Donor-specific B-cell tolerance after ABO-incompatible infant heart transplantation (original) (raw)

References

  1. Alexandre, G.P. et al. Present experiences in a series of 26 ABO-incompatible living donor renal allografts. Transplant. Proc. 19, 4538–4542 (1987).
    CAS Google Scholar
  2. Sutherland, D.E. et al. Long-term effect of splenectomy versus no splenectomy in renal transplant patients. Reanalysis of a randomized prospective study. Transplantation 38, 619–624 (1984).
    Article CAS Google Scholar
  3. Bannett, A.D., McAlack, R.F., Morris, M., Chopek, M.W. & Platt, J.L. ABO incompatible renal transplantation: a qualitative analysis of native endothelial tissue ABO antigens after transplantation. Transplant. Proc. 21, 783–785 (1989).
    CAS Google Scholar
  4. Chopek, M.W., Simmons, R.L. & Platt, J.L. ABO-incompatible kidney transplantation: initial immunopathologic evaluation. Transplant. Proc. 19, 4553–4557 (1987).
    CAS Google Scholar
  5. Cooper, D.K. A clinical survey of cardiac transplantation between ABO blood group-incompatible recipients and donors. Transplant Proc. 22, 1457 (1990).
    CAS Google Scholar
  6. Gugenheim, J., Samuel, D., Reynes, M. & Bismuth, H. Liver transplantation across ABO blood group barriers. Lancet 336, 519–523 (1990).
    Article CAS Google Scholar
  7. Owen, R.D. Immunogenetic consequences of vascular anastomoses between bovine twins. Science 102, 400–405 (1945).
    Article CAS Google Scholar
  8. Burnet, F.M. & Fenner, F. The Production of Antibodies. (Macmillan and Company, Melbourne, 1949).
    Google Scholar
  9. Billingham, R.E., Brent, L. & Medawar, P.B. Activity acquired tolerance of foreign cells. Nature 172, 603–606 (1953).
    Article CAS Google Scholar
  10. Dorsch, S. & Roser, B. Suppressor cells in transplantation tolerance. I. Analysis of the suppressor status of neonatally and adoptively tolerized rats. Transplantation 33, 518–524 (1982).
    Article CAS Google Scholar
  11. Kappler, J.W., Roehm, N. & Marrack, P. T cell tolerance by clonal elimination in the thymus. Cell 49, 273–280 (1987).
    Article CAS Google Scholar
  12. Klinman, N.R. The “clonal selection hypothesis” and current concepts of B cell tolerance. Immunity 5, 189–195 (1996).
    Article CAS Google Scholar
  13. McCarthy, S.A. & Bach, F.H. The cellular mechanism of maintenance of neonatally induced tolerance to H-2 class I antigens. J. Immunol. 131, 1676–1682 (1983).
    CAS Google Scholar
  14. Ramsdell, F. & Fowlkes, B.J. Clonal deletion versus clonal anergy: the role of the thymus in inducing self tolerance. Science 248, 1342–1348 (1990).
    Article CAS Google Scholar
  15. Ramsdell, F., Lantz, T. & Fowlkes, B.J. A nondeletional mechanism of thymic self tolerance. Science 246, 1038–1041 (1989).
    Article CAS Google Scholar
  16. Streilein, J.W. Neonatal tolerance of H-2 alloantigens. Procuring graft acceptance the “old-fashioned” way. Transplantation 52, 1–10 (1991).
    Article CAS Google Scholar
  17. West, L.J. Defining critical windows in the development of the human immune system. Hum. Exp. Toxicol. 21, 499–505 (2002).
    Article CAS Google Scholar
  18. West, L.J. Developmental aspects of immunomodulation: exploiting the immature immune system for organ transplantation. Transpl. Immunol. 9, 149–153 (2002).
    Article CAS Google Scholar
  19. Cadoz, M. Potential and limitations of polysaccharide vaccines in infancy. Vaccine 16, 1391–1395 (1998).
    Article CAS Google Scholar
  20. Gennery, A.R. et al. Effect of immunosuppression after cardiac transplantation in early childhood on antibody response to polysaccharide antigen. Lancet 351, 1778–1781 (1998).
    Article CAS Google Scholar
  21. Wilson, C.B. Immunologic basis for increased susceptibility of the neonate to infection. J. Pediatr. 108, 1–12 (1986).
    Article CAS Google Scholar
  22. Fong, S.W., Qaqundah, B.Y. & Taylor, W.F. Developmental patterns of ABO isoagglutinins in normal children correlated with the effects of age, sex., and maternal isoagglutinins. Transfusion 14, 551–559 (1974).
    Article CAS Google Scholar
  23. Springer, G.F. & Horton, R.E. Blood group isoantibody stimulation in man by feeding blood group-active bacteria. J. Clin. Invest. 48, 1280–1291 (1969).
    Article CAS Google Scholar
  24. West, L.J. et al. ABO-incompatible heart transplantation in infants. N. Engl. J. Med. 344, 793–800 (2001).
    Article CAS Google Scholar
  25. Smalley, C.E. & Tucker, E.M. Blood group A antigen site distribution and immunoglobulin binding in relation to red cell age. Br. J. Haematol. 54, 209–219 (1983).
    Article CAS Google Scholar
  26. Mollison, P.L., Contreras, M. & Engelfriet, C.P. ABO, Lewis, Ii and P groups. in Blood Transfusion in Clinical Medicine. 9th edn 155 (Blackwell Scientific Publishing, Oxford, 1993).
    Google Scholar
