Identification of a RING protein that can interact in vivo with the BRCA1 gene product (original) (raw)

References

  1. Hall, J.M. et al. Linkage of early-onset familial breast cancer to chromosome 17q21. Science 250, 1684–1689 (1990).
    Article CAS PubMed Google Scholar
  2. Miki, Y. et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266, 66–71 (1994).
    Article CAS PubMed Google Scholar
  3. Futreal, P.A. et al. BRCA1 mutations in primary breast and ovarian carcinomas. Science 266, 120–122 (1994).
    Article CAS PubMed Google Scholar
  4. Castilla, L.H. et al. Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer. Nature Genet. 8, 387–391 (1994).
    Article CAS PubMed Google Scholar
  5. Simard, J. et al. Common origins of BRCA1 mutations in Canadian breast and ovarian cancer families. Nature Genet. 8, 392–398 (1994).
    Article CAS PubMed Google Scholar
  6. Friedman, L.S. et al. Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families. Nature Genet. 8, 399–404 (1994).
    Article CAS PubMed Google Scholar
  7. Easton, D.F., Bishop, D.T., Ford, D. & Crockford, G.P. Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium. Am. J. Hum. Genet. 52, 678–701 (1993).
    CAS PubMed PubMed Central Google Scholar
  8. Ford, D., Easton, D.F., Bishop, D.T., Narod, S.A. & Goldgar, D.E. Risks of cancer in BRCA1 -mutation carriers. Breast Cancer Linkage Consortium. Lancet 343, 692–695 (1994).
    Article CAS PubMed Google Scholar
  9. Saurin, A.J., Borden, K.L.B., Boddy, M.N. & Freemont, P.S. Does this have a familiar RING? Trends Biochem. Sci. 21, 208–214 (1996).
    Article CAS PubMed Google Scholar
  10. Bennett, M.L. et al. Isolation of the mouse homologue of BRCA1 and genetic mapping to mouse chromosome 11. Genomics 29, 576–581 (1995).
    Article CAS PubMed Google Scholar
  11. Lane, T.F. et al. Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice. Genes Dev. 9, 2712–2722 (1995).
    Article CAS PubMed Google Scholar
  12. Sharan, S.K., Wims, M. & Bradley, A. Murine Brca1: sequence and significance for human missense mutations. Hum. Mot. Genet. 4, 2275–2278 (1995).
    Article CAS Google Scholar
  13. Koonin, E.V., Altschul, S.F. & Bork, P. BRCA1 protein products: functional motifs. Nature Genet. 13, 266–267 (1996).
    Article CAS PubMed Google Scholar
  14. Fields, S. & Song, O. -k. A novel genetic system to detect protein–protein interactions. Nature 340, 245–246 (1989).
    Article CAS PubMed Google Scholar
  15. Chien, C.-t., Bartel, P.L., Sternglanz, R. & Fields, S. The two-hybrid system: A method to identify and clone genes for proteins that interact with a protein of interest. Proc. Natl. Acad. Sci. USA 88, 9578–9582 (1991).
    Article CAS PubMed PubMed Central Google Scholar
  16. Durfee, T. et al. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7, 555–569 (1993).
    Article CAS PubMed Google Scholar
  17. Harper, J.W., Adami, G.R., Wei, N., Keyomarsi, K. & Elledge, S.J. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75, 805–816 (1993).
    Article CAS PubMed Google Scholar
  18. Dang, C.V. et al. Intracellular leucine zipper interactions suggest c-Myc hetero-oligomerization. Mol. Cell. Biol. 11, 954–962 (1991).
    Article CAS PubMed PubMed Central Google Scholar
  19. Hsu, H.-L., Wadman, I. & Baer, R. Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells. Proc. Natl. Acad. Sci. USA 91, 3181–3185 (1994).
    Article CAS PubMed PubMed Central Google Scholar
  20. Tsan, J.T. et al. Mammalian cells as hosts for two-hybrid studies of protein–protein interaction. in The Yeast Two-hybrid System (eds. Bartel, P.L & Fields, S.) (Oxford University Press, Oxford, in the press).
  21. Hopp, T.P. et al. A short polypeptide marker sequence useful for recombinant protein identification and purification. BioTechnology 6, 1204–1210 (1988).
    Article CAS Google Scholar
  22. Bork, P. Hundreds of ankyrin-like repeats in functionally diverse proteins: Mobile modules that cross phyla horizontally. Prot. Struct. Funct. Genet. 17, 363–374 (1993).
    Article CAS Google Scholar
  23. Altschul, S.F., Gish, W., Miller, W., Myers, E.W. & Lipman, D.J. Basic local alignment search tool. J. Mol. Biol. 215, 403–410 (1990).
    Article CAS PubMed Google Scholar
  24. Landschulz, W.H., Johnson, P.F. & McKnight, S.L. The leucine zipper: A hypothetical structure common to a new class of DNA binding proteins. Science 240, 1759–1764 (1988).
    Article CAS PubMed Google Scholar
  25. Murre, C., McCaw, P.S. & Baltimore, D. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell 56, 777–783 (1989).
    Article CAS PubMed Google Scholar
  26. Sadowski, I., Bell, B., Broad, P. & Hollis, M. GAL4 fusion vectors for expression in yeast or mammalian cells. Gene 118, 137–141 (1992).
    Article CAS PubMed Google Scholar
  27. Andersson, S., Davis, D.N., Dahlback, H., Jornvall, H. & Russell, D.W., Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J. Biol. Chem. 264, 8222–8229 (1989).
    CAS PubMed Google Scholar
  28. Smith, D.B. & Johnson, K.S. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67, 31–40 (1988).
    Article CAS PubMed Google Scholar
  29. Guan, K. & Dixon, J.E. Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Analyt. Biochem. 192, 262–267 (1991).
    Article CAS PubMed Google Scholar
  30. Sambrook, J., Fritsch, E.F. & Maniatis, T. Molecular cloning: a laboratory manual (Cold Spring Harbor Press, Cold Spring Harbor, New York, 1989).
    Google Scholar

Download references