Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D (original) (raw)

• Olcese, L. et al. Human killer cell activatory receptors for MHC class I molecules are included in a multimeric complex expressed by natural killer cells. J. Immunol. 158, 5083–5086 (1997).
  CAS Google Scholar
• Lanier, L.L., Corliss, B.C., Wu, J., Leong, C. & Phillips, J.H. Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells. Nature 391, 703–707 (1998).
  Article CAS Google Scholar
• Tomasello, E. et al. Combined natural killer cell and dendritic cell functional deficiency in KARAP/DAP12 loss-of–function mutant mice. Immunity 13, 355–364 (2000).
  Article CAS Google Scholar
• Bakker, A.B.H. et al. DAP12-deficient mice fail to develop autoimmunity due to impaired antigen priming. Immunity 13, 345–353 (2000).
  Article CAS Google Scholar
• Wu, J. et al. An activating immunoreceptor complex formed by NKG2D and DAP10. Science 285, 730–732 (1999).
  Article CAS Google Scholar
• Chang, C. et al. KAP10, a novel transmembrane adapter protein genetically linked to DAP12 but with unique signaling properties. J. Immunol. 163, 4652–4654 (1999).
  Google Scholar
• Wu, J., Cherwinski, H., Spies, T., Phillips, J.H. & Lanier, L.L. DAP10 and DAP12 form distinct, but functionally cooperative, receptor complexes in natural killer cells. J. Exp. Med. 192, 1059–1067 (2000).
  Article CAS Google Scholar
• Diefenbach, A., Jamieson, A.M., Liu, S.D., Shastri, N. & Raulet, D.H. Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nature Immunol. 1, 119–126 (2000).
  Article CAS Google Scholar
• Jamieson, A.M. et al. The role of the NKG2D immunoreceptor in immune cell activation and natural killing. Immunity 17, 19–29 (2002).
  Article CAS Google Scholar
• Cerwenka, A. et al. Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity 12, 721–727 (2000).
  Article CAS Google Scholar
• Bauer, S. et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285, 727–729 (1999).
  Article CAS Google Scholar
• Cosman, D. et al. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity 14, 123–133 (2001).
  Article CAS Google Scholar
• Groh, V. et al. Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium. Proc. Natl. Acad. Sci. USA 93, 12445–12450 (1996).
  Article CAS Google Scholar
• Diefenbach, A. & Raulet, D.H. Strategies for target cell recognition by natural killer cells. Immunol. Rev. 181, 170–184 (2001).
  Article CAS Google Scholar
• Diefenbach, A., Jensen, E.R., Jamieson, A.M. & Raulet, D.H. Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity. Nature 413, 165–171 (2001).
  Article CAS Google Scholar
• Pende, D. et al. Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin. Eur. J. Immunol. 31, 1076–1086 (2001).
  Article CAS Google Scholar
• Groh, V. et al. Costimulation of CD8αβ T cells by NKG2D via engagement by MIC induced on virus-infected cells. Nature Immunol. 2, 255–260 (2001).
  Article CAS Google Scholar
• Vance, R.E., Tanamachi, D.M., Hanke, T. & Raulet, D.H. Cloning of a mouse homolog of CD94 extends the family of C-type lectins on murine natural killer cells. Eur. J. Immunol. 27, 3236–3241 (1997).
  Article CAS Google Scholar
• Ho, E.L. et al. Murine Nkg2d and Cd94 are clustered within the natural killer complex and are expressed independently in natural killer cells. Proc. Natl. Acad. Sci. USA 95, 6320–6325 (1998).
  Article CAS Google Scholar
• Lucas, M. et al. Massive inflammatory syndrome and lymphocytic immunodeficiency in KARAP/DAP12 transgenic mice. Eur. J. Immunol. 32, 2653–2663 (2002).
  Article CAS Google Scholar
• Medzhitov, R. & Janeway, C.A. Jr. Decoding the patterns of self and nonself by the innate immune system. Science 296, 298–300 (2002).
  Article CAS Google Scholar
• Gilfillan, S., Ho, E.L., Cella, M., Yokoyama, W.M. & Colonna1, M. NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation. Nat. Immunol.; published online 11 November 2002 (doi:10.1038/ni857).
• Brooks, C.G., Urdal, D.L. & Henney, C.S. Lymphokine-driven “differentiation” of cytotoxic T-cell clones into cells with NK-like specificity: correlations with display of membrane macromolecules. Immunol. Rev. 72, 43–72 (1983).