  27. Hamano, K., Rawsthorne, M.A., Bushell, A.R., Morris, P.J. & Wood, K.J. Evidence that the continued presence of the organ graft and not peripheral donor microchimerism is essential for maintenance of tolerance to alloantigen in vivo in anti-CD4 treated recipients. Transplantation 62, 856–860 (1996).
    Article CAS Google Scholar
  28. Morecki, S., Leshem, B., Eid, A. & Slavin, S. Alloantigen persistence in induction and maintenance of transplantation tolerance. J. Exp. Med. 165, 1468–1480 (1987).
    Article CAS Google Scholar
  29. Erikson, J., Radic, M.Z., Camper, SA., Hardy, R.R., Carmack, C. & Weigert, M. Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice. Nature 349, 331–334 (1991).
    Article CAS Google Scholar
  30. Goodnow, C.C. et al. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature 334, 676–682 (1988).
    Article CAS Google Scholar
  31. Chelvarajan, R.L., Gilbert, N.L. & Bondada, S. Neonatal murine B lymphocytes respond to polysaccharide antigens in the presence of IL-1 and IL-6. J. Immunol. 161, 3315–3324 (1998).
    CAS Google Scholar
  32. Luo, W., Fine, J., Garg, M., Kaplan, A.M. & Bondada, S. Interleukin-10 enhances immune responses to pneumococcal polysaccharides and sheep erythrocytes in young and aged mice. Cell Immunol. 195, 1–9 (1999).
    Article CAS Google Scholar
  33. Splawski, J.B. & Lipsky, P.E. Cytokine regulation of immunoglobulin secretion by neonatal lymphocytes. J. Clin. Invest. 88, 967–977 (1991).
    Article CAS Google Scholar
  34. Galili, U. Interaction of the natural anti-Gal antibody with alpha-galactosyl epitopes: a major obstacle for xenotransplantation in humans. Immunol. Today 14, 480–482 (1993).
    Article CAS Google Scholar
  35. Chen, C. et al. The site and stage of anti-DNA B-cell deletion. Nature 373, 252–255 (1995).
    Article CAS Google Scholar
  36. Hartley, S.B., Crosbie, J., Brink, R., Kantor, A.B., Basten, A. & Goodnow, C.C. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature 353, 765–769 (1991).
    Article CAS Google Scholar
  37. Nemazee, D.A. & Burki, K. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature 337, 562–566 (1989).
    Article CAS Google Scholar
  38. Gay, D., Saunders, T., Camper, S. & Weigert, M. Receptor editing: an approach by autoreactive B cells to escape tolerance. J. Exp. Med. 177, 999–1008 (1993).
    Article CAS Google Scholar
  39. Radic, M.Z., Erikson, J., Litwin, S. & Weigert, M. B lymphocytes may escape tolerance by revising their antigen receptors. J. Exp. Med. 177, 1165–1173 (1993).
    Article CAS Google Scholar
  40. Tiegs, S.L., Russell, D.M. & Nemazee, D. Receptor editing in self-reactive bone marrow B cells. J. Exp. Med. 177, 1009–1020 (1993).
    Article CAS Google Scholar
  41. Hammarstrom, L. & Smith, CI. Development of anti-polysaccharide antibodies in asplenic children. Clin. Exp. Immunol. 66, 457–462 (1986).
    CAS Google Scholar
  42. Lang, J. & Nemazee, D. B cell clonal elimination induced by membrane-bound self-antigen may require repeated antigen encounter or cell competition. Eur. J. Immunol. 30, 689–696 (2000).
    Article CAS Google Scholar
  43. Wang, C., Sun, J., Sheil, A.G., McCaughan, G.W. & Bishop, G.A. A short course of methylprednisolone immunosuppression inhibits both rejection and spontaneous acceptance of rat liver allografts. Transplantation 72, 44–51 (2001).
    Article CAS Google Scholar
  44. Perico, N., Imberti, O., Bontempelli, M. & Remuzzi, G. Immunosuppressive therapy abrogates unresponsiveness to renal allograft induced by thymic recognition of donor antigens. J. Am. Soc. Nephrol. 5, 1618–1623 (1995).
    CAS Google Scholar
  45. Yamada, K. et al. Role of the thymus in transplantation tolerance in miniature swine. I. Requirement of the thymus for rapid and stable induction of tolerance to class I-mismatched renal allografts. J. Exp. Med. 186, 497–506 (1997).
    Article CAS Google Scholar
  46. Noris, M. et al. Thymic microchimerism correlates with the outcome of tolerance-inducing protocols for solid organ transplantation. J. Am. Soc. Nephrol. 12, 2815–2826 (2001).
    CAS Google Scholar
  47. Nakafusa, Y., Goss, J.A. & Flye, M.W. Prevention by thymectomy of tolerance induced by intrathymic injection of donor splenocytes. Surgery 114, 183–189 (1993).
    CAS Google Scholar
  48. Mond, J.J., Lees, A. & Snapper, C.M. T cell-independent antigens type 2. Annu. Rev. Immunol. 13, 655–692 (1995).
    Article CAS Google Scholar
  49. Holsapple, M.P., West, L.J. & Landreth, K.S. Species comparison of anatomical and functional immune system development. Birth Defects Res. Part B Dev. Reprod. Toxicol. 68, 321–334 (2003).
    Article CAS Google Scholar
  50. Lin, S.S. et al. The role of anti-Galalpha1-3Gal antibodies in acute vascular rejection and accommodation of xenografts. Transplantation 70, 1667–1674 (2000).
    Article CAS Google Scholar

Download references