Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells (original) (raw)

References

  1. Banchereau, J. & Steinman, R.M. Dendritic cells and the control of immunity. Nature 392, 245–252 (1998).
    Article CAS Google Scholar
  2. Santambrogio, L., Sato, A.K., Fischer, F.R., Dorf, M.E. & Stern, L.J. Abundant empty class II MHC molecules on the surface of immature dendritic cells. Proc. Natl. Acad. Sci. USA 96, 15050–15055 (1999).
    Article CAS Google Scholar
  3. Santambrogio, L. et al. Extracellular antigen processing and presentation by immature dendritic cells. Proc. Natl. Acad. Sci. USA 96, 15056–15061 (1999).
    Article CAS Google Scholar
  4. Trombetta, E.S., Ebersold, M., Garrett, W., Pypaert, M. & Mellman, I. Activation of lysosomal function during dendritic cell maturation. Science 299, 1400–1403 (2003).
    Article CAS Google Scholar
  5. Kleijmeer, M. et al. Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells. J. Cell Biol. 155, 53–63 (2001).
    Article CAS Google Scholar
  6. Barois, N., de Saint-Vis, B., Lebecque, S., Geuze, H.J. & Kleijmeer, M.J. MHC class II compartments in human dendritic cells undergo profound structural changes upon activation. Traffic 3, 894–905 (2002).
    Article CAS Google Scholar
  7. Chow, A., Toomre, D., Garrett, W. & Mellman, I. Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature 418, 988–994 (2002).
    Article CAS Google Scholar
  8. Boes, M. et al. T-cell engagement of dendritic cells rapidly rearranges MHC class II transport. Nature 418, 983–988 (2002).
    Article CAS Google Scholar
  9. Villadangos, J.A. et al. MHC class II expression is regulated in dendritic cells independently of invariant chain degradation. Immunity 14, 739–749 (2001).
    Article CAS Google Scholar
  10. Inaba, K. et al. The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli. J. Exp. Med. 191, 927–936 (2000).
    Article CAS Google Scholar
  11. Barton, G.M. & Rudensky, A.Y. An altered invariant chain protein with an antigenic peptide in place of CLIP forms SDS-stable complexes with class II alphabeta dimers and facilitates highly efficient peptide loading. Int. Immunol. 10, 1159–1165 (1998).
    Article CAS Google Scholar
  12. Traub, L.M., Kornfeld, S. & Ungewickell, E. Different domains of the AP-1 adaptor complex are required for Golgi membrane binding and clathrin recruitment. J. Biol. Chem. 270, 4933–4942 (1995).
    Article CAS Google Scholar
  13. Traub, L.M., Downs, M.A., Westrich, J.L. & Fremont, D.H. Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly. Proc. Natl. Acad. Sci. USA 96, 8907–8912 (1999).
    Article CAS Google Scholar
  14. Bonifacino, J.S. & Traub, L.M. Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu. Rev. Biochem. 72, 395–447 (2003).
    Article CAS Google Scholar
  15. Doray, B., Ghosh, P., Griffith, J., Geuze, H.J. & Kornfeld, S. Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi network. Science 297, 1700–1703 (2002).
    Article CAS Google Scholar
  16. Hofmann, M.W. et al. The leucine-based sorting motifs in the cytoplasmic domain of the invariant chain are recognized by the clathrin adaptors AP1 and AP2 and their medium chains. J. Biol. Chem. 274, 36153–36158 (1999).
    Article CAS Google Scholar
  17. Kongsvik, T.L., Honing, S., Bakke, O. & Rodionov, D.G. Mechanism of interaction between leucine-based sorting signals from the invariant chain and clathrin-associated adaptor protein complexes AP1 and AP2. J. Biol. Chem. 277, 16484–16488 (2002).
    Article CAS Google Scholar
  18. Brachet, V., Pehau-Arnaudet, G., Desaymard, C., Raposo, G. & Amigorena, S. Early endosomes are required for major histocompatiblity complex class II transport to peptide-loading compartments. Mol. Biol. Cell 10, 2891–2904 (1999).
    Article CAS Google Scholar
  19. Glickman, J.N., Morton, P.A., Slot, J.W., Kornfeld, S. & Geuze, H. The biogenesis of the MHC class II compartment in human I-cell disease B lymphoblasts. J. Cell Biol. 132, 769–785 (1996).
    Article CAS Google Scholar
  20. Wong, S.H., Santambrogio, L. & Strominger, J.L. Caspases and nitric oxide broadly regulate dendritic cell maturation and surface expression of class II MHC proteins. Proc. Natl. Acad. Sci. USA 101, 17783–17788 (2004).
    Article CAS Google Scholar
  21. Dranoff, G. et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl. Acad. Sci. USA 90, 3539–3543 (1993).
    Article CAS Google Scholar
  22. Winzler, C. et al. Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures. J. Exp. Med. 185, 317–328 (1997).
    Article CAS Google Scholar
  23. Rossig, L. et al. Nitric oxide inhibits caspase-3 by S-nitrosylation in vivo. J. Biol. Chem. 274, 6823–6826 (1999).
    Article CAS Google Scholar
  24. Bogdan, C. Nitric oxide and the immune response. Nat. Immunol. 2, 907–916 (2001).
    Article CAS Google Scholar
  25. Li, J., Billiar, T.R., Talanian, R.V. & Kim, Y.M. Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation. Biochem. Biophys. Res. Commun. 240, 419–424 (1997).
    Article CAS Google Scholar
