Long–term hepatic adenovirus–mediated gene expression in mice following CTLA4Ig administration (original) (raw)

• Kay, M.A. & Woo, S.L.C. Gene therapy for metabolic disorders. Trends Genet. 10, 253–257 (1994).
  Article CAS Google Scholar
• Li, Q., Kay, M.A., Finegold, M., Stratford-Perricaudet, L.D. & Woo, S.L.C. Assessment of recombinant adenoviral vectors for hepatic gene therapy. Hum. Gene Ther. 4, 403–408 (1993).
  Article CAS Google Scholar
• Kay, M.A. et al. In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs. Proc. natn. Acad. Sci. U.S.A. 91, 2353–2357 (1994).
  Article CAS Google Scholar
• Ishibashi, S. et al. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J Clin. Invest. 92, 883–893 (1993).
  Article CAS Google Scholar
• Kozarsky, K.F. et al. In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses. J. biol. Chem. 269, 13695–13702 (1994).
  CAS Google Scholar
• Yang, Y. et al. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc. natn. Acad. Sci. U.S.A. 91, 4407–4411 (1994).
  Article CAS Google Scholar
• Yang, Y., Ertl, H.C.J. & Wilson, J.M. MHC class l-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses. Immunity 1, 433–442 (1994).
  Article CAS Google Scholar
• Smith, T.A. et al. Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice. Nature Genet. 5, 397–402 (1993).
  Article CAS Google Scholar
• Barr, D. et al. Strain related variations in adenovirally mediated transgene expression in mouse hepatocytes in vivo: comparisons between immunocompetent and immunodeficient inbred strains. Gene Ther. 2, 151–155 (1995).
  CAS PubMed Google Scholar
• Englehardt, J.F., Ye, X., Doranz, B. & Wilson, J.M. Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver. Proc. natn. Acad. Sci. U.S.A. 91, 6196–6200 (1994).
  Article Google Scholar
• Hathcock, K.S. et al. Identification of an alternative CTLA4 ligand costimulatory for T cell activation. Science 262, 905–907 (1993).
  Article CAS Google Scholar
• Azuma, M. et al. B70 antigen is a second ligand for CTLA-4 and CD28. Nature 366, 76–79 (1993).
  Article CAS Google Scholar
• Linsley, P.S. & Ledbetter, J.A. The role of the CD28 receptor during T cell responses to antigen. A. Rev. Immunol. 11, 191–212 (1993).
  Article CAS Google Scholar
• Freeman, G. et al. Cloning of B7-2: a CTLA4 counter-receptor that costimulates human T cell proliferation. Science 262, 909–911 (1993).
  Article CAS Google Scholar
• Lin, H. et al. Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4lg plus donor-specific transfusion. J. exp. Med. 178, 1801–1806 (1993).
  Article CAS Google Scholar
• Lenschow, D.J. et al. Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg. Science 257, 789–792.
  Article CAS Google Scholar
• Finck, B.K., Linsley, P.S. & Wofsy, D. Treatment of murine lupus with CTLA4lg. Science 265, 1225–1227 (1994).
  Article CAS Google Scholar
• Kay, M.A., Graham, F., Leland, F. & Woo, S.L.C. Therapeutic serum concentrations of serum alpha 1-antitrypsin after adenoviral-mediated gene transfer to mouse hepatocytes in vivo. Hepatology 21, 815–819 (1995).
  CAS PubMed Google Scholar
• Kay, M.A. et al. Hepatic gene therapy: persistent expression of human alpha 1-antitrypsin in mice after direct gene delivery in vivo. Hum. Gene Ther. 3, 641–647 (1992).
  Article CAS Google Scholar
• Ponder, K.P. et al. Mouse heptocytes migrate to liver parenchyma and function indefinetely after intrasplenic transplantation. Proc. natn. Acad. Sci. U.S.A. 88, 1217–1221 (1991).
  Article CAS Google Scholar
• Dai, Y. et al. Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: Tolerization of factor IX and vector antigens allows for long-term expression. Proc. natn. Acad. Sci. U.S.A. 92, 1401–1405 (1995).
  Article CAS Google Scholar
• Rinaldo, C.R. & Torpey, D.J. III. Cell-mediated immunity and immunosuppression in herpes simplex virus infection. Immunodeficiency 5, 33–90 (1993).
  PubMed Google Scholar
• Simmons, A. & Tscharke, D.C. Anti-CD8 impairs clearance of herpes simplex virus from the nervous system: implications for the fate of virally infected neurons. J. exp. Med. 175, 1337–1244 (1992).
  Article CAS Google Scholar
• Shahinan, A. et al. Differential T cell costimulatory requirements in CD28-deficient mice. Science 261, 609–612 (1993).
  Article Google Scholar
• Bluestone, J.A. New perspectives of CD28-B7-mediated T cell costimulation. Immunity 2, 555–559 (1995).
  Article CAS Google Scholar
• Nonoyama, S., Smith, F.O., Bernstein, I.D. & Ochs, H.D. Strain dependent leakiness of mice with severe combined immune deficiency. J. Immunol. 150, 3817–3824 (1993).
  CAS PubMed Google Scholar
• Nonoyama, S., Hollenbaugh, D., Aruffo, A., Ledbetter, J.A. & Ochs, H.D. B cell activation via CD40 is required for specific antibody production by antigen stimulated human B cells. J. exp. Med. 178, 1097–1102 (1993).
  Article CAS Google Scholar
• Paul, W.A. & Seder, W.E. Lymphocyte responses and cytokines. Cell 76, 241–251 (1994).
  Article CAS Google Scholar
• Nguyen, L., Knipe, D.M. & Finberg, R.W. Mechanism of virus-induced Ig subclass shifts. J. Immunol. 152, 478–484 (1994).
  CAS PubMed Google Scholar
• Scaria, A., Curiel, D. & Kay, M.A. Complementation of a human adenovirus early region 4 deletion mutant in 293 cells using adenovirus-polylysine-DNA complexes. Gene Ther. 2, 295–298 (1995).
  CAS PubMed Google Scholar
• Rawle, F.C. et al. Specificity of the mouse cytotoxic T lymphocytes response to adenovirus 5. J. Immunol 146, 3977–3984 (1991).
  CAS PubMed Google Scholar
• Knodell, R.G. et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1, 431–435 (1981).
  Article CAS Google Scholar
• Lewis, D.B. et al. Interleukin 4 expressed in situ selectively alters thymocyte development J. exp. Med. 173, 89–100 (1994).
  Article Google Scholar