Spotlight on IL-22-producing NK cell receptor–expressing mucosal lymphocytes (original) (raw)

Nature Immunology volume 10, pages 11–12 (2009)Cite this article

New findings show that a subpopulation of mucosal RORγt+ cells expresses natural killer cell receptors and produces interleukin 22. These innate immune cells may be pivotal in maintaining mucosal homeostasis.

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Figure 1: In the gut, different subsets of RORγt+ cells exist.

Katie Vicari

References

  1. Cupedo, T. et al. Nat. Immunol. 10, 66–74 (2009).
    Article CAS Google Scholar
  2. Luci, C. et al. Nat. Immunol. 10, 75–82 (2009).
    Article CAS Google Scholar
  3. Sanos, S.L. et al. Nat. Immunol. 10, 83–91 (2009).
    Article CAS Google Scholar
  4. Cella, M. et al. Nature advance online publication, doi:10.1038/nature07537 (2 November 2008).
  5. Satoh-Takayama, N. et al. Immunity advance online publication, doi:10.1016/j.immuni.2008.11.001 (11 December 2008).
  6. Mebius, R.E. Nat. Rev. Immunol. 3, 292–303 (2003).
    Article CAS Google Scholar
  7. Zheng, Y. et al. Nat. Med. 14, 282–289 (2008).
    Article CAS Google Scholar
  8. Niess, J.H. et al. Science 307, 254–258 (2005).
    Article CAS Google Scholar
  9. Walzer, T., Jaeger, S., Chaix, J. & Vivier, E. Curr. Opin. Immunol. 19, 365–372 (2007).
    Article CAS Google Scholar
  10. Di Santo, J. Annu. Rev. Immunol. 24, 257–286 (2006).
    Article CAS Google Scholar
  11. Boos, M.D., Yokota, Y., Eberl, G. & Kee, B.L. J. Exp. Med. 204, 1119–1130 (2007).
    Article CAS Google Scholar
  12. Mebius, R.E., Rennert, P. & Weissman, I.L. Immunity 7, 493–504 (1997).
    Article CAS Google Scholar

Download references

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Authors and Affiliations

  1. Department of Medicine, Karl-Johan Malmberg and Hans-Gustaf Ljunggren are with the Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, S-14186 Stockholm, Sweden. hans-gustaf.ljunggren@ki.se,
    Karl-Johan Malmberg & Hans-Gustaf Ljunggren

Authors

  1. Karl-Johan Malmberg
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  2. Hans-Gustaf Ljunggren
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Malmberg, KJ., Ljunggren, HG. Spotlight on IL-22-producing NK cell receptor–expressing mucosal lymphocytes.Nat Immunol 10, 11–12 (2009). https://doi.org/10.1038/ni0109-11

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