Binding proteins selected from combinatorial libraries of an α-helical bacterial receptor domain (original) (raw)

References

  1. Clackson, T. and Wells, J.A. 1994. In vitro selection from protein and peptide libraries. Trends Biotechnol. 12: 173–184.
    Article CAS Google Scholar
  2. Dunn, I.S. 1996. Phage display of proteins. Curr. Opin. Technol. 7: 547–553.
    CAS Google Scholar
  3. Pinilla, C., Appel, J., Blondelle, S., Dooley, C., Dorner, B., Eichksr, J. et al. 1995. A review of the utility of soluble peptide combinatorial libraries. Biopolymers. 37: 221–240.
    Article CAS Google Scholar
  4. Griffith, A.D., Williams, S.C., Hartley, O., Tomlinson, I.M., Waterhouse, P., Crosby, W.L. et al. 1994. Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J. 13: 3245–3260.
    Article Google Scholar
  5. Vaughn, T.J., Williams, A.J., Pritchard, K., Osbourn, J.K., Pope, A.R., Earnshaw, J.C. et al. 1996. Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library. Nature Biotechnology 14: 309–314.
    Article Google Scholar
  6. Bianchi, E., Folgori, A., Wallace, A., Ncotra, M., Acali, S., Phalipon, A. et al. 1995. A conformationally homogeneous combinatorial peptide library. J. Mol. Biol. 247: 154–160.
    Article CAS Google Scholar
  7. Ku, J. and Schultz, P.G. 1995. Alternate protein frameworks for molecular recognition. Proc. Natl. Acad. Sci. USA 92: 6552–6556.
    Article CAS Google Scholar
  8. McConnell, S. and Hoess, R.H. 1995. Tendamistat as a scaffold for conformationally constrained phage peptide libraries. J. Mol. Biol. 250: 460–470.
    Article CAS Google Scholar
  9. Martin, R., Toniatti, C., Salvatti, A.L., Ciliberto, G., Cortese, R. and Sollazzo, M. 1996. Coupling protein design and in vitro selection strategies: Improving specificity and affinity of a designed β-protein IL-6 antagonist. J. Mol. Biol. 255: 86–97.
    Article CAS Google Scholar
  10. Lu, Z., Murray, K.S., Van Cleave, V., LaVallie, E.R., Stahl, M.L. and McCoy, J.M. 1995. Expression of thtoredoxin random peptide libraries on the _Escherichia coll_cell surface as functional fusions to flagellin: a system designed for exploring protein-protein interactions. Bio/Technol. 13: 366–372.
    CAS Google Scholar
  11. Berkower, I. 1996. The promise and pitfalls of monoclonal antibody therapeutics. Curr. Opin. Biotechnol. 7: 622–628.
    Article CAS Google Scholar
  12. Moks, T., Abrahmsén, I., Nilsson, B., Hellman, U., Sjöquist, J. and Uhlén, M. 1986. Staphylococcal protein A consists of five IgG-binding domains. Eur. J. Biochem. 156: 637–643.
    Article CAS Google Scholar
  13. Ståhl, S. and Nygren, P. 1997. The use of gene fusions to protein A and protein G in immunology and biotechnology. Path. Biol. 45: 66–76.
    Google Scholar
  14. Samuelsson, E., Moks, T., Nilsson, B. and Uhlén, M. 1994. Enhanced in vitro refolding of insulin-liki growth factor I using a solubilizing fusion partner. Biochemistry 33: 4207–4211.
    Article CAS Google Scholar
  15. Samuelsson, E., Jonasson, P., Viklund, F., Nilsson, B. and Uhlén, M. 1996. Affinity-assisted in vivo folding of a secreted human peptide hormone in Escherichia coli. Nature Biotechnology 14: 751–755.
    Article CAS Google Scholar
  16. Olsson, A., Eliasson, L., Guss, B., Nilsson, B., Hellman, U., Lindberg, M. and Uhlén, M. 1987. Structure and evolution of the repetitive gene encoding strepto-coccal protein G. Eur. J. Biochem. 168: 319–324.
    Article CAS Google Scholar
  17. Alexander, P., Fahnestock, S., Lee, T., Orban, J. and Bryan, P. 1992. Thermodynamic analysis of the folding of the streptococcal protein G IgG-binding domains B1 and B2: why small proteins tend to have high denaturation temperatures. Biochemistry 31: 3597–3603.
    Article CAS Google Scholar
  18. Deisenhofer, J. 1981. Crystallographic refinement and atomic models of human Fc fragment and its complex with fragment B of protein A from _Staphylococcus aureus_at 2. 9- and 2.8-Å resolution. Biochemistry 20: 2361–2370.
