Common origins of lung cancer and COPD (original) (raw)

Nature Medicine volume 14, pages 1023–1024 (2008)Cite this article

Smoke is a solid. Whether from cigarettes, cooking fires or other sources, it is comprised of tiny particles that injure the lung and can lead to lung cancer and chronic obstructive pulmonary disorder, characterized by laborious breathing. Steven D. Shapiro and his colleagues take a look at imaging data in people suggesting that these two conditions have more in common mechanistically than was previously thought. Both diseases seem to stem in part from the ability of inhaled particles to trigger inflammation, a process examined by Robert M. Senior and his colleagues.

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Figure 1: Hypothesized common origins of emphysema and lung cancer.

Kim Caesar

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Authors and Affiliations

  1. Majd Mouded and Steven D. Shapiro are in the Department of Medicine, Division of Pulmonary, A. McGarry Houghton, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA. sds33@pitt.edu,
    A McGarry Houghton, Majd Mouded & Steven D Shapiro

Authors

  1. A McGarry Houghton
  2. Majd Mouded
  3. Steven D Shapiro

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Houghton, A., Mouded, M. & Shapiro, S. Common origins of lung cancer and COPD.Nat Med 14, 1023–1024 (2008). https://doi.org/10.1038/nm1008-1023

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