Glycosylation changes of IgG associated with rheumatooid arthritis can activate complement via the mannose-binding protein (original) (raw)

References

  1. Chang, S.-C. Altered Glycosylation in Immunoglobulin G and Its Fragments in Rheumatoid Arthritis. thesis, Oxford (1993).
  2. Parekh, R.B. et al. Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG. Nature 316, 452–457 (1985).
    Article CAS Google Scholar
  3. Parekh, R.B. et al. A comparative analysis of disease-associated changes in the galactosylation of serum IgG. J. Autoimmun. 2, 101–114 (1989).
    Article CAS Google Scholar
  4. Van Zeben, D. et al. Early agalactosylation of IgG is associated with a more progressive disease course in patients with rheumatoid arthritis: Results of a follow-up study. Br. J. Rheumatol. 33, 36–43 (1994).
    Article CAS Google Scholar
  5. Rook, G.A.W. et al. Changes in IgG glycoform levels are associated with remission of arthritis during pregnancy. J. Autoimmun. 4, 779–794 (1991).
    Article CAS Google Scholar
  6. Morgan, B.P. Complement: Clinical Aspects and Relevance to Disease (Academic Press, London, (1990).
    Google Scholar
  7. Burton, D.R. et al. The C1q receptor site on Immunoglobulin G. Nature 288, 338–344 (1980).
    Article CAS Google Scholar
  8. Duncan, A.R. & Winter, G. The binding site for C1q on IgG. Nature 332, 738–740 (1988).
    Article CAS Google Scholar
  9. Ikeda, K., Sannoh, T., Kawasaki, N., Kawasaki, T. & Yamashina, I. Serum lectin with known structure activates complement through the classical pathway. J. biol. Chem. 262, 451–454 (1987).
    Google Scholar
  10. Malhotra, R., Lu, J., Holmskov, U.S. & Sim, R.B., Collectins, collectin receptors and the lectin pathway of complement. Clin. exp. Immunol. 97, suppl. 2, 4–9 (1994).
    Article CAS Google Scholar
  11. Drickamer, K., Dordal, M.S. & Reynolds, L. Mannose binding protein isolated from rat liver contains carbohydrate-recognition domains linked to collagenous tails. Complete primary structure and homology with pulmonary surfactant apoprotein. J. biol. Chem. 261, 6878–6887 (1986).
    CAS PubMed Google Scholar
  12. Weis, W.I., Drickamer, K. & Hendrickson, W.A. Structure of a C-type mannose-binding protein complexed with an oligosaccharide. Nature 360, 127–134 (1992).
    Article CAS Google Scholar
  13. Rademacher, T.W., Williams, P. & Dwek, R.A. Agalactosyl glycoforms of IgG autoantibodies are pathogenic. Proc. natn. Acad. Sci., U.S. A. 91, 6123–6127 (1994).
    Article CAS Google Scholar
  14. Deisenhofer, J. Crystallographic refinement and atomic models of human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9 and 2.8 A resolution. Biochemistry 20, 2361–2370 (1981).
    Article CAS Google Scholar
  15. Parekh, R.B. A Study of the Structure and Biosynthesis of N-linked Oligosaccharides and of their Involvement in Certain Diseases. thesis, Oxford Univ.(1987).
  16. Iobst, S.T., Wormald, M.R., Weis, W.I., Dwek, R.A. & Drickamer, K. Binding of sugar ligands to Ca2+-dependent animal lectins : I. Analysis of mannose binding by site-directed mutagenesis and NMR. J. biol. Chem. 269, 15505–15511 (1994).
    CAS PubMed Google Scholar
  17. Sjoholm, A.G., Selander, B., Ostenson, S., Holmstrom, E. & Soderstrom, C. Normal human serum depleted of C1q, factor D and properdin: its use in studies of complement activation. APMIS 99, 1120–1128 (1991).
    Article CAS Google Scholar
  18. Rademacher, T.W. et al. The role of IgG glycoforms in the pathogenesis of rheumatoid arthritis. Springer Semin. Immunopathology 10, 231–249 (1988).
    Article CAS Google Scholar
  19. Tsuchiya, N. et al. Detection of glycosylation abnormality in rheumatoid IgG using N-acetylglucosamine-specific Psathyrella velutina lectin. J. Immun. 151, 1137–1146 (1993).
    CAS PubMed Google Scholar
  20. Sherrif, S., Chang, C.Y. & Ezekowitz, R.A.B. Human mannose-binding protein carbohydrate recognition domain trimerizes through a triple α-helical coiled-coil. Nature struct. Biol. 11, 789–794 (1994).
    Article Google Scholar
  21. Weis, W.I. & Drickamer, K. Trimeric structure of a C-type mannose-binding protein. Structure 2, 1227–1240 (1994).
    Article CAS Google Scholar
  22. Meiboom, S. & Gill, D. Modified spin-echo method for measuring nuclear relaxation times. Rev. Sci. Instrum. 29, 688–691 (1958).
    Article CAS Google Scholar
  23. Ashford, A. et al. The β1-2-D-xylose and α1-3-L-fucose substituted N-linked oligosaccharides from Erythrina cristagalli lectin. Isolation, characterisation and comparison with other legume lectins. Eur. J. Biochem. 166, 311–320 (1987).
    Article CAS Google Scholar
  24. Parekh, R.B., Tse, A.G.D., Dwek, R.A., Williams, A.F. & Rademacher, T.W., Tissue-specific N-glycosylation, site-specific oligosaccharide patterns and lentil lectin recognition of rat Thy-1. Eur. molec. Biol. Org. J. 6, 1233–1244 (1987).
    Article CAS Google Scholar
  25. Parekh, R.B., Isenberg, D.A., Roitt, I.M., Dwek, R.A. & Rademacher, T.R. Age-related galactosylation of the N-linked oligosaccharides of human serum IgG. J. exp. Med. 167, 1713–1736 (1988).
    Article Google Scholar
  26. Porter, R.R. The hydrolysis of rabbit γ-globulin and antibodies with crystalline papain. Biochem. J. 73, 119–126 (1959).
    CAS PubMed PubMed Central Google Scholar
  27. Kiyohara, T., Terao, T., Shioiri-Nakano, K. & Osawa, T. Purification and characterisation of β-_N_-acetylhexosaminidases and β-galactosidase from Streptococcus 6646 K. Jap. J. Biochem. 80, 9–17 (1976).
    Article CAS Google Scholar
  28. Super, M. et al. Distinct and overlapping functions of allelic forms of human mannose-binding protein. Nature Genet. 2, 50–55 (1992).
    Article CAS Google Scholar
  29. Malhotra, R., Willis, A.C., Bernal, L.A., Thiel, S. & Sim, R.B. Mannan-binding protein levels in human amniotic fluid during gestation and its interaction with collectin receptor from amnion cells. Immunology 84, 439–444 (1994).
    Google Scholar
  30. Rademacher, T.W., Homans, S.W., Parekh, R.B. & Dwek, R.A. Immunoglobulin G as a glycoprotein. Biochem. Soc. Symp. 51, 131–148 (1986).
    CAS PubMed Google Scholar
  31. Dwek, R.A., Sutton, B.J., Perkins, S.J. & Rademacher, T. W. Structure-function relationships in immunoglobulins. Biochem. Soc. Symp. 49, 123–136 (1984).
    CAS PubMed Google Scholar
  32. Malhotra, R., Thiel, S., Reid, K.B.M. & Sim, R.B. Human leukocyte C1q receptor binds other soluble proteins with collagen domains. J. exp. Med. 172, 955–959 (1990).
    Article CAS Google Scholar

Download references