Genetic analysis of the mouse brain proteome (original) (raw)

• Klose, J. Protein mapping by combined isoelectric focusing and electrophoresis of mouse tissues. A novel approach to testing for induced point mutations in mammals. Humangenetik 26, 231–243 (1975).
  CAS PubMed Google Scholar
• O'Farrell, P.H. High resolution two-dimensional electrophoresis of proteins. J. Biol. Chem. 250, 4007–4021 (1975).
  CAS PubMed PubMed Central Google Scholar
• Klose, J. & Kobalz, U. Two-dimensional electrophoresis of proteins: an updated protocol and implications for a functional analysis of the genome. Electrophoresis 16, 1034–1059 (1995).
  Article CAS Google Scholar
• Klose, J. Large-gel 2-D electrophoresis. Methods Mol. Biol. 112, 147–172 (1999).
  CAS PubMed Google Scholar
• Anderson, N.G., Metheson, A. & Anderson, N.L. Back to the future: the human protein index (HPI) and the agenda for post-proteomic biology. Proteomics 1, 3–12 (2001).
  Article CAS Google Scholar
• Ferris, S.D., Sage, R.D., Prager, E.M., Ritte, U. & Wilson, A.C. Mitochondrial DNA evolution in mice. Genetics 107, 681–721 (1983).
  Google Scholar
• Avner, P., Amar, L., Dandolo, L. & Guenet, J. L. Genetic analysis of the mouse using interspecific crosses. Trends. Genet. 4, 18–23 (1988).
  Article CAS Google Scholar
• Breen, M. et al. Towards high resolution maps of the mouse and human genomes—a facility for ordering markers to 0.1 cM resolution. Hum. Mol. Genet. 3, 621–627 (1994).
  Article CAS Google Scholar
• Rhodes, M. et al. A high-resolution microsatellite map of the mouse genome. Genome Res. 8, 531–542 (1998).
  Article CAS Google Scholar
• Klose, J. Fractionated extraction of total tissue proteins from mouse and human for 2-D electrophoresis. Methods Mol. Biol. 112, 67–85 (1999).
  CAS PubMed Google Scholar
• Gauss, C., Kalkum, M., Löwe, M., Lehrach, H. & Klose, J. Analysis of the mouse proteome. (I) Brain proteins: separation by two-dimensional electrophoresis and identification by mass spectrometry and genetic variation. Electrophoresis 20, 575–600 (1999).
  Article CAS Google Scholar
• Klose, J. Genotypes and phenotypes. Electrophoresis 20, 643–652 (1999).
  Article CAS Google Scholar
• Damerval, C., Maurice, A., Josse, J. M. & de Vienne, D. Quantitative trait loci underlying gene product variation: a novel perspective for analyzing regulation of genome expression. Genetics 137, 289–301 (1994).
  CAS PubMed PubMed Central Google Scholar
• Lehmann, W.D. in Massenspektrometrie in der Biochemie 410 (Spektrum, Heidelberg, 1996).
  Google Scholar
• Strupat, K., Laras, M., Hillenkamp, F., Eckerskorn, C. & Lottspeich, F. Matrix-assisted laser-desorption ionization mass spectrometry of proteins electroblotted after polyacrylamide gel electrophoresis. Anal. Chem. 66, 464–470 (1994).
  Article CAS Google Scholar
• Thiellement, H. et al. Proteomics for genetic and physiological studies in plants. Electrophoresis 20, 2013–2026 (1999).
  Article CAS Google Scholar
• Janke, C., Holzer, M., Klose, J. & Arendt, T. Distribution of isoforms of the microtubule-associated protein tau in grey and white matter areas of human brain: a two-dimensional gelelectrophoretic analysis. FEBS Lett. 379, 222–226 (1996).
  Article CAS Google Scholar
• Whitney, J.B., Cobb, R.R., Popp, R.A. & O'Rourke, T.W. Detection of neutral amino acid substitutions in proteins. Proc. Natl Acad. Sci. USA 82, 7646–7650 (1985).
  Article CAS Google Scholar
• Scriver, C.R. & Waters, P.J. Monogenic traits are not simple: lessons from phenylketonuria. Trends. Genet. 15, 267–272 (1999).
  Article CAS Google Scholar
• Cargill, M. et al. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nature Genet. 22, 231–238 (1999).
  Article CAS Google Scholar
• Halushka, M.K. et al. Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nature Genet. 22, 239–247 (1999).
  Article CAS Google Scholar
• Sunyaev, S., Ramensky, V. & Bork, P. Towards a structural basis of human non-synonymous single nucleotide polymorphisms. Trends Genet. 16, 198–200 (2000).
  Article CAS Google Scholar
• Lindblad-Toh, K. et al. Large-scale discovery and genotyping of single- divergence of B2m alleles of wild Mus musculus and Mus spretus implies positive selection. Immunogenetics 38, 106–116 (1993).
  Google Scholar
• Lacombe, C. et al. in Protides of the Biological Fluids; Proceedings of the Colloqium Vol. 32 (ed. Peeters, H.) 1001–1003 (Pergamon, Oxford, 1985).
