A. Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. Cell Stem Cell 3, 391–401 (2008).
  Article CAS PubMed Google Scholar
• Kuijk, E.W., Chuva de Sousa Lopes, S.M., Geijsen, N., Macklon, N. & Roeien, B.A. The different shades of mammalian pluripotent stem cells. Hum. Reprod. Update 17, 254–271 (2011).
  Article CAS PubMed Google Scholar
• Nichols, J. & Smith, A. Naive and primed pluripotent states. Cell Stem Cell 4, 487–492 (2009).
  Article CAS PubMed Google Scholar
• Nichols, J. & Smith, A. The origin and identity of embryonic stem cells. Development 138, 3–8 (2011).
  Article CAS PubMed Google Scholar
• Hanna, J. et al. Metastable pluripotent states in NOD-mouse-derived ESCs. Cell Stem Cell 4, 513–524 (2009).
  Article CAS PubMed PubMed Central Google Scholar
• Chen, A.E. et al. Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines. Cell Stem Cell 4, 103–106 (2009).
  Article CAS PubMed PubMed Central Google Scholar
• Brons, I.G. et al. Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 448, 191–195 (2007).
  Article CAS PubMed Google Scholar
• Tesar, P.J. et al. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448, 196–199 (2007).
  Article CAS PubMed Google Scholar
• Tang, F., Lao, K. & Surani, M.A. Development and applications of single-cell transcriptome analysis. Nat. Methods 8, S6–S11 (2011).
  Article CAS PubMed PubMed Central Google Scholar
• Najm, F.J. et al. Isolation of epiblast stem cells from preimplantation mouse embryos. Cell Stem Cell 8, 318–325 (2011).
  Article CAS PubMed PubMed Central Google Scholar
• Reijo Pera, R.A. et al. Gene expression profiles of human inner cell mass cells and embryonic stem cells. Differentiation 78, 18–23 (2009).
  Article PubMed Google Scholar
• O'Leary, T. et al. The influence of early embryo traits on human embryonic stem cell derivation efficiency. Stem Cells Dev. 785–793 (2011).
  Article PubMed Google Scholar
• Guo, G. et al. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev. Cell 18, 675–685 (2010).
  Article CAS PubMed Google Scholar
• Rathjen, J. et al. Formation of a primitive ectoderm like cell population, EPL cells, from ES cells in response to biologically derived factors. J. Cell Sci. 112, 601–612 (1999).
  CAS PubMed Google Scholar
• Hanna, L.A., Foreman, R.K., Tarasenko, I.A., Kessler, D.S. & Labosky, P.A. Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo. Genes Dev. 16, 2650–2661 (2002).
  Article CAS PubMed PubMed Central Google Scholar
• Tanaka, S.S. & Matsui, Y. Developmentally regulated expression of mil-1 and mil-2, mouse interferon-induced transmembrane protein like genes, during formation and differentiation of primordial germ cells. Mech. Dev. 119 (suppl. 1), S261–S267 (2002).
  Article PubMed Google Scholar
• Pelton, T.A., Sharma, S., Schulz, T.C., Rathjen, J. & Rathjen, P.D. Transient pluripotent cell populations during primitive ectoderm formation: correlation of in vivo and in vitro pluripotent cell development. J. Cell Sci. 115, 329–339 (2002).
  CAS PubMed Google Scholar
• Silva, S.S., Rowntree, R.K., Mekhoubad, S. & Lee, J.T. X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells. Proc. Natl. Acad. Sci. USA 105, 4820–4825 (2008).
  Article CAS PubMed PubMed Central Google Scholar
• Lengner, C.J. et al. Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell 141, 872–883 (2010).
  Article CAS PubMed Google Scholar
• Chuva de Sousa Lopes, S.M. et al. X chromosome activity in mouse XX primordial germ cells. PLoS Genet. 4, e30 (2008).
  Article PubMed PubMed Central Google Scholar
• Chazaud, C., Yamanaka, Y., Pawson, T. & Rossant, J. Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev. Cell 10, 615–624 (2006).
  Article CAS PubMed Google Scholar
• Vallier, L. et al. Activin/Nodal signalling maintains pluripotency by controlling Nanog expression. Development 136, 1339–1349 (2009).
  Article CAS PubMed PubMed Central Google Scholar
• Vallier, L. et al. Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways. PLoS ONE 4, e6082 (2009).
  Article PubMed PubMed Central Google Scholar
• James, D., Levine, A.J., Besser, D. & Hemmati-Brivanlou, A. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 132, 1273–1282 (2005).
  Article CAS PubMed Google Scholar
• Tam, P.P.L. & Loebel, D.A.F. Gene function in mouse embryogenesis: get set for gastrulation. Nat. Rev. Genet. 8, 368–381 (2007).
  Article CAS PubMed Google Scholar
• Dravid, G. et al. Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells 23, 1489–1501 (2005).
  Article CAS PubMed Google Scholar
• Sumi, T., Tsuneyoshi, N., Nakatsuji, N. & Suemori, H. Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling. Development 135, 2969–2979 (2008).
  Article CAS PubMed Google Scholar
• Hough, S.R., Laslett, A.L., Grimmond, S.B., Kolle, G. & Pera, M.F. A continuum of cell states spans pluripotency and lineage commitment in human embryonic stem cells. PLoS ONE 4, e7708 (2009).
  Article PubMed PubMed Central Google Scholar
• Chambers, I. et al. Nanog safeguards pluripotency and mediates germline development. Nature 450, 1230–1234 (2007).
  Article CAS PubMed Google Scholar
• Carson, D.D. et al. Embryo implantation. Dev. Biol. 223, 217–237 (2000).
  Article CAS PubMed Google Scholar
• Chuva de Sousa Lopes, S.M. & Roelen, B.A. On the formation of germ cells: The good, the bad and the ugly. Differentiation 79, 131–140 (2010).
  Article PubMed Google Scholar
• Chuva de Sousa Lopes, S.M. & Roelen, B.A. An overview on the diversity of cellular organelles during the germ cell cycle. Histol. Histopathol. 25, 267–276 (2010).
  Google Scholar
• Stephenson, E.L., Braude, P.R. & Mason, C. International community consensus standard for reporting derivation of human embryonic stem cell lines. Regen. Med. 2, 349–362 (2007).
  Article PubMed Google Scholar
• Solter, D. & Knowles, B.B. Immunosurgery of mouse blastocyst. Proc. Natl. Acad. Sci. USA 72, 5099–5102 (1975).
  Article CAS PubMed PubMed Central Google Scholar
• Strom, S. et al. Mechanical isolation of the inner cell mass is effective in derivation of new human embryonic stem cell lines. Hum. Reprod. 22, 3051–3058 (2007).
  Article PubMed Google Scholar
• Chuva de Sousa Lopes, S.M. et al. BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. Genes Dev. 18, 1838–1849 (2004).
  Article CAS Google Scholar
• Vandewoestyne, M. et al. Polar body mutation load analysis in a patient with A3243G tRNALeu(UUR) point mutation. Mitochondrion 11, 626–629 (2011).
  Article CAS PubMed Google Scholar
• Krenke, B.E. et al. Validation of a 16-locus fluorescent multiplex system. J. Forensic Sci. 47, 773–785 (2002).
  Article CAS PubMed Google Scholar
• Mukaida, T. et al. Vitrification of human blastocysts using cryoloops: clinical outcome of 223 cycles. Hum. Reprod. 18, 384–391 (2003).
  Article CAS PubMed Google Scholar
• Holm, S. A simple sequentially rejective multiple test procedure. Scand. J. Stat. 6, 65–70 (1979).
  Google Scholar