Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease (original) (raw)

• Björklund, A. & Stenevi, U. Reconstruction of the nigrostriatal dopamine pathway by intracerebral nigral transplants. Brain Res. 177, 555–560 (1979).
  Article Google Scholar
• Perlow, M.J. et al. Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system. Science 204, 643–647 (1979).
  Article CAS Google Scholar
• Lindvall, O. Prospects of transplantation in human neurodegenerative diseases. Trends Neurosci. 14, 376–384 (1991).
  Article CAS Google Scholar
• Ahlskog, J.E. Cerebral transplantation for Parkinson's disease: current progress and future prospects. Mayo clin. Proc. 68, 578–591 (1993).
  Article CAS Google Scholar
• Lindvall, O. et al. Transplantation of fetal dopamine neurons in Parkinson's disease: one-year clinical and neurophysiological observations in two patients with putaminal implants. Ann. Neurol. 31, 166–173 (1992).
  Article Google Scholar
• Redmond, D.E., et al. Fetal neural graft survival. Lancet 336, 820–822 (1990).
  Article Google Scholar
• Brundin, P. & Björklund, A. Survival, growth and function of dopaminergic neurons grafted to the brain. Prog. Brain Res. 71, 293–308 (1987).
  Article CAS Google Scholar
• Mayer, E., Fawcett, J.W. & Dunnett, S.B. Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons. II. Effects on nigral transplants in vivo. Neurosdence 56, 389–398 (1993).
  Article CAS Google Scholar
• Steinbusch, H.W.M., Vermeulen, R.J. & Tonnaer, J.A.D.M. Basic fibroblast growth factor enhances survival and sprouting of fetal dopaminergic cells implanted in the denervated rat caudate-putamen: preliminary observations. Prog. Brain res. 82, 81–86 (1990).
  Article CAS Google Scholar
• Matsuda, S., Saito, H. & Nishiyama, N. Effect of basic fibroblast growth factor on neurons cultured from various regions of postnatal brain. Japan J. Pharmacol. 59, 365–370 (1992).
  Article CAS Google Scholar
• Kawaja, M.D. & Gage, F.H. Morphological and neurochemical features of cultured primary skin fibroblasts of Fischer 344 rats following striatal implantation. J. comp. Neurol. 317, 102–116 (1992).
  Article CAS Google Scholar
• Ray, J. et al. Expression of biologically active basic fibroblast growth factor by genetically modified rat primary skin fibroblasts. J. Neurochem. 64 (1995).
  Article Google Scholar
• Brundin, P., Isacson, O. & Björklund, A. Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival. Brain Res. 331, 251–259 (1985).
  Article CAS Google Scholar
• Schmidt, R.H., Bjouml;rklund, A., Stenevi, U., Dunnett, S.B. & Gage, F.H. Activity of intrastriatal nigral suspension implants as assessed by measurements of dopamine synthesis and metabolism. Acta physiol. Scand. Suppl. 522, 19–28 (1983).
  CAS PubMed Google Scholar
• Blam, S.B. et al. Addition of growth hormone secretion signal to basic fibroblast growth factor results in cell transformation and secretion of aberrant forms of the protein. Oncogene 3, 129–136 (1988).
  CAS PubMed Google Scholar
• Baird, A. & Bölhen, P. in: Peptide growth factors and their receptors. 1 (eds Sporn, M.B. & Roberts, A.B.) 369–418 (Springer-Verlang, 1991).
  Book Google Scholar
• Gonzalez, A.M. et al. Storage, metabolism, and processing of [125I]-fibroblast growth factor-2 after intracerebral injection. Brain Res. (in the press).
• Baird, A. & Ling, N. Fibroblast growth factors are present in the extracellular matrix produced by endothelial cells in vitro: implications for a role of heparinase-like enzymes in the neovascular response. Biochem. Biophys. res. Comm. 142, 428–437 (1987).
  Article CAS Google Scholar
• Vlodavsky, I. et al. Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix. Proc. natn. Acad. Sci. USA. 84, 2292–2296 (1987).
  Article CAS Google Scholar
• Flaumenhaft, R., Moscatelli, D., Saksela, O. & Rifkin, D.B. Role of extracellular matrix in the action of basic fibroblast growth factor: matrix as a source of growth factor for long-term stimulation of plasminogen activator production and DNA synthesis. J. cell. Physiol. 140, 75–81 (1989).
  Article CAS Google Scholar
• Knusel, B., Michel, P.P., Schwaber, J.S. & Hefti, F. Selective and nonselective stimulation of central cholinergic and dopamine development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II. J. Neurosci. 10, 558–570 (1990).
  Article CAS Google Scholar
• Engele, J. & Bohn, M.C. The neurotrophic effects of basic fibroblast growth factors on dopaminergic neurons in vitro are nediated by mesencephalic glia. J. Neurosci. 11, 3070–3078 (1991).
  Article CAS Google Scholar
• Mayer, E., Dunnett, S.B., Pellitteri, R., & Fawcett, J.W. Basic fibroblast growth factor promotes the survival of embryonic mesencephalic dopaminergic neurons. I. Effects in vitro. Neuroscience 56, 379–388 (1993).
  Article CAS Google Scholar
• Lin, L.-F.H., Doherty, D.H., Lile, J.D., Bektesh, S. & Collins, F. GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260, 1130–1132 (1993).
  Article CAS Google Scholar
• Yoshida, K. & Gage, F.H. Fibroblast growth factors stimulate nerve growth factor synthesis and secretion by astrocytes. Brain Res. 538, 118–126 (1991).
  Article CAS Google Scholar
• Yoshida, K. & Gage, F.H. Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines. Brain Res. 569, 14–25 (1992).
  Article CAS Google Scholar
• Yoshida, K. et al. Cytokine regulation of nerve growth factor-mediated cholinergic neurotrophic activity synthesized by astrocytes and fibroblasts. J. Neurochem. 59, 919–931 (1992).
  Article CAS Google Scholar
• Finger, S. & Dunnett, S.B. Nimodipine enhances growth and vascularization of neural grafts. Exp. Neurol. 104, 1–9 (1989).
  Article CAS Google Scholar
• Shimasaki, S. et al. Complementary DNA cloning and sequencing of rat ovarian basic fibroblast growth factor and tissue distribution study of its mRNA. Biochem. Biophys. res. Comm. 157, 256–263 (1988).
  Article CAS Google Scholar
• Kawaja, M.D. et al. in Neural Transplantation. A Practical Approach, (eds. Dunnett, S.B. & Bjorklund, A) 21–55 (Oxford University Press, New York, 1992).
  Google Scholar
• Abercrombie, M. Estimation of nuclear population from microtome sections. Anat. Rec. 94, 239–247 (1946)
  Article CAS Google Scholar