Treatment with biologic therapies and the risk of cancer in patients with IBD (original) (raw)
Fiocchi C (1998) Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology115: 182–205 ArticleCAS Google Scholar
MacDonald TT and Monteleone G (2005) Immunity, inflammation, and allergy in the gut. Science307: 1920–1925 ArticleCAS Google Scholar
Knight DM et al. (1993) Construction and initial characterization of a mouse-human chimeric anti-TNF antibody. Mol Immunol30: 1443–1453 ArticleCAS Google Scholar
Hanauer SB (2003). Crohn's disease: step up or top down therapy. Best Pract Res Clin Gastroenterol17:131–137 Article Google Scholar
Hanauer SB (2005) Top-down versus step-up approaches to chronic inflammatory bowel disease: presumed innocent or presumed guilty. [Editorial] Nat Clin Pract Gastroenterol Hepatol2: 493 Article Google Scholar
Fiocchi C (2004) Closing fistulas in Crohn's disease—should the accent be on maintenance or safety? N Engl J Med350: 934–936 ArticleCAS Google Scholar
Munkholm P et al. (1993) Intestinal cancer risk and mortality in patients with Crohn's disease. Gastroenterology105: 1716–1723 ArticleCAS Google Scholar
van Dullemen HM et al. (1995) Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2). Gastroenterology109: 129–135 ArticleCAS Google Scholar
Targan SR et al. (1997) A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. N Engl J Med337: 1029–1035 ArticleCAS Google Scholar
Rutgeerts P et al. (1999) Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease. Gastroenterology117: 761–769 ArticleCAS Google Scholar
Present DH et al. (1999) Infliximab for the treatment of fistulas in patients with Crohn's disease. N Engl J Med340: 1398–1405 ArticleCAS Google Scholar
Hanauer SB et al. (2002) Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet359: 1541–1549 ArticleCAS Google Scholar
Rutgeerts P et al. (2004) Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease. Gastroenterology126: 402–413 ArticleCAS Google Scholar
Sands BE et al. (2004) Infliximab maintenance therapy for fistulizing Crohn's disease. N Engl J Med350: 876–885 ArticleCAS Google Scholar
Kinney T et al. (2003) Immunomodulators and “on demand” therapy with infliximab in Crohn's disease: clinical experience with 400 infusions. Am J Gastroenterol98: 608–612 CASPubMed Google Scholar
Colombel JF et al. (2004) The safety profile of infliximab in patients with Crohn's disease: the Mayo Clinic experience in 500 patients. Gastroenterology126: 19–31 ArticleCAS Google Scholar
Ljung et al. (2004) Infliximab in inflammatory bowel disease: clinical outcome in a population-based cohort from Stockholm County. Gut53: 849–853 ArticleCAS Google Scholar
Sandborn WJ and Loftus EV (2004) Balancing the risks and benefits of infliximab in the treatment of inflammatory bowel disease. Gut53: 780–782 ArticleCAS Google Scholar
Biancone L et al. (2006) Infliximab and newly diagnosed neoplasia in Crohn's disease: a multicentre matched pair study. Gut55: 228–233 ArticleCAS Google Scholar
Orlando A et al. (2005) Infliximab in the treatment of Crohn's disease: predictors of response in an Italian multicentric open study. Dig Liver Dis37: 577–583 ArticleCAS Google Scholar
Persson PG et al. (1994) Crohn's disease and cancer: a population-based cohort study. Gastroenterology107: 1675–1679 ArticleCAS Google Scholar
Bickston SJ et al. (1999) The relationship between infliximab treatment and lymphoma in Crohn's disease. Gastroenterology117: 1433–1437 ArticleCAS Google Scholar
Alcain G et al. (2003) Acute leukemia after infliximab therapy. Am J Gastroenterol98: 2577 Article Google Scholar
Losco A et al. (2004) Epstein-Barr virus-associated lymphoma in Crohn's disease. Inflamm Bowel Dis10: 425–429 Article Google Scholar
Bucher C et al. (2005) Biologics in inflammatory disease: infliximab associated risk of lymphoma development. Gut54: 732–733 ArticleCAS Google Scholar
Nicholson T et al. (2005) Crohn's colitis presenting with node-negative colon cancer and liver metastasis after therapy with infliximab: report of two cases. Dis Colon Rectum48: 1651–1655 Article Google Scholar
Al-Za'abi AM et al. (2005) Eruptive tufted angiomas in a patient with Crohn's disease. J Clin Pathol58: 214–216 ArticleCAS Google Scholar
Zagoni T et al. (2005) Carcinoma arising in enterocutan fistulae of Crohn's disease patients: description of two cases. Int J Colorectal Dis21: 461–464 Article Google Scholar
