Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis (original) (raw)

References

  1. Bai, L. & Merchant, J.L. ZBP-89 promotes growth arrest through stabilization of p53. Mol. Cell. Biol. 21, 4670–4683 (2001).
    Article CAS Google Scholar
  2. Hasegawa, T., Takeuchi, A., Miyaishi, O., Isobe, K. & de Crombrugghe, B. Cloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genes. J. Biol. Chem. 272, 4915–4923 (1997).
    Article CAS Google Scholar
  3. Hasegawa, T., Xiao, H. & Isobe, K. Cloning of a GADD34-like gene that interacts with the zinc-finger transcription factor which binds to the p21(WAF) promoter. Biochem. Biophys. Res. Commun. 256, 249–254 (1999).
    Article CAS Google Scholar
  4. Bai, L. & Merchant, J.L. Transcription factor ZBP-89 cooperates with histone acetyltransferase p300 during butylate activation of p21(waf1) transcription in human cells. J. Biol. Chem. 275, 30725–30733 (2000).
    Article CAS Google Scholar
  5. Rosai, J. (ed.) Male reproductive system, atrophy and infertility. in Ackerman's Surgical Pathology 1260–1265 (Mosby, St. Louis, 1996).
    Google Scholar
  6. Wong, T.W., Straus, F.H. & Warner, N.E. Testicular biopsy in the study of male infertility. I. Testicular cause of infertility. Arch. Pathol. 95, 151–159 (1973).
    CAS Google Scholar
  7. Nagy, A. et al. Embryonic stem cells alone are able to support fetal development in the mouse. Development 110, 815–821 (1990).
    CAS Google Scholar
  8. Matsui, Y., Zsebo, K. & Hogan, B.L. Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture. Cell 70, 841–847 (1992).
    Article CAS Google Scholar
  9. Yoshinaga, K., Muramatsu, H. & Muramatsu, T. Immunohistochemical localization of the carbohydrate antigen 4C9 in the mouse embryo: a reliable marker of mouse primordial germ cells. Differentiation 48, 75–82 (1991).
    Article CAS Google Scholar
  10. Momand, J., Zambetti, G.P., Olson, D.C., George, D. & Levine, A.J. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69, 1237–1245 (1992).
    Article CAS Google Scholar
  11. Thut, C.J., Goodrich, J.A. & Tjian, R. Repression of p53-mediated transcription by MDM2: a dual mechanism. Genes Dev. 11, 1974–1986 (1997).
    Article CAS Google Scholar
  12. Donehower, L.A. et al. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors. Nature 356, 215–221 (1992).
    Article CAS Google Scholar
  13. Rotter, V. et al. Mice with reduced levels of p53 protein exhibit the testicular giant-cell degenerative syndrome. Proc. Natl. Acad. Sci. USA 90, 9075–9079 (1993).
    Article CAS Google Scholar
  14. Barlow, C. et al. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell 86, 159–171 (1996).
    Article CAS Google Scholar
  15. Banin, S. et al. Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281, 1674–1677 (1998).
    Article CAS Google Scholar
  16. Xu, Y. et al. Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. Genes Dev. 10, 2411–2422 (1996).
    Article CAS Google Scholar
  17. Barlow, C. et al. Atm deficiency results in severe meiotic disruption as early as leptonema of prophase I. Development 125, 4007–4017 (1998).
    CAS Google Scholar
  18. McMahon, A.P. & Bradley, A. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 62, 1073–1085 (1990).
    Article CAS Google Scholar
  19. Wang, Z.Q., Kiefer, F., Urbánek, P. & Wagner, E.F. Generation of completely embryonic stem cell-derived mutant mice using tetraploid blastocyst injection. Mech. Dev. 62, 137–145 (1997).
    Article CAS Google Scholar
  20. Zambrowicz, B.P. et al. Disruption of overlapping transcripts in the ROSA βgeo 26 gene trap strain leads to widespread expression of β-galactosidase in mouse embryos and hematopoietic cells. Proc. Natl. Acad. Sci. USA 94, 3789–3794 (1997).
    Article CAS Google Scholar
  21. Hogan, B., Beddington, R., Costantini, F. & Lacy, E. (eds.) Techniques for visualizing genes, gene products, and specialized cell types. in Manipulating the Mouse Embryo 373–375 (Cold Spring Harbor Laboratory Press, Plainview, New York, 1994).
    Google Scholar
  22. Takeuchi, A. et al. Microglial NO induces delayed neuronal death following acute injury in the striatum. Eur. J. Neurosci. 10, 1613–1620 (1998).
    Article CAS Google Scholar
  23. Buehr, M. & McLaren, A. Isolation and culture of primordial germ cells. Methods Enzymol. 225, 58–77 (1993).
    Article CAS Google Scholar
  24. Wang, Y., Kobori, J.A. & Hood, L. The htβ gene encodes a novel CACCC box-binding protein that regulates T-cell receptor gene expression. Mol. Cell. Biol. 13, 5691–5701 (1993).
    Article CAS Google Scholar
  25. Taniuchi, T., Mortensen, E.R., Ferguson, A., Greenson, J. & Merchant, J.L. Overexpression of ZBP-89, a zinc finger DNA binding protein, in gastric cancer. Biochem. Biophys. Res. Commun. 233, 154–160 (1997).
    Article CAS Google Scholar

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