  26. Woo, M. et al. Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity. Nat. Immunol. 4, 1016–1022 (2003).
    Article CAS Google Scholar
  27. Nogi, T. et al. Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain. Nat. Struct. Biol. 9, 527–531 (2002).
    CAS Google Scholar
  28. Duncan, M.C., Costaguta, G. & Payne, G.S. Yeast epsin-related proteins required for Golgi-endosome traffic define a γ-adaptin ear-binding motif. Nat. Cell Biol. 5, 77–81 (2003).
    Article CAS Google Scholar
  29. Mills, I.G. et al. EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking. J. Cell Biol. 160, 213–222 (2003).
    Article Google Scholar
  30. Bremnes, T., Lauvrak, V., Lindqvist, B. & Bakke, O. A region from the medium chain adaptor subunit (mu) recognizes leucine- and tyrosine-based sorting signals. J. Biol. Chem. 273, 8638–8645 (1998).
    Article CAS Google Scholar
  31. Kang, S., Liang, L., Parker, C.D. & Collawn, J.F. Structural requirements for major histocompatibility complex class II invariant chain endocytosis and lysosomal targeting. J. Biol. Chem. 273, 20644–20652 (1998).
    Article CAS Google Scholar
  32. Nordeng, T.W. et al. The cytoplasmic tail of invariant chain regulates endosome fusion and morphology. Mol. Biol. Cell 13, 1846–1856 (2002).
    Article CAS Google Scholar
  33. Robinson, M.S. & Bonifacino, J.S. Adaptor-related proteins. Curr. Opin. Cell Biol. 13, 444–453 (2001).
    Article CAS Google Scholar
  34. Hirst, J., Motley, A., Harasaki, K., Peak Chew, S.Y. & Robinson, M.S. EpsinR: an ENTH domain-containing protein that interacts with AP-1. Mol. Biol. Cell 14, 625–641 (2003).
    Article CAS Google Scholar
  35. Mayhew, T.M., Griffiths, G. & Lucocq, J.M. Applications of an efficient method for comparing immunogold labelling patterns in the same sets of compartments in different groups of cells. Histochem. Cell Biol. 122, 171–177 (2004).
    Article CAS Google Scholar
  36. Wilhelm, S., Wagner, H. & Hacker, G. Activation of caspase-3-like enzymes in non-apoptotic T cells. Eur. J. Immunol. 28, 891–900 (1998).
    Article CAS Google Scholar
  37. Alam, A., Cohen, L.Y., Aouad, S. & Sekaly, R.P. Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells. J. Exp. Med. 190, 1879–1890 (1999).
    Article CAS Google Scholar
  38. Mukerjee, N., McGinnis, K.M., Gnegy, M.E. & Wang, K.K. Caspase-mediated calcineurin activation contributes to IL-2 release during T cell activation. Biochem. Biophys. Res. Commun. 285, 1192–1199 (2001).
    Article CAS Google Scholar
  39. Zermati, Y. et al. Caspase activation is required for terminal erythroid differentiation. J. Exp. Med. 193, 247–254 (2001).
    Article CAS Google Scholar
  40. Kolbus, A. et al. Raf-1 antagonizes erythroid differentiation by restraining caspase activation. J. Exp. Med. 196, 1347–1353 (2002).
    Article CAS Google Scholar
  41. Moretti, A. et al. Essential myosin light chain as a target for caspase-3 in failing myocardium. Proc. Natl. Acad. Sci. USA 99, 11860–11865 (2002).
    Article CAS Google Scholar
  42. Newton, K. & Strasser, A. Caspases signal not only apoptosis but also antigen-induced activation in cells of the immune system. Genes Dev. 17, 819–825 (2003).
    Article CAS Google Scholar
  43. Page, L.J., Sowerby, P.J., Lui, W.W. & Robinson, M.S. γ-synergin: an EH domain-containing protein that interacts with γ-adaptin. J. Cell Biol. 146, 993–1004 (1999).
    Article CAS Google Scholar
  44. Hirst, J. et al. A family of proteins with γ-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome. J. Cell Biol. 149, 67–80 (2000).
    Article CAS Google Scholar
  45. Salamero, J., Le Borgne, R., Saudrais, C., Goud, B. & Hoflack, B. Expression of major histocompatibility complex class II molecules in HeLa cells promotes the recruitment of AP-1 Golgi-specific assembly proteins on Golgi membranes. J. Biol. Chem. 271, 30318–30321 (1996).
    Article CAS Google Scholar
  46. Mallard, F. et al. Direct pathway from early/recycling endosomes to the Golgi apparatus revealed through the study of shiga toxin B-fragment transport. J. Cell Biol. 143, 973–990 (1998).
    Article CAS Google Scholar
  47. Meyer, C. μ1A-adaptin-deficient mice: lethality, loss of AP-1 binding and rerouting of mannose 6-phosphate receptors. EMBO J. 19, 2193–2203 (2000).
    Article CAS Google Scholar
  48. Waguri, S. et al. Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cells. Mol. Biol. Cell 14, 142–155 (2003).
    Article CAS Google Scholar
  49. Corradin, S.B., Mauel, J., Donini, S.D., Quattrocchi, E. & Ricciardi-Castagnoli, P. Inducible nitric oxide synthase activity of cloned murine microglial cells. Glia 7, 255–262 (1993).
    Article CAS Google Scholar
  50. Raposo, G. & Kleijmeer, M.J. in Handbook of Experimental Immunology 5th edn. Ch. 208 (ed. Herzenberg, L.W., Herzenberg, L.A. and Blackwell, C.) 1–11 (I. Blackwell Science, Cambridge, Massachusetts, 1997).
    Google Scholar
  51. Villadangos, J.A. et al. Proteases involved in MHC class II antigen presentation. Immunol. Rev. 172, 109–120 (1999).
    Article CAS Google Scholar

Download references