  Article CAS Google Scholar
• Mingari, M.C., Moretta, A. & Moretta, L. Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell responses. Immunol. Today 19, 153–157 (1998).
  Article CAS Google Scholar
• Uhrberg, M. et al. The repertoire of killer cell Ig-like receptor and CD94:NKG2A receptors in T cells: clones sharing identical αβ TCR rearrangement express highly diverse killer cell Ig-like receptor patterns. J. Immunol. 166, 3923–3932 (2001).
  Article CAS Google Scholar
• Glas, R. et al. Recruitment and activation of natural killer (NK) cells in vivo determined by the target cell phenotype: An adaptive component of NK cell-mediated responses. J. Exp. Med. 191, 129–138 (2000).
  Article CAS Google Scholar
• Cosson, P., Lankford, S.P., Bonifacino, J.S. & Klausner, R.D. Membrane protein association by potential intramembrane charge pairs. Nature 351, 414–416 (1991).
  Article CAS Google Scholar
• Klausner, R.D., Lippincott-Schwartz, J. & Bonifacino, J.S. The T cell antigen receptor: insights into organelle biology. Annu. Rev. Cell Biol. 6, 403–431 (1990).
  Article CAS Google Scholar
• Houchins, J.P., Yabe, T., McSherry, C. & Bach, F.H. DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells. J. Exp. Med. 173, 1017–1020 (1991).
  Article CAS Google Scholar
• Wilson, M.J., Haude, A. & Trowsdale, J. The mouse Dap10 gene. Immunogenetics 53, 347–350 (2001).
  Article CAS Google Scholar
• Howard, F.D., Rodewald, H.R., Kinet, J.P. & Reinherz, E.L. CD3ζ subunit can substitute for the gamma subunit of Fcε receptor type I in assembly and functional expression of the high- affinity IgE receptor: evidence for interreceptor complementation. Proc. Natl. Acad. Sci. USA 87, 7015–7019 (1990).
  Article CAS Google Scholar
• Orloff, D.G., Ra, C.S., Frank, S.J., Klausner, R.D. & Kinet, J.P. Family of disulphide-linked dimers containing the ζ and ε chains of the T-cell receptor and the γ chain of Fc receptors. Nature 347, 189–191 (1990).
  Article CAS Google Scholar
• Vivier, E. et al. Tyrosine phosphorylation of the FcγRIII(CD16): ζ complex in human natural killer cells. Induction by antibody-dependent cytotoxicity but not by natural killing. J. Immunol. 146, 206–210 (1991).
  CAS PubMed Google Scholar
• Hayes, S.M. & Love, P.E. Distint structure and signaling potential of the γδ TCR complex. Immunity 16, 827–838 (2002).
  Article CAS Google Scholar
• Tatusova, T.A. & Madden, T.L. BLAST 2 sequences, a new tool for comparing protein and nucleotide sequences. FEMS Microbiol. Lett. 174, 247–250 (1999).
  Article CAS Google Scholar
• Portnoy, D.A., Jacks, P.S. & Hinrichs, D.J. Role of hemolysin for the intracellular growth of Listeria monocytogenes. J. Exp. Med. 167, 1459–1471 (1988).
  Article CAS Google Scholar
• Diefenbach, A. et al. Type 1 interferon (IFNα/β) and type 2 nitric oxide synthase regulate the innate immune response to a protozoan parasite. Immunity 8, 77–87 (1998).
  Article CAS Google Scholar
• Hanke, T. et al. Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity 11, 67–77 (1999).
  Article CAS Google Scholar
• Diefenbach, A., Schindler, H., Röllinghoff, M., Yokoyama, W.M. & Bogdan, C. Requirement for type 2 NO synthase for IL-12 signaling in innate immunity. Science 284, 951–955 (1999).
  Article CAS Google Scholar
• Liao, N., Bix, M., Zijlstra, M., Jaenisch, R. & Raulet, D. MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science 253, 199–202 (1991).
  Article CAS Google Scholar
• Koo, G.C. & Peppard, J.R. Establishment of monoclonal anti-NK-1.1 antibody. Hybridoma 3, 301–303 (1984).
  Article CAS Google Scholar
• Coles, M.C., McMahon, C.W., Takizawa, H. & Raulet, D.H. Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. Eur. J. Immunol. 30, 236–244 (2000).
  Article CAS Google Scholar
• Murali-Krishna, K. et al. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity 8, 177–187 (1998).
  Article CAS Google Scholar