Peyrin-Biroulet L et al. (2006) Colon cancer after infliximab therapy for Crohn's disease in a young patient transplanted for primary sclerosing cholangitis. Gut101: 2664–2665 Google Scholar
Podolsky DK et al. (2006) A 71-year old woman with Crohns' disease and altered mental status. N Engl J Med354: 1178–1184 ArticleCAS Google Scholar
Lewis JD et al. (2001). Inflammatory bowel disease is not associated with an increased risk of lymphoma. Gastroenterology121: 1080–1087 ArticleCAS Google Scholar
Loftus VE and Sandborn W (2001) Lymphoma risk in inflammatory bowel disease: influences of referral bias and therapy. Gastroenterology121: 1239–1242 Article Google Scholar
Brown SL et al. (2002) Tumor necrosis factor antagonist therapy and lymphoma development: twenty-six cases reported to the Food and Drug Administration. Arthritis Rheum46: 3151–3158 ArticleCAS Google Scholar
Parsi MA and Lashner BA (2004) Safety of infliximab: primum non nocere. The safety profile of infliximab in patients with Crohn's disease: the Mayo Clinic experience in 500 patients. Inflamm Bowel Dis10: 486–487 Article Google Scholar
Rutgeerts P et al. (2006) Review article: infliximab therapy for inflammatory bowel disease—seven years on. Aliment Pharmacol Ther23: 451–463 ArticleCAS Google Scholar
Chang JT and Lichtenstein GR (2006) Drug insight: antagonists of tumor-necrosis factor-α in the treatment of inflammatory bowel disease. Nat Clin Pract Gastroenterol Hepatol3: 220–228 ArticleCAS Google Scholar
Lichtenstein GR et al. (2006) Serious infections and mortality in association with therapies for Crohn's disease: TREAT Registry. Clin Gastroenterol Hepatol4: 621–630 ArticleCAS Google Scholar
Siegel CA et al. (2006) Risk and benefits of infliximab for the treatment of Crohn's disease. Clin Gastroenterol Hepatol4: 1017–1024 ArticleCAS Google Scholar
Chey WY et al. (2001) Infliximab for patients with refractory ulcerative colitis. Inflamm Bowel Dis7 (Suppl): S30–S33 Article Google Scholar
Sands BE et al. (2001) Infliximab in the treatment of severe, steroid-refractory ulcerative colitis: a pilot study. Inflamm Bowel Dis7: 83–88 ArticleCAS Google Scholar
Kaser A et al. (2001) Infliximab in severe steroid-refractory ulcerative colitis: a pilot study. Wien Klin Wochenschr113: 930–933 CASPubMed Google Scholar
Kohn A et al. (2002) Anti-tumour necrosis factor alpha (infliximab) in the treatment of severe ulcerative colitis: result of an open study on 13 patients. Dig Liver Dis34: 626–630 ArticleCAS Google Scholar
Actis GC et al. (2002) Infliximab for treatment of steroid-refractory ulcerative colitis. Dig Liver Dis34: 631–634 ArticleCAS Google Scholar
Probert CSJ et al. (2003) Infliximab in moderately severe glucorticoid resistant ulcerative colitis: a randomised controlled trial. Gut52: 998–1002 ArticleCAS Google Scholar
Ochsenkuhn T et al. (2004) Infliximab for acute, not steroid-refractory ulcerative colitis: a randomized pilot study. Eur J Gastroenterol Hepatol16: 1167–1171 Article Google Scholar
Järnerot G et al. (2005) Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: a randomized, placebo-controlled study. Gastroenterology128: 1805–1811 Article Google Scholar
Rutgeerts P et al. (2005) Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med353: 2462–2476 ArticleCAS Google Scholar
Su C et al. (2002) Efficacy of anti-tumor necrosis factor therapy in patients with ulcerative colitis. Am J Gastroenterol97: 2577–2584 ArticleCAS Google Scholar
National Cancer Institute. Surveillance, Epidemiology, and End Results Database (SEER) program. SEER Incidence Crude Rates, 11 Registries, 1993–2001 [http://seer.cancer.gov/] (accessed 28 November 2006)
Szlosarek PW et al. (2006) Expression and regulation of tumour necrosis factor alpha in normal and malignant ovarian epithelium. Mol Cancer Ther5: 382–390 ArticleCAS Google Scholar
Germanidis G et al. (2005) Regression of inflammatory myofibroblastic tumour of the gastrointestinal tract under infliximab treatment. Dig Dis Sci50: 262–265 Article Google Scholar
Jatoi A et al. (2004) A pilot study on safety and pharmacokinetics of infliximab for the cancer anorexia/weight loss syndrome in non-small-cell lung cancer patients. Support Care Cancer12: 859–863 Article Google Scholar
