Genome-wide association study of prostate cancer identifies a second risk locus at 8q24 (original) (raw)

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Acknowledgements

The HPFS study is supported by NIH grants CA CA55075 and 5U01CA098233-04. The ACS study is supported by U01 CA098710. The ATBC study is supported by NIH contracts N01-CN-45165, N01-RC-45035 and N01-RC-37004. F.R.S. is supported by an NRSA training grant (T32 CA 09001). P.F. is supported by a UK Engineering and Physical Sciences Research Council Grant (GR/S18786). M.M. is supported by the Wellcome Trust. N.O., R.B.H., S.W., K.Y., N.C., M.T., J.F.F., R.H., S.J.C. and G.T. are supported by the Intramural Research Program of the National Cancer Institute (US National Institutes of Health, Department of Health and Human Services).

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Authors and Affiliations

  1. SAIC-Frederick, National Cancer Institute (NCI)-Frederick Cancer Research and Development Center, Frederick, 21702, Maryland, USA
    Meredith Yeager, Zhaoming Wang, Robert Welch & Brian J Staats
  2. Division of Cancer Epidemiology and Genetics, Department of Health and Human Services (DHHS), Center for Cancer Research, NCI, US National Institutes of Health (NIH), Bethesda, 20892, Maryland, USA
    Meredith Yeager, Richard B Hayes, Sholom Wacholder, Kai Yu, Nilanjan Chatterjee, Zhaoming Wang, Robert Welch, Brian J Staats, Demetrius Albanes, Stephanie Weinstein, Margaret Tucker, Joseph F Fraumeni Jr, Robert Hoover, David J Hunter, Stephen J Chanock & Gilles Thomas
  3. Department of Health and Human Services (DHHS), Pediatric Oncology Branch, Center for Cancer Research, NCI, US National Institutes of Health (NIH), Bethesda, 20892, Maryland, USA
    Nick Orr & Stephen J Chanock
  4. Bioinformed Consulting Services, Gaithersburg, 20877, Maryland, USA
    Kevin B Jacobs
  5. Department of Epidemiology, Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, 02115, Massachusetts, USA
    Peter Kraft, Fredrick R Schumacher & David J Hunter
  6. Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, CB10 1SA, UK
    Mark J Minichiello
  7. Department of Mathematics and Statistics, Lancaster University, Lancaster, LA1 4YF, UK
    Paul Fearnhead
  8. Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, 30329, Georgia, USA
    Eugenia E Calle, Heather Spencer Feigelson, Michael J Thun & Carmen Rodriguez
  9. Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, FIN-00300, Finland
    Jarmo Virtamo
  10. Department of Nutrition, Harvard School of Public Health, Boston, 02115, Massachusetts, USA
    Edward Giovannucci & Walter C Willett
  11. Centre de Recherche pour les Pathologies Prostatiques (CeRePP), Hôpital Tenon, Assistance Publique-Hôpitaux de Paris, Paris, 75970, France
    Geraldine Cancel-Tassin, Olivier Cussenot & Antoine Valeri
  12. Division of Urologic Surgery, Washington University School of Medicine, St. Louis, 63108, Missouri, USA
    Gerald L Andriole
  13. Division of Hematology and Oncology, Columbia University, New York, 10032, New York, USA
    Edward P Gelmann
  14. Office of Cancer Genomics, NCI, NIH, DHHS, Bethesda, 20892, Maryland, USA
    Daniela S Gerhard

Authors

  1. Meredith Yeager
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  2. Nick Orr
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  3. Richard B Hayes
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  4. Kevin B Jacobs
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  5. Peter Kraft
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  6. Sholom Wacholder
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  7. Mark J Minichiello
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  8. Paul Fearnhead
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  9. Kai Yu
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  10. Nilanjan Chatterjee
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  11. Zhaoming Wang
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  12. Robert Welch
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  13. Brian J Staats
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  14. Eugenia E Calle
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  15. Heather Spencer Feigelson
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  16. Michael J Thun
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  17. Carmen Rodriguez
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  18. Demetrius Albanes
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  19. Jarmo Virtamo
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  20. Stephanie Weinstein
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  21. Fredrick R Schumacher
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  22. Edward Giovannucci
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  23. Walter C Willett
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  24. Geraldine Cancel-Tassin
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  25. Olivier Cussenot
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  26. Antoine Valeri
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  27. Gerald L Andriole
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  28. Edward P Gelmann
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  29. Margaret Tucker
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  30. Daniela S Gerhard
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  31. Joseph F Fraumeni Jr
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  32. Robert Hoover
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  33. David J Hunter
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  34. Stephen J Chanock
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  35. Gilles Thomas
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Corresponding author

Correspondence toStephen J Chanock.

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The authors declare no competing financial interests.

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Yeager, M., Orr, N., Hayes, R. et al. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.Nat Genet 39, 645–649 (2007). https://doi.org/10.1038/ng2022

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