Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells (original) (raw)
References
Lynch, R.G. et al. Immunoregulation of murine myeloma cell growth and differentiation: A monoclonal model of B cell differentiation. Immunol. Rev.48, 45–80 (1979). ArticleCAS Google Scholar
Levy, R., Hatzubia, A., Brown, S., Maloney, D. & Dilley, J. Immunoglobulin idiotype: A tumor-specific antigen for human B-cell lymphomas. in Malignant Lymphomas, ch. 5 (Academic Press, New York, 1982). Google Scholar
Maloney, D.G., Kaminski, M.S., Burowski, D., Haimovich, J. & Levy, R. Monoclonal anti-idiotype antibodies against the murine B cell lymphoma 38C13: Characterization and use as probes for the biology of the tumor in vivo and in vitro. Hybridoma4, 191–209 (1985). ArticleCAS Google Scholar
Miller, R.A., Maloney, D.G., Warnke, R. & Levy, R. Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody. N. Engl. J. Med.306, 517–522 (1982). ArticleCAS Google Scholar
Maloney, D.G. et al. Monoclonal anti-idiotype antibody therapy of B-cell lymphoma: The addition of a short course of chemotherapy does not interfere with the antitumor effect nor prevent the emergence of idiotype-negative variant cells. Blood80, 1502–1510 (1992). CASPubMed Google Scholar
Campbell, M.J., Esserman, L., Byars, N.E., Allison, A.C. & Levy, R. Idiotype vaccination against murine B cell lymphoma. Humoral and cellular requirements for the full expression of antitumor immunity. J. Immunol.145, 1029–1036 (1990). CASPubMed Google Scholar
Tao, M.H. & Levy, R. Idiotype/granulocyte-macrophage colony-stimulating factor fusion protein as a vaccine for B-cell lymphoma. Nature362, 755758 (1993). Article Google Scholar
Chen, T.T., Tao, M.H. & Levy, R. Idiotype-cytokine fusion proteins as cancer vaccines. Relative efficacy of IL-2, IL-4, and granulocyte-macrophage colony-stimulating factor. J. Immunol.153, 4775–4787 (1994). CASPubMed Google Scholar
George, A.J., Folkard, S.G., Hamblin, T.J. & Stevenson, F.K. Idiotypic vaccination as a treatment for a B cell lymphoma. J. Immunol.141, 2168–2174 (1988). CASPubMed Google Scholar
Campbell, M.J., Esserman, L. & Levy, R. Immunotherapy of established murine B cell lymphoma: Combination of idiotype immunization and cyclophos-phamide. J. Immunol.141, 3227–3233 (1988). CASPubMed Google Scholar
Hsu, F.J. et al. Clinical trials of idiotype-specific vaccine in B-cell lymphomas. Ann. NY Acad. Sci.690, 385–387 (1993). ArticleCAS Google Scholar
Kwak, L.W. et al. Induction of immune responses in patients with B-cell lymphoma against the surface-immunoglobulin idiotype expressed by their tumors. N. Engl. J. Med.327, 1209–1215 (1992). ArticleCAS Google Scholar
McCabe, B.J. et al. Minimal determinant expressed by a recombinant vaccinia virus elicits therapeutic antitumor cytolytic T lymphocyte responses. Cancer Res.55, 1741–1747 (1995). CASPubMedPubMed Central Google Scholar
Kantor, J. et al. Immunogenicity and safety of a recombinant vaccinia virus vaccine expressing the carcinoembryonic antigen gene in a nonhuman primate. Cancer Res.52, 6917–6925 (1992). CASPubMed Google Scholar
Steinman, R.M. The dendritic cell system and its role in irnmunogenicity. Annu Rev. Immunol.9, 271–296 (1991). ArticleCAS Google Scholar
Larsen, C.P. et al. Regulation of immunostimulatory function and costimula-tory molecule (B7-1 and B7-2) expression on murine dendritic cells. J. Immunol.152, 5208–5219 (1994). CASPubMed Google Scholar
Hathcock, K.S., Laszlo, G., Pucillo, C., Linsley, P. & Hodes, R.J. Comparative analysis of B7-1 and B7-2 costimulatory ligands: Expression and function. J. Exp. Med.180, 631–640 (1994). ArticleCAS Google Scholar
