p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3 (original) (raw)

• Vogelstein, B. & Kinzler, K.W. . p53 function and dysfunction. Cell 70, 523–526 (1992).
  CAS PubMed Google Scholar
• Chen, L.-C. et al. Loss of heterozygosity on the short arm of chromosome 17 is associated with high proliferative capacity and DNA aneuploidy in primary human breast cancer. Proc. natn. Acad. Sci. U.S.A. 88, 3847–3851 (1991).
  CAS Google Scholar
• Takita, K.-I. et al. Correlation of loss of alleles on the short arm of chromosomes 11 and 17 with metastasis of primary breast cancer to lymph nodes. Cancer Res. 52, 3914–3917 (1992).
  CAS PubMed Google Scholar
• Deng, G. et al. Loss of heterozygosity and p53 gene mutations in breast cancer. Cancer Res. 54, 499–505 (1994).
  CAS PubMed Google Scholar
• Cornelis, R.S. et al. Evidence for a gene on 17p13.3, distal to TP53, as a target for allele loss in breast tumors without p53 mutations. Cancer Res. 54, 4200–4206 (1994).
  CAS PubMed Google Scholar
• Coles, C. et al. Evidence implicating at least two genes on chromosome 17p in breast carcinogenesis. Lancet 336, 761–763 (1990).
  CAS PubMed Google Scholar
• Makos, M. et al. Distinct hypeimethylation patterns occur at altered chromosome loci in human lung and colon cancer. Proc. natn. Acad. Sci. U.S.A. 89, 1929–1933 (1992).
  CAS Google Scholar
• Makos, M. et al. DNA hypermethylation is associated with 17p allelic loss in neural tumors. Cancer Res. 53, 2715–2718 (1993).
  CAS PubMed Google Scholar
• Makos, M. et al. Regional DNA hypermethylation at D17S5 precedes 17p structural changes in the progression of renal tumors. Cancer Res. 53, 2719–2722 (1993).
  CAS PubMed Google Scholar
• Baylin, S.B. et al. Abnormal patterns of DNA methylation in human neoplasia: Potential consequences fortumorprogression. Cancer Cells 3, 383–390 (1991).
  CAS PubMed Google Scholar
• Jones, P.A. & Buckley, J.D. The role of DNA methylation in cancer. Adv. Cancer Res. 54, 1–23 (1990).
  CAS PubMed Google Scholar
• Herman, J.G. et al. Silencing of the VHL tumor suppressor gene by DNA methylation in renal carcinoma. Proc. natn. Acad. Sci. 91, 9700–9704 (1994).
  CAS Google Scholar
• Ottaviano, Y.L. et al. Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res. 54, 2552–2555 (1994).
  CAS PubMed Google Scholar
• Issa, J.-P.J. et al. Methylation of the estrogen receptor CpG island links aging and neoplasia in human colon. Nature Genet. 7, 536–540 (1994).
  CAS PubMed Google Scholar
• Steenman, M.J.C. et al. Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour. Nature Genet. 7, 433–439 (1994).
  CAS PubMed Google Scholar
• Ledbetter, D.H. et al. Molecular dissection of a contiguous gene syndrome: Frequent submicroscopic deletions, evolutionarily conserved sequences, and a hypomethylated “island” in the Miller-Dicker chromosome region. Proc. natn. Acad. Sci. U.S.A. 86, 5136–5140 (1989).
  CAS Google Scholar
• Gish, W. & States, D.J. Identification of protein coding regions by database similarity search. Nature Genet. 3, 266–272 (1993).
  CAS PubMed Google Scholar
• Altschul, S.F., Gish, W., Miller, W., Myers, E.W. & Lipman, D.J. Basic local alignment search tool. J. molec. Biol. 215, 403–410 (1990).
  CAS PubMed Google Scholar
• Numoto, M. et al. Transcriptional represser ZF5 identifies a new conserved domain in zinc finger proteins. Nucleic Acids Res. 21, 3767–3775 (1993).
  CAS PubMed PubMed Central Google Scholar
• Harrison, S.D. & Travers, A.A. The tramtrack gene encodes a drosophila finger protein that interacts with the ftz transcriptional regulatory region and shows a novel embryonic expression pattern. EMBO J. 9, 207–216 (1990).
  CAS PubMed PubMed Central Google Scholar
• DiBello, P.R., Withers, D.A., Bayer, C.A., Fristrom, J.W. & Guild, G.M. The drosophila broad-complex encodes a family of related proteins containing zinc fingers. Genetics 129, 385–397 (1991).
  CAS PubMed PubMed Central Google Scholar
• Chardin, P., Courtois, G., Mattei, M.-G. & Gisselbrecht, S. The KUP gene, located on human chromosome 14, encodes a protein with two distant zinc fingers. Nucleic Acids Res. 19, 1431–1436 (1991).
  CAS PubMed PubMed Central Google Scholar
• Hromas, R. et al. A retinoic acid-responsive human zinc finger gene, MZF-1, preferentially expressed in myeloid cells. J. biol. Chem. 266, 14183–14187 (1991).
