From chromatin to cancer: a new histone lysine methyltransferase enters the mix (original) (raw)
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- Published: 01 August 2004
Nature Cell Biology volume 6, pages 685–687 (2004)Cite this article
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Disruption of post-translational modifications of histone proteins perturbs the proper pattern of gene expression and has the potential to result in diseases, such as cancer. A study implicating a new histone lysine methyltransferase in tumorigenesis further corroborates the emerging link between cancer and epigenetics.
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References
- Hamamoto, R. et al. Nature Cell Biol. 6, 731–740 (2004).
Article CAS PubMed Google Scholar - Sims, R.J., Nishioka, K. & Reinberg, D. Trends Genet. 19, 629–639 (2003).
Article CAS PubMed Google Scholar - Ng, H.H., Robert, F., Young, R.A. & Struhl, K. Mol. Cell 11, 709–719 (2003).
Article CAS PubMed Google Scholar - Wysocka, J., Myers, M.P., Laherty, C.D., Eisenman, R.N. & Herr, W. Genes Dev. 17, 896–911 (2003).
Article CAS PubMed Google Scholar - Kuzmichev, A., Nishioka, K., Erdjument-Bromage, H., Tempst, P. & Reinberg, D. Genes Dev. 16, 2893–2905 (2002).
Article CAS PubMed Google Scholar - Cao, R. et al. Science 298, 1039–1043 (2002).
Article CAS PubMed Google Scholar - Gottlieb, P.D. et al. Nature Genet. 31, 25–32 (2002).
Article CAS PubMed Google Scholar - Brand, T., Andree, B., Schneider, A., Buchberger, A. & Arnold, H.H. Mech. Dev. 64, 53–59 (1997).
Article CAS PubMed Google Scholar - Abate-Shen, C. Nature Rev. Cancer 2, 777–785 (2002).
Article CAS Google Scholar - Orlando, V. Cell 112, 599–606 (2003).
Article CAS PubMed Google Scholar - Ayton, P.M. & Cleary, M.L. Oncogene 20, 5695–5707 (2001).
Article CAS PubMed Google Scholar - Varambally, S. et al. Nature 419, 624–629 (2002).
Article CAS PubMed Google Scholar
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Authors and Affiliations
- Department of Biochemistry,
Robert J. Sims 3rd & Danny Reinberg - Department of Biochemistry, Howard Hughes Medical Institute, Robert Wood Johnson Medical School, Piscataway, 08854, NJ, USA
Robert J. Sims 3rd & Danny Reinberg
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- Robert J. Sims 3rd
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Sims, R., Reinberg, D. From chromatin to cancer: a new histone lysine methyltransferase enters the mix.Nat Cell Biol 6, 685–687 (2004). https://doi.org/10.1038/ncb0804-685
- Issue Date: 01 August 2004
- DOI: https://doi.org/10.1038/ncb0804-685