ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles (original) (raw)

References

  1. Shiloh, Y. Nat. Rev. Cancer 3, 155–168 (2003).
    Article CAS Google Scholar
  2. Swift, M. et al. N. Engl. J. Med. 316, 1289–1294 (1987).
    Article CAS Google Scholar
  3. Thompson, D. et al. J. Natl. Cancer Inst. 97, 813–822 (2005).
    Article CAS Google Scholar
  4. Fitzgerald, M.G. et al. Nat. Genet. 15, 307–310 (1997).
    Article CAS Google Scholar
  5. Teraoka, S.N. et al. Cancer 92, 479–487 (2001).
    Article CAS Google Scholar
  6. Sommer, S.S. et al. Cancer Genet. Cytogenet. 145, 115–120 (2003).
    Article CAS Google Scholar
  7. Gatti, R.A. et al. Mol. Genet. Metab. 68, 419–423 (1999).
    Article CAS Google Scholar
  8. Chenevix-Trench, G. et al. J. Natl. Cancer Inst. 94, 205–215 (2002).
    Article Google Scholar
  9. Olsen, R.H. et al. Br. J. Cancer 93, 260–265 (2005).
    Article CAS Google Scholar
  10. Meijers-Heijboer, H. et al. Nat. Genet. 31, 55–59 (2002).
    Article CAS Google Scholar
  11. CHEK2 breast cancer case-control consortium. Am. J. Hum. Genet. 74, 1175–1182 (2004).
  12. Antoniou, A.C. et al. Genet. Epidemiol. 25, 190–202 (2003).
    Article Google Scholar
  13. Becker-Catania, S.G. et al. Mol. Genet. Metab. 70, 122–133 (2000).
    Article CAS Google Scholar

Download references

Acknowledgements

We thank the participating families who were recruited to the study by the Familial Breast Cancer Collaboration (UK), which includes the following contributors: A. Ardern-Jones, J. Berg, A. Brady, N. Bradshaw, C. Brewer, G. Brice, B. Bullman, J. Campbell, B. Castle, R. Cetnarsryj, C. Chapman, C. Chu, N. Coates, T. Cole, R. Davidson, A. Donaldson, H. Dorkins, F. Douglas, D. Eccles, R. Eeles, F. Elmslie, D.G. Evans, S. Goff, S. Goodman, D. Goudie, J. Gray, L. Greenhalgh, H. Gregory, N. Haites, S.V. Hodgson, T. Homfray, R.S. Houlston, L. Izatt, L. Jeffers, V. Johnson-Roffey, F. Kavalier, C. Kirk, F. Lalloo, I. Locke, M. Longmuir, J. Mackay, A. Magee, S. Mansour, Z. Miedzybrodzka, J. Miller, P. Morrison, V. Murday, J. Paterson, M. Porteous, N. Rahman, M. Rogers, S. Rowe, S. Shanley, A. Saggar, G. Scott, L. Side, L. Snadden, M. Steel, M. Thomas, S. Thomas. We thank A. Hall and E. Mackie for coordination of sample collection. We acknowledge use of DNA from the British 1958 Birth Cohort collection, funded by the Medical Research Council grant G0000934 and the Wellcome Trust grant 068545/Z/02. M. Ahmed and B. North are supported by the US Army Medical Research and Material Command grant #W81XWH-05-1-0204. This research was supported by the Institute of Cancer Research and by grants from the Breast Cancer Campaign and Cancer Research UK.

Author information

Authors and Affiliations

  1. Section of Cancer Genetics, Institute of Cancer Research, 15 Cotswold Road, Sutton, SM2 5NG, Surrey, UK
    Anthony Renwick, Sheila Seal, Patrick Kelly, Tasnim Chagtai, Munaza Ahmed, Bernard North, Hiran Jayatilake, Rita Barfoot, Katarina Spanova, Michael R Stratton & Nazneen Rahman
  2. Cancer Research UK, Genetic Epidemiology Unit, Strangeways Research Laboratories, University of Cambridge, CB1 8RN, UK
    Deborah Thompson, Lesley McGuffog & Douglas F Easton
  3. Department of Medical Genetics, St Mary's Hospital, Manchester, M13 0JH, UK
    D Gareth Evans
  4. Wessex Clinical Genetics Service, Princess Anne Hospital, Southampton, SO16 6YA, UK
    Diana Eccles
  5. Cancer Genome Project, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, Cambridge, UK
    Michael R Stratton

Authors

  1. Anthony Renwick
    You can also search for this author inPubMed Google Scholar
  2. Deborah Thompson
    You can also search for this author inPubMed Google Scholar
  3. Sheila Seal
    You can also search for this author inPubMed Google Scholar
  4. Patrick Kelly
    You can also search for this author inPubMed Google Scholar
  5. Tasnim Chagtai
    You can also search for this author inPubMed Google Scholar
  6. Munaza Ahmed
    You can also search for this author inPubMed Google Scholar
  7. Bernard North
    You can also search for this author inPubMed Google Scholar
  8. Hiran Jayatilake
    You can also search for this author inPubMed Google Scholar
  9. Rita Barfoot
    You can also search for this author inPubMed Google Scholar
  10. Katarina Spanova
    You can also search for this author inPubMed Google Scholar
  11. Lesley McGuffog
    You can also search for this author inPubMed Google Scholar
  12. D Gareth Evans
    You can also search for this author inPubMed Google Scholar
  13. Diana Eccles
    You can also search for this author inPubMed Google Scholar
  14. Douglas F Easton
    You can also search for this author inPubMed Google Scholar
  15. Michael R Stratton
    You can also search for this author inPubMed Google Scholar
  16. Nazneen Rahman
    You can also search for this author inPubMed Google Scholar

Consortia

The Breast Cancer Susceptibility Collaboration (UK)

Corresponding author

Correspondence toNazneen Rahman.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Supplementary information

Rights and permissions

About this article

Cite this article

Renwick, A., Thompson, D., Seal, S. et al. ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles.Nat Genet 38, 873–875 (2006). https://doi.org/10.1038/ng1837

Download citation