A possible vulnerability locus for bipolar affective disorder on chromosome 21q22.3 (original) (raw)
Egeland, J.A. et al. Bipolar affective disorder linked to DNA markers on chromosome 11. Nature325, 783–787 (1987). ArticleCASPubMed Google Scholar
Baron, M. Is there a gene for manic-depressive illness on the long arm of the X-chromosome? in Genetic approaches to mental disorders(eds Gershon, E.S. & Cloninger, C.R.) 253–272 (American Psychiatric Press, Washington, DC, 1994). Google Scholar
Kelsoe, J.R. et al. Revaluation of the linkage relationship between chromosome 11 p loci and the gene for bipolar affective disorder in the Old Order Amish. Nature342, 238–243 (1989). ArticleCASPubMed Google Scholar
Baron, M. et al. Diminished support for linkage between manic depressive illness and X-chromosome markers in three Israeli pedigrees. Nature Genet.3, 49–65 (1993). ArticleCASPubMed Google Scholar
Baron, M., Endicott, J. & Ott, J. Genetic linkage in mental illness: Limitations and prospects. Brit. J. Psychiat.157, 645–655 (1990). ArticleCASPubMed Google Scholar
O'Donovan, M.C. & Owen, M.J. Advances and retreats in the molecular genetics of major mental illness. Ann. Med.24, 171–177 (1992). ArticleCASPubMed Google Scholar
St George-Hyslop, P.H. et al. Genetic linakge studies suggest that Alzheimer's disease is not a single homogeneous disorder. Nature347, 194–197 (1990). ArticleCASPubMed Google Scholar
Pericak-Vance, M.A. et al. Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage. Am. J. hum. Genet.48, 1034–1050 (1991). CASPubMedPubMed Central Google Scholar
Schellenberg, G.D. et al. Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14. Science258, 668–671 (1992). ArticleCASPubMed Google Scholar
Risch, N. Assessing the role of HLA-linked and unlinked determinants of disease. Am. J. hum. Genet.40, 1–14 (1987). CASPubMedPubMed Central Google Scholar
Easton, D.F. Linkage analysis and genetic models for type I diabetes mellitus. Genet. Epidemiol.6, 83–88 (1989). ArticleCASPubMed Google Scholar
Owerbach, D. & Gabbay, K.H. Linkage of the VNTR/Insulin-gene and type I diabetes mellitus: increased gene sharing in affected sibling pairs. Am. J. hum. Genet.54, 909–912 (1994). CASPubMedPubMed Central Google Scholar
Hall, J.M. et al. Linkage of early-onset familial breast cancer to chromosome 17q21. Science250, 1684–1689 (1990). ArticleCASPubMed Google Scholar
Baron, M. et al. A pedigree series for mapping disease genes in bipolar affective disorder: sampling, assessment and analytic considerations. Psychiat Genet.4, 43–56 (1994). ArticleCAS Google Scholar
Delabar, J.-M. et al. Report on the Fourth International Workshop on Human Chromosome 21. Genomics18, 735–745 (1993). ArticleCASPubMed Google Scholar
NIH/CEPH Collaborative Mapping Group. A comprehensive genetic linkage map of the human genome. Science258, 67–86 (1992).