  Google Scholar
• Noel, D., Nikaido, K. & Ames, G.F. A single amino acid substitution in a histidine-transport protein drastically alters its mobility in sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biochemistry 18, 4159–4165 (1979).
  Article CAS Google Scholar
• Litersky, J.M., Scott, C.W. & Johnson, G.V. Phosphorylation, calpain proteolysis and tubulin binding of recombinant human tau isoforms. Brain Res. 604, 32–40 (1993).
  Article CAS Google Scholar
• Gerstner, A., Csapo, Z., Sasvari-Szekely, M. & Guttman, A. Ultrathin-layer sodium dodecyl sulfate gel electrophoresis of proteins: effects of gel composition and temperature on the separation of sodium dodecyl sulfate-protein complexes. Electrophoresis 21, 834–840 (2000).
  Article CAS Google Scholar
• Wiltfang, J. et al. Improved electrophoretic separation and immunoblotting of β-amyloid (A-β) peptides 1–40, 1–42, and 1–43. Electrophoresis 18, 527–532 (1997).
  Article CAS Google Scholar
• Lai, K., Langley, S.D., Dembure, P.P., Hjelm, L.N. & Elsas, L.J. Duarte allele impairs biostability of galactose-1-phosphate uridyltransferase in human lymphoblasts. Hum. Mutat. 11, 28–38 (1998).
  Article CAS Google Scholar
• Burge, C. & Karlin, S. Prediction of complete gene structures in human genomic DNA. J. Mol. Biol. 268, 78–94 (1997).
  Article CAS Google Scholar
• Pesole, G. et al. UTRdb and UTRsite: specialized databases of sequences and functional elements of 5′ and 3′ untranslated regions of eukaryotic mRNAs. Nucleic. Acids Res. 28, 193–196 (2000).
  Article CAS Google Scholar
• Phillips, P.C. From complex traits to complex alleles. Trends. Genet. 15, 6–8 (1999).
  Article CAS Google Scholar
• Le Stunff, C., Fallin, D., Schork, N.J. & Bougneres, P. The insulin gene VNTR is associated with fasting insulin levels and development of juvenile obesity. Nature Genet. 26, 444–446 (2000).
  Article CAS Google Scholar
• Weiss, K.M. & Terwilliger, J.D. How many diseases does it take to map a gene with SNPs? Nature Genet. 26, 151–157 (2000).
  Article CAS Google Scholar
• Silva, A.J. & White, R. Inheritance of allelic blueprints for methylation patterns. Cell 54, 145–152 (1988).
  Article CAS Google Scholar
• Gooley, A.A. & Packer, N.H. in Proteome Research: New Frontiers in Functional Genomics (eds Wilkens, M.R., Williams, K.L., Appel, R.D. & Hochstrasser, D.F.) 65–91 (Springer, Berlin, 2001).
  Google Scholar
• Kato, G.J. Human genetic disease of proteolysis. Hum. Mutat. 13, 87–98 (1999).
  Article CAS Google Scholar
• Neuhoff, V., Arold, N., Taube, D. & Ehrhardt, W. Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G-250 and R-250. Electrophoresis 9, 255–262 (1988).
  Article CAS Google Scholar
• Marcus, K., Immler, D., Sternberger, J. & Meyer, H.E. Identification of platelet proteins separated by two-dimensional gel electrophoresis and analyzed by matrix assisted laser desorption/ionization-time of flight-mass spectrometry and detection of tyrosine-phosphorylated proteins. Electrophoresis 21, 2622–2636 (2000).
  Article CAS Google Scholar
• Zhang, W. & Chait, B.T. ProFound: an expert system for protein identification using mass spectrometric peptide mapping information. Anal. Chem. 72, 2482–2489 (2000).
  Article CAS Google Scholar
• Schalkwyk, L.C. et al. Advanced integrated mouse YAC map including BAC framework. Genome Res. 11, 2142–2150 (2001).
  Article CAS Google Scholar
• Dietrich, W.F. et al. A comprehensive genetic map of the mouse genome. Nature 380, 149–152 (1996).
  Article CAS Google Scholar
• Schalkwyk, L.C. et al. Panel of microsattelite markers for whole-genome scans and radiation hybrid mapping and a mouse family tree. Genome Res. 9, 878–888 (1999).
  Article CAS Google Scholar
• Feinberg, A.P. & Vogelstein, B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132, 6–13 (1983).
  Article CAS Google Scholar
• Church, G.M. & Gilbert, W. The genomic sequencing technique. Prog. Clin. Biol. Res. 177, 17–21 (1985).
  CAS PubMed Google Scholar
• Lander, E.S. et al. MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics 1, 174–181 (1987).
  Article CAS Google Scholar
• Dietrich, W. et al. A genetic map of the mouse suitable for typing intraspecific crosses. Genetics 131, 423–447 (1992).
  CAS PubMed PubMed Central Google Scholar