    Article CAS Google Scholar
  19. Sauer-Eriksson, E.A., Kleywegt, G.J., Uhlén, M. and Jones, T.A. 1995. Crystal structure of the C2 fragment of streptococcal protein G in complex with the Fc domain of human IgG. Structure 3: 265–278.
    Article CAS Google Scholar
  20. Tashiro, M. and Montelione, G.T. 1995. Structures of bacterial immunoglobulin-binding domains and their complexes with immunoglobulins. Curr. Opin. Struct. Biol. 5: 471–481.
    Article CAS Google Scholar
  21. Kraulis, P.J., Jonasson, P., Nygren, P., Uhlén, M., Jendeberg, L., Nilsson, B. and Kördel, J. 1996. The serum albumin-binding domain of streptococcal protein G is a three-helical bundle: a heteronuclear NMR study. FEES Letters 378: 190–194.
    Article CAS Google Scholar
  22. Jendeberg, L., Persson, B., Andersson, R., Karlsson, R., Uhlén, M. and Nilsson, B. 1995. Kinetic analysis of the interaction between protein A domain variants and human Fc using plasmon resonance detection. J. Molec. Recogntt. 8: 270–278.
    Article CAS Google Scholar
  23. Jendeberg, L., Tashiro, M., Tejero, R., Lyons, B.A., Uhlén, M., Montelione, G.T. and Nilsson, B. 1996. The mechanism of binding Staphylococcal protein A to immunoglobin G does not involve helix unwinding. Biochemistry 35: 22–31.
    Article CAS Google Scholar
  24. Gouda, H., Torrigoe, H., Saito, A., Sato, M., Arata, Y. and Shimada, I. 1992. Three-dimensional solution structure of the domain B of Staphylococcal protein A: comparisons of the solution and crystal structures. Biochemistry. 31: 9665–9672.
    Article CAS Google Scholar
  25. Lyons, B.A., Tashiro, M., Cedergren, L., Nilsson, B. and Montelione, G. 1993. An improved strategy for determining resonance assignments for isotopically enriched proteins and its application to an engineered domain of Staphylococcal protein A. Biochemistry 32: 7839–7845.
    Article CAS Google Scholar
  26. Ståhl, S., Nygren, P., Sjölander, A. and Uhlén, M. 1993. Engineered bacterial receptors in immunology. Curr. Opin. Immunol. 5: 272–277.
    Article Google Scholar
  27. Nilsson, B., Moks, T., Jansson, B., Abrahmsén, L., Elmblad, A., Holmgren, E. et al. 1987. A synthetic IgG-binding domain based on Staphylococcal protein A. ProtEng. 1: 107–113.
    CAS Google Scholar
  28. Cedergren, L., Andersson, R., Jansson, B., Uhlén, M. and Nilsson, B. 1993. Mutational analysis of the interaction between Staphylococcal protein A and human IgG,. Prot. Eng. 6: 441–448.
    Article CAS Google Scholar
  29. Nord, K., Nilsson, J., Nilsson, B., Uhlén, M. and Nygren, P. 1995. A combinatorial library of an α-helical bacterial receptor domain. Prot. Eng. 8: 601–608.
    Article CAS Google Scholar
  30. Djojonegoro, B.M., Benedik, M.J. and Willson, R.C. 1994. Bacteriophage surface display of an immunoglobulin-binding domain of _Staphylococcus aureus_protein A. Bio/Technol. 12: 169–172.
    CAS Google Scholar
  31. Kushawaha, A., Chowdhury, P.S., Arora, K., Abrol, S. and Chaudhary, V.K. 1994. Construction and characterization of Mi3 bacteriophages displaying functional IgG-binding domains of Staphylococcal protein A. Gene 151: 45–51.
    Article Google Scholar
  32. Braisted, A.C. and Wells, J.A. 1996. Minimizing a binding domain from protein A. Proc. Natl. Acad. Sci. USA 93: 5688–5692.
    Article CAS Google Scholar
  33. Nilsson, J., Bosnes, M., Larsen, R., Nygren, P., Uhlén, M. and Lundeberg, J. 1997. Heat-mediated activation of affinity immobilized _Taq_DNA polymerase. Biotechniques 22: 744–751.
    Article CAS Google Scholar
  34. Calabresi, L., Vecchio, G., Longhi, R., Gianazza, E., Palm, G., Wadensten, H. et al. 1994. Molecular characterization of native and recomblnant apolipoprotein A-lmilano dimer. J. Biol.Chem. 269: 32168–32174.