Couriel D et al. (2004) Tumor necrosis factor-alpha blockade for the treatment for the treatment of acute GVHD. Blood104: 649–654 ArticleCAS Google Scholar
Stack WA et al. (1997) Randomised controlled trial of CDP571 antibody to tumour necrosis factor-alpha in Crohn's disease. Lancet349: 521–524 ArticleCAS Google Scholar
Sandborn WJ et al. (2001) An engineered human antibody to TNF (CDP571) for active Crohn's disease: a randomized double-blind placebo-controlled trial. Gastroenterology120: 1330–1338 ArticleCAS Google Scholar
Sandborn WJ et al. (2004) CDP571, a humanised monoclonal antibody to tumour necrosis factor alpha, for moderate to severe Crohn's disease: a randomised, double-blind, placebo-controlled trial. Gut53: 1485–1493 ArticleCAS Google Scholar
Feagan BG et al. (2005) A randomized, double-blind, placebo-controlled trial of CDP571, a humanized monoclonal antibody to tumour necrosis factor-alpha, in patients with corticosteroid-dependent Crohn's disease. Aliment Pharmacol Ther21: 373–384 ArticleCAS Google Scholar
Feagan BG et al. (2006) CDP571, a humanized monoclonal antibody to tumour necrosis factor-alpha, for steroid-dependent Crohn's disease: a randomized, double-blind, placebo-controlled trial. Aliment Pharmacol Ther23: 617–628 ArticleCAS Google Scholar
D'Haens G et al. (2001) Etanercept in the treatment of active refractory Crohn's disease: a single-center pilot study. Am J Gastroenterol96: 2564–2568 ArticleCAS Google Scholar
Sandborn WJ et al. (2001) Etanercept for active Crohn's disease: a randomized, double-blind placebo-controlled trial. Gastroenterology121: 1089–1094 Article Google Scholar
Rutgeerts P et al. (2003) Treatment of active Crohn's disease with onercept (recombinant human soluble p55 tumour necrosis factor receptor): results of a randomized, open-label, pilot study. Aliment Pharmacol Ther17: 185–192 ArticleCAS Google Scholar
Rutgeerts P et al. (2006) Onercept for moderate-severe Crohn's disease: a randomized, double-blind, placebo-controlled trial. Clin Gastroenterol Hepatol4: 888–893 ArticleCAS Google Scholar
Sandborn WJ et al. (2004) An open-label study of the human anti-TNF monoclonal antibody adalimumab in subjects with prior loss of response or intolerance to infliximab for Crohn's disease. Am J Gastroenterol99: 1984–1989 ArticleCAS Google Scholar
Youdim A et al. (2004) A pilot study of adalimumab in infliximab-allergic patients. Inflamm Bowel Dis10: 333–338 Article Google Scholar
Papadakis KA et al. (2005) Safety and efficacy of adalimumab (D2E7) in Crohn's disease patients with an attenuated response to infliximab. Am J Gastroenterol100: 75–79 ArticleCAS Google Scholar
Hanauer S et al. (2006) Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology130: 323–333 ArticleCAS Google Scholar
Winter TA et al. (2004) Intravenous CDP870, a PEGylated Fab' fragment of a humanized anti-tumor necrosis factor antibody, in patients with moderate-to severe Crohn's disease: an exploratory study. Aliment Pharmacol Ther20: 1337–1346 ArticleCAS Google Scholar
Schreiber S et al. (2005) A randomized, placebo-controlled trial of certulizumab pegol (CDP870) for treatment of Crohns' disease. Gastroenterology129: 807–818 ArticleCAS Google Scholar
Shen C et al. (2005) Adalimumab induces apoptosis of human monocytes: a comparative study with infliximab and etanercept. Aliment Pharmacol Ther21: 251–258 ArticleCAS Google Scholar
Scheinfeld N et al. (2004) A comprehensive review and evaluation of the side effects of the tumor necrosis factor alpha blockers etanercept, infliximab and adalimumab. J Dermatol Treat15: 280–294 ArticleCAS Google Scholar
Hanauer S (2004) Efficacy and safety of tumor necrosis factor antagonists in Crohn's disease: overview of randomized clinical studies. Rev Gastroenterol Disord4 (Suppl): S18–S24 PubMed Google Scholar
Bongartz T et al. (2006) Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA295: 2275–2285 ArticleCAS Google Scholar
Gordon FH et al. (2001) A randomized placebo-controlled trial of a humanized monoclonal antibody to α4 integrin in active Crohn's disease. Gastroenterology121: 268–274 ArticleCAS Google Scholar
Ghosh S et al. (2003) Natalizumab for active Crohn's disease. N Engl J Med348: 24–32 ArticleCAS Google Scholar
Sandborn WJ et al. (2005) Natalizumab induction and maintenance therapy for Crohn's disease. N Engl J Med353: 1912–1925 ArticleCAS Google Scholar