Hart, D.N.J. & McKenzie, J.L. Isolation and characterization of human tonsil dendritic cells. J. Exp. Med.168, 157–170 (1988). ArticleCAS Google Scholar
Freudenthal, P.S. & Steinman, R.M. The distinct surface of human blood dendritic cells, as observed after an improved isolation method. Proc. Natl. Acad. Sci. USA87, 7698–7702 (1990). ArticleCAS Google Scholar
Macatonia, S.E. et al. Dendritic cells produce IL-12 and direct the development of Thl cells from naive CD4+ T cells. J. Immunol.154, 5071–5079 (1995). CASPubMed Google Scholar
Pure, E. et al. Antigen processing by epidermal Langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chain. J. Exp. Med.172, 1459–1469 (1990). ArticleCAS Google Scholar
Inaba, K., Metlay, J.P., Crowley, M.T. & Steinman, R.M. Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ. J. Exp. Med.172, 631–640 (1990). ArticleCAS Google Scholar
Mehta, D.A., Markowicz, S. & Engleman, E.G. Generation of antigen-specific CD8+ CTLs from naive precursors. J. Immunol.153, 996–1003 (1994). Google Scholar
Mehta, D.A., Markowicz, S. & Engleman, E.G. Generation of antigen-specific CD4+ T cell lines from naive precursors. Ear. J. Immunol.25, 1206–1211 (1995). Article Google Scholar
Fagnoni, F.F. et al. Role of B70/B7-2 in CD4+ T cell immune responses induced by dendritic cells. Immunology85, 467–474 (1995). CASPubMedPubMed Central Google Scholar
Flamand, V. et al. Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo. Eur. J. Immunol.24, 605–610 (1994). ArticleCAS Google Scholar
Boog, C.J. et al. Abolition of specific immune response defect by immunization with dendritic cells. Nature318, 59–62 (1985). ArticleCAS Google Scholar
Takamizawa, M., Fagnoni, F., Mehta, D.A., Rivas, A. & Engleman, E.G. Cellular and molecular basis of human gamma delta T cell activation: Role of accessory molecules in alloactivation. J. Clin. Invest.95 296–303 (1995). ArticleCAS Google Scholar
Carroll, W.L., Thielemans, K., Dilley, J. & Levy, R. Mouse × human heterohy-bridomas as fusion partners with human B cell tumors. J. Immunol. Methods89, 61–72 (1986). ArticleCAS Google Scholar
Koch, F. et al. Antigen processing in populations of mature murine dendritic cells is caused by subsets of incompletely matured cells. J. Immunol.155, 93–100 (1995). CASPubMed Google Scholar
Nijman, H.W. et al. Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells. J. Exp. Med.182, 163–174 (1995). ArticleCAS Google Scholar
Boel, P. et al. BAGE: A new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes. Immunity2, 167–175 (1995). ArticleCAS Google Scholar
Marchand, M., Brasseur, F., van der Bruggen, P., Coulie, P., & Boon, T., Perspectives for immunization of HLA-A1 patients carrying a malignant melanoma expressing gene MAGE-1. Dermatology186, 278–280 (1993). ArticleCAS Google Scholar
Kotera, Y., Fontenot, J.D., Pecher, G., Metzgar, R.S. & Finn, O.J. Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic, and colon cancer patients. Cancer Res.54, 2856–2860 (1994). CASPubMed Google Scholar
Caux, C., Dezutter, D.C., Schmitt, D. & Banchereau, J. GM-CSF and TNF-alpha cooperate in the generation of dendritic Langerhans cells. Nature360, 258–261 (1992). ArticleCAS Google Scholar
Romani, N. et al. Proliferating dendritic cell progenitors in human blood. J. Exp. Med.180, 83–93 (1994). ArticleCAS Google Scholar
Sallusto, F. & Lanzavecchia, A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med.179 1109–1118 (1994). ArticleCAS Google Scholar
Hsu, F.J. & Levy, R. Preferential use of the VH4 immunoglobulin gene family by diffuse large cell lymphoma. Blood86, 3072–3082 (1995). CASPubMed Google Scholar
Grabstein, K. . in Selected Methods in Cellular Immunology (eds. Mishell, B.B. & Shiigi, S.M.) 124–137 (Freeman, San Francisco, 1980). Google Scholar