    CAS PubMed Google Scholar
  35. Nilsson, J., Larsson, M., Ståhl, S., Nygren, P. and Uhlén, M. 1996. Multiple affinity domains for the detection, purification and immobilization of recombinant proteins. J. Molec. Recognit. 9: 585–594.
    Article CAS Google Scholar
  36. Richardson, J.H. and Marasco, W.A. 1995. Intracellular antibodies: development and therapeutic potential. Trends Biotechnol. 13: 306–310.
    Article CAS Google Scholar
  37. Cunningham, B.C., Lowe, D.G., Li, B., Bennett, B.D. and Wells, J. 1994. Production of an atrial natriuretic peptide variant that is specific for type a receptor. EMBO J. 13: 2508–2515.
    Article CAS Google Scholar
  38. Schier, R., Bye, J., Apell, G., McCall, A., Adams, G.P., Malmqvist, M. et al. 1996. Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection. J. Mol. Biol. 255: 28–33.
    Article CAS Google Scholar
  39. Nilsson, J., Nilsson, P., Witliams, Y., Petterson, L., Uhlén, M. and Nygren, P. 1994. Competitive elution of protein A fusion proteins allows specific recovery under mild conditions. Eur. J. Biochem. 224: 103–108.
    Article CAS Google Scholar
  40. Marks, J.D., Griffiths, A.D., Malmqvist, M., Clackson, T.P., Bye, J.M. and Winter, G. 1992. By-passing immunization: building high affinity human antibodies by chain shuffling. Bio/Technol. 10: 779–783.
    CAS Google Scholar
  41. Martin, F., Toniatti, C., Salvati, A.L., Venturini, S., Ciliberto, G., Cortese, R. and Sollazzo, M. 1994. The affinity-selection of a minibody polypeptide inhibitor of human interleukin-6. EMBO J. 13: 5303–5309.
    Article CAS Google Scholar
  42. Markland, W., Ley, C., Lee, S.W. and Ladner, R.C. 1996. Iterative optimization of high-affinity protease inhibitors using phage display. 1. Plasmin. Biochemistry 35: 8045–8057.
    Article CAS Google Scholar
  43. Markland, W., Ley, C. and Ladner, R.C. 1996. Iterative optimization of high-affinity protease inhibitors using phage display. 2.Plasma kallikrein and thrombin. Biochemistry 35: 8058–8067.
    Article CAS Google Scholar
  44. Holliger, P., Prospero, T. and Winter, G., 1993. “Diabodies”: small bivalent and bispecific antibody fragments. Proc. Natl. Acad. Sci. USA 90: 6444–6448.
    Article CAS Google Scholar
  45. Nygren, P.-Å, Flodby, P., Andersson, R., Wigzell, H. and Uhlén, M. 1991. In vivo stabilization of a human recombinant CD4 derivative by fusion to a serum-albumin-binding receptor, pp. 363–368 in Vaccines 97. Chanock, R.M., Ginsberg, H.S., Brown, F., and Lerner, R.A. (eds.) Cold Spring Harbor, Cold Spring, New York.
    Google Scholar
  46. Makrides, S., Nygren, P., Andrews, B., Ford, P., Evans, K.S., Hayman, E.G. et al. 1996. Extended in vivo half-life of human soluble complement receptor type I fused to serum albumin-binding receptor. J. Pharm. Exp. Therap. 277: 534–540.
    CAS Google Scholar
  47. Rüther, U. 1982. pUR 250 allows rapid chemical sequencing of both strands of inserts. Nucleic Acid Research 10: 5765–5772.
    Article Google Scholar
  48. Maurer, R., Meyer, B.J. and Ptashne, M. 1980. Gene regulation at the right operator (On) of bacteriophage lambda. —I. OR3 and autogenous negative control by represser. J. Mol. Biol. 139: 147–161.
    Article CAS Google Scholar
  49. Dower, W.J., Miller, J.F. and Ragsdale, C.W. 1988. High efficiency transformation of E. coli by high voltage electroporation. Nucleic Add Res. 16: 6127–6145.
    Article CAS Google Scholar
  50. Hultman, T., Ståhl, S., Homes, E. and Uhlén, M. 1989. Direct solid phase sequencing of genomic and plasmid DNA using magnetic beads as solid support. Nucleic Acids Res. 17: 4937–4946.
    Article CAS Google Scholar
  51. Gräslund, T., Nilsson, J., Lindberg, A.M., Uhlén, M. and Nygren, P.-Å 1997. Production of a thermostable DNA polymerase by site-specific cleavage of a heat-eluted affinity fusion protein. Protein Expression and Purification 9: 125–132.
    Article Google Scholar

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