CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth (original) (raw)

• Craig, A.M. & Banker, G. Neuronal polarity. Annu. Rev. Neurosci. 17, 267–310 (1994).
  Article CAS Google Scholar
• Bradke, F. & Dotti, C.G. Establishment of neuronal polarity: lessons from cultured hippocampal neurons. Curr. Opin. Neurobiol. 10, 574–581 (2000).
  Article CAS Google Scholar
• Fukata, Y., Kimura, T. & Kaibuchi, K. Axon specification in hippocampal neurons. Neurosci. Res. 43, 305–315 (2002).
  Article CAS Google Scholar
• Goshima, Y., Nakamura, F., Strittmatter, P. & Strittmatter, S.M. Collapsin-induced growth-cone collapse mediated by an intracellular protein related to UNC-33. Nature 376, 509–514 (1995).
  Article CAS Google Scholar
• Wang, L.H. & Strittmatter, S.M. A family of rat CRMP genes is differentially expressed in the nervous system. J. Neurosci. 16, 6197–6207 (1996).
  Article CAS Google Scholar
• Inatome, R. et al. Identification of CRAM, a novel unc-33 gene family protein that associates with CRMP3 and protein-tyrosine kinase(s) in the developing rat brain. J. Biol. Chem. 275, 27291–27302 (2000).
  CAS PubMed Google Scholar
• Inagaki, N. et al. CRMP-2 induces axons in cultured hippocampal neurons. Nature Neurosci. 4, 781–782 (2001).
  Article CAS Google Scholar
• Fukata, Y. et al. CRMP-2 binds to tubulin heterodimers to promote microtubule assembly. Nature Cell Biol. 4, 583–591 (2002).
  Article CAS Google Scholar
• Uemura, T., Shepherd, S. Ackerman, L., Jan, L.Y. & Jan, Y.N. numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell 58, 349–360 (1989).
  Article CAS Google Scholar
• Rhyu, M.S., Jan, L.Y. & Jan, Y.N. Asymmetric distribution of Numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell 76, 477–491 (1994).
  Article CAS Google Scholar
• Lu, B., Jan, L. & Jan, Y.N. Control of cell division in the nervous system: symmetry and asymmetry. Annu. Rev. Neurosci. 23, 531–556 (2000).
  Article CAS Google Scholar
• Salcini, A.E. et al. Binding specificity and in vivo targets of the EH domain, a novel protein–protein interaction module. Genes Dev. 11, 2239–2249 (1997).
  Article CAS Google Scholar
• Santolini, E. et al. Numb is an endocytic protein. J. Cell Biol. 151, 1345–1352 (2000).
  Article CAS Google Scholar
• Berdnik, D., Török, T., González-Gaitán, M. & Knoblich, J.A. The endocytic protein α-adaptin is required for Numb-mediated asymmetric cell division in Drosophila. Dev. Cell 3, 221–231 (2002).
  Article CAS Google Scholar
• Owen, D.J. et al. A structural explanation for the binding of multiple ligands by the α-adaptin appendage domain. Cell 97, 805–815 (1999).
  Article CAS Google Scholar
• Parton, R.G., Simons, K. & Dotti, C.G. Axonal and dendritic endocytic pathways in cultured neurons. J. Cell Biol. 119, 123–137 (1992).
  Article CAS Google Scholar
• Burack, M.A., Silverman, M.A. & Banker, G. The role of selective transport in neuronal protein sorting. Neuron 26, 465–472 (2000).
  Article CAS Google Scholar
• Kamiguchi, H. et al. The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway. J. Neurosci. 18, 5311–5321 (1998).
  Article CAS Google Scholar
• Kamiguchi, H. & Lemmon, V. Recycling of the cell adhesion molecule L1 in axonal growth cones. J. Neurosci. 20, 3676–3686 (2000).
  Article CAS Google Scholar
• Kamiguchi, H. & Yoshihara, F. The role of endocytic L1 trafficking in polarized adhesion and migration of nerve growth cones. J. Neurosci. 21, 9194–9203 (2001).
  Article CAS Google Scholar
• Schaefer, A.W. et al. L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1. J. Cell Biol. 157, 1223–1232 (2002).
  Article CAS Google Scholar
• Mishra, S.K. et al. Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor. EMBO J. 21, 4915–4926 (2002).
  Article CAS Google Scholar
• Guo, M., Jan, L.Y. & Jan, Y.N. Control of daughter cell fates during asymmetric division: interaction of Numb and Notch. Neuron 17, 27–41 (1996).
  Article Google Scholar
• Roncarati, R. et al. The γ-secretase-generated intracellular domain of β-amyloid precursor protein binds Numb and inhibits Notch signaling. Proc. Natl Acad. Sci. USA 99, 7102–7107 (2002).
  Article CAS Google Scholar
• Calderwood, D.A. et al. Integrin β cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling. Proc. Natl Acad. Sci. USA 100, 2272–2277 (2003).
  Article CAS Google Scholar
• Castellani, V., Chedotal, A., Schachner, M., Faivre-Sarrailh, C. & Rougon, G. Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance. Neuron 27, 237–249 (2000).
  Article CAS Google Scholar
• Castellani, V., De Angelis, E., Kenwrick, S. & Rougon, G. Cis and trans interactions of L1 with neuropilin-1 control axonal responses to semaphorin 3A. EMBO J. 21, 6348–6357 (2002).
  Article CAS Google Scholar
• Arimura, N. et al. Phosphorylation of collapsin response mediator protein-2 by Rho-kinase. Evidence for two separate signaling pathways for growth cone collapse. J. Biol. Chem. 275, 23973–23980 (2000).
  Article CAS Google Scholar
• James, P., Halladay, J. & Craig, E.A. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144, 1425–1436 (1996).
  CAS PubMed PubMed Central Google Scholar
• Gu, Y., Hamajima, N. & Ihara, Y. Neurofibrillary tangle-associated collapsin response mediator protein-2 (CRMP-2) is highly phosphorylated on Thr-509, Ser-518, and Ser-522. Biochemistry 39, 4267–4275 (2000).
  Article CAS Google Scholar
• Lemmon, V., Farr, K.L. & Lagenaur, C. L1-mediated axon outgrowth occurs via a homophilic binding mechanism. Neuron 2, 1597–1603 (1989).
  Article CAS Google Scholar
• Matsuura, Y., Possee, R.D., Overton, H.A. & Bishop, D.H. Baculovirus expression vectors: the requirements for high level expression of proteins, including glycoproteins. J. Gen. Virol. 68, 1233–1250 (1987).
  Article CAS Google Scholar
• Elbashir, S.M. et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494–498 (2001).
  Article CAS Google Scholar
• Krichevsky, A.M. & Kosik, K.S. RNAi functions in cultured mammalian neurons. Proc. Natl Acad. Sci. USA 99, 11926–11929 (2002).
  Article CAS Google Scholar
• Dho, S.E., French, M.B., Woods, S.A. & McGlade, C.J. Characterization of four mammalian Numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain. J. Biol. Chem. 274, 33097–33104 (1999).
  Article CAS Google Scholar