Hodge, S.E. & Greenberg, D.A. Sensitivity of lod scores to changes in diagnostic status. Amer. J. hum. Genet.50, 1053–1066 (1992). CASPubMedPubMed Central Google Scholar
Weeks, D.E. & Lange, K. A multilocus extension of the affected-pedigree-member method of linkage analysis. Am. J. hum. Genet.50, 859–868 (1992). CASPubMedPubMed Central Google Scholar
Ott, J. Strategies for characterizing highly polymorphic markers in human gene mapping. Am. J. hum. Genet.51, 283–290 (1992). CASPubMedPubMed Central Google Scholar
Babron, M.-C. et al. Linkage detection by the affected — pedigree — member method: what is really tested?. Genet. Epidemiol.10, 389–394 (1993). ArticleCASPubMed Google Scholar
Risch, N. & Giuffra, L. Model misspecification and multipoint linkage analysis. Hum. Hered.42, 77–92 (1992). ArticleCASPubMed Google Scholar
Vieland, V.J., Hodge, S.E. & Greenberg, D.A., Adequacy of single-locus approximations for linkage analyses of oligogenic traits. Genet. Epidemiol.9, 45–59 (1992). ArticleCASPubMed Google Scholar
Chumakov, I. et al. Continuum of overlapping clones spanning the entire human chromosome 21 q. Nature359, 380–387 (1992). ArticleCASPubMed Google Scholar
Petrukhin, K. et al. Physical mapping, cloning, and genetic characterization of the Wilson disease locus. Nature Genet.5, 338–343 (1993). ArticleCASPubMed Google Scholar
Lander, E.S. Finding similarities and differences among genomes. Nature Genet.4, 5–6 (1993). ArticleCASPubMed Google Scholar
Lovett, M., Kere, J. & Hinton, L.M. Direct selection: a method for the isolation of cDNAs encoded by large genomic regions. Proc. natn. Acad. Sci. USA88, 9628–9632 (1991). ArticleCAS Google Scholar
Church, D.M. et al. Isolation of genes from complex sources of mammalian genomic DNA using exon amplification. Nature Genet.6, 98–105 (1994). ArticleCASPubMed Google Scholar
Orita, M., Iwahana, H., Kanazawa, H., Hayashi, K. & Sekiya, T. Detection of polymorhisms of human DNA by gel electrophoresis as single-stranded conformation polymorphisms. Proc. natn. Acad. Sci. U.S.A.86, 2766–2770 (1989). ArticleCAS Google Scholar
Sheffield, V.C. et al. Attachment of a 40 base-pair G+C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes. Proc. natn. Acad. Sci. U.S.A.86, 232–236 (1989). ArticleCAS Google Scholar
Endicott, J. & Spitzer, R.L. A diagnostic interview: the schedule for affective disorders and schizophrenia. Archs. Gen. Psychiat.35, 837–862 (1978). ArticleCAS Google Scholar
Andreasen, N.C. et al. The family history method using diagnostic criteria: reliability and validity. Archs. Gen. Psychiat.34, 129–135 (1977). Article Google Scholar
Spitzer, R.L., Endicott, J. & Robins, E. Research diagnostic criteria: rationale and validity. Archs. Gen. Psychiat.35, 773–779 (1978). ArticleCAS Google Scholar
Straub, R.E. et al. A microsatellite genetic linkage map of human chromosome 18. Genomics15, 48–56 (1993). ArticleCASPubMed Google Scholar
Lathrop, G.M., Lalouel, J.M., Julier, C. & Ott, J. Strategies for multilocus linkage analysis in humans. Proc. natn. Acad. Sci. U.S.A.81, 3443–3446 (1984). ArticleCAS Google Scholar
Ott, J. Analysis of Human Genetic Linkage, Revised Edition. (Johns Hopkins University Press, Baltimore, 1991). Google Scholar
Weeks, D.E., Ott, J. & Lathrop, G.M. SLINK: a general simulation program for linkage analysis. Am. J. hum. Genet.47, A204 (abstr) (1990). Google Scholar
Xie, X. & Ott, J. Determining the effect of a change in affective status on the lod score. Am. J. hum. Genet.47, A205 (abstr) (1990). Google Scholar
Weeks, D.E. & Lange, K. The affected-pedigree-member method of linkage analysis. Am. J. hum. Genet.42, 315–326 (1988). CASPubMedPubMed Central Google Scholar
Sandkuyl, L.A. Analysis of affected sib pairs using information from extended families. Prog. Clin. Biol. Research.329, 117–122 (1989). CAS Google Scholar