  CAS PubMed Google Scholar
• Chen, Z. et al. Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-α locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia. EMBO J. 12, 1161–11671 (1993).
  CAS PubMed PubMed Central Google Scholar
• Kerckaert, J.-P., Deweindt, C., Tilly, H., Quief, S., Lecocq, G. & Bastard, C. LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas. Nature Genet. 5, 66–70 (1993).
  CAS PubMed Google Scholar
• Ye, B.H. et al. Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma. Science 262, 747–750 (1993).
  CAS PubMed Google Scholar
• Soeller, W.C., Oh, C.E. & Kornberg, T.B. Isolation of cDNAs encoding the drosophila GAGA transcription factor. Molec. cell. Biol. 13, 7961–7970 (1993).
  CAS PubMed Google Scholar
• Ruppert, J.M. et al. The GLI-Kruppel family of human genes. Molec. cell. Biol. 8, 3104–3113 (1988).
  CAS PubMed Google Scholar
• El-Deiry, W.S., Kern, S.E., Pietenpol, J.A., Kinzler, K.W. & Vogelstein, B. Definition of a consensus binding site for p53. Nature Genet. 1, 45–49 (1992).
  CAS PubMed Google Scholar
• Kern, S.E. et al. Identification of p53 as a sequence-specific DNA-binding protein. Science 252, 1708–1711 (1991).
  CAS PubMed Google Scholar
• Funk, W.D., Pak, D.T., Karas, R.H., Wright, W.E. & Shay, J.W. A transcriptionally active DNA-binding site for human p53 protein complexes. Molec. cell. Biol. 12, 2866–2871 (1992).
  CAS PubMed Google Scholar
• El-Deiry, W.S. et al. WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817–825 (1993).
  CAS Google Scholar
• Baker, S.J., Markowitz, S., Fearon, E.R., Willson, J.K.V. & Vogelstein, B. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 249, 912–915 (1990).
  CAS PubMed Google Scholar
• Riggs, A.D. & Pfeifer, G.D. X-chromosome inactivation and cell memory. Trends Genet. 8, 169–174 (1992).
  CAS PubMed Google Scholar
• Li, E., Beard, C. & Jaenisch, R. Role for DNA methylation in genomic imprinting. Nature 366, 362–365 (1993).
  CAS PubMed Google Scholar
• Yisraeli, J. et al. Muscle specific activation of a methylated chimeric actin gene. Cell 46, 409–416 (1986).
  CAS PubMed Google Scholar
• Runnebaum, I.B., Nagarajan, M., Bowman, M., Soto, D. & Sukumar, S. Mutations in p53 as potential molecular markers for human breast cancer. Proc. natn. Acad. Sci. U.S.A. 88, 10657–10661 (1991).
  CAS Google Scholar
• Negrini, M. et al. Tumor and growth suppression of breast cancer cells by chromosome 17-associated functions. Cancer Res. 54, 1818–1824 (1994).
  CAS PubMed Google Scholar
• Chen, P., Ellmore, N. & Weissman, B.E. Functional evidence for a second tumor suppressor gene on human chromosome 17. Molec. cell. Biol. 14, 534–542 (1994).
  CAS PubMed Google Scholar
• Hensel, C.H., Xiang, R.H., Sakaguchi, A.Y. & Naylor, S.L. Use of the single strand conformation polymorphism technique and PCR to detect p53 gene mutations in small cell lung cancer. Oncogene 6, 1067–1071 (1991).
  CAS PubMed Google Scholar
• Baker, S.J. et al. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res. 50, 7717–7722 (1990).
  CAS PubMed Google Scholar
• Van Meir, E.G. et al. Analysis of the p53 gene and its expression in human glioblastoma cells. Cancer Res. 54, 649–652 (1994).
  CAS PubMed Google Scholar
• Chen, C.Y. et al. Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway. Proc. natn. Acad. Sci. U.S.A. 91, 2684–2688 (1994).
  CAS Google Scholar
• Kastan, M.B. et al. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 71, 587–597 (1992).
  CAS PubMed Google Scholar
• Miyashita, T. et al. Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9, 1799–1805 (1994).
  CAS Google Scholar
• Tsukiyama, T., Becker, P.B. & Wu, C. ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor. Nature 367, 525–532 (1994).
  CAS PubMed Google Scholar
• Bardwell, V.J. & Treisman, R. The POZ domain: A conserved protein-protein interaction motif. Genes Dev. 8, 1664–1677 (1994).
  CAS PubMed Google Scholar
• Miki, T., Kawamata, N., Hirosawa, S. & Aoki, N. Gene involved in the 3q27 translocation associated with B-cell lymphoma, BCL5, encodes a Kruppel-like zinc-finger protein. Blood 83, 26–32 (1994).
  CAS PubMed Google Scholar
• Carney, D.N., Bepler, G. & Gazdar, A.F. The serum-free establishment and in vitro growth properties of classic and variant small cell lung cancer cell lines. Recent Results Cancer Res. 99, 157–166 (1985).
  CAS PubMed Google Scholar