Impact of the cyclin–dependent kinase inhibitor p27Kip1 on resistance of tumor cells to anticancer agents (original) (raw)

• Tannock, I. Cell kinetics and chemotherapy: A critical review. Cancer Treat Rep. 62, 1117–1133 (1978).
  CAS PubMed Google Scholar
• Tannock, I.F. Principles of cell proliferation: Cell kinetics. in: Current Cancer Therapeutics. (eds. Kirkwood, J.M., Lotze, M.T. & Yasko, J.M.) 3–13 (Princeton Academic Press, Princeton, New Jersey, 1994).
  Google Scholar
• Sutherland, R.M. Cell and environment interactions in tumor microregions: The multicell spheroid model. Science 240, 177–184 (1988).
  Article CAS Google Scholar
• Olive, P.L. & Durand, R.E. Drug and radiation resistance in spheroids Cell contact and kinetics. Cancer Metastasis Rev. 13, 121–138 (1994).
  Article CAS Google Scholar
• Teicher, B.A. et al. Tumor resistance to alkylating agents conferred by mechanisms operative only in vivo. Science 247, 1457–1461 (1990).
  Article CAS Google Scholar
• Kobayashi, H., Man, S., Kapitain, S.J., Teicher, B.A. & Kerbel, R.S. Acquired multicellular-mediated resistance to alkylating agents in cancer. Proc. Natl. Acad. Sci. USA 90, 3294–3298 (1993).
  Article CAS Google Scholar
• St Croix, B. et al. Reversal by hyaluronidase of adhesion-dependent multicellular drug resistance in mammary carcinoma cells. J. Natl. Cancer Inst. 88, 1285–1296 (1996).
  Article CAS Google Scholar
• Kerbel, R.S. et al. Multicellular resistance: A new paradigm to explain aspects of acquired drug resistance of solid tumors. Cold. Spring. Harbor. Symp. Quant. Biol. 59, 661–672 (1994).
  Article CAS Google Scholar
• Hoffman, R.M. The three-dimensional question: Can clinically relevant tumor drug resistance be measured in vitro? Cancer Metastasis Rev. 13, 169–173 (1994).
  Article CAS Google Scholar
• Morgan, D.O. Principles of CDK regulation. Nature 374, 131–134 (1995).
  Article CAS Google Scholar
• Sherr, C.J. & Roberts, J.M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9, 1149–1163
  Article CAS Google Scholar
• Hunter, T. & Pines, J. Cyclins and cancer. II. Cyclin D and CDK inhibitors come of age. Cell 79 573–582 (1994).
  Article CAS Google Scholar
• Ponce-Castaneda, M.V. et al p27 kip1 : Chromosomal mapping to 12pl2-12pl3.1 and absence of mutations in human tumors. Cancer Res. 55, 1211–1214 (1995).
  CAS PubMed Google Scholar
• Kawamata, N. et al. Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies. Cancer Res. 55, 2266–2269 (1995).
  CAS PubMed Google Scholar
• Shiohara, M. et al. Absence of WAF1 mutations in a variety of human malignancies. Blood 84, 3781–3784 (1994).
  CAS PubMed Google Scholar
• Ferrando, A.A. et al. Mutational analysis of the human cyclin-dependent kinase inhibitor p27kip1in primary breast carcinomas. Hum Genet. 97, 91–94 (1996).
  Article CAS Google Scholar
• Spirin, K.S. et al. p27/Kip1 mutation found in breast cancer. Cancer Res. 56, 2400–2404 (1996).
  CAS PubMed Google Scholar
• Slingerland, J.M. et al. A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor (β-arrested epithelial cells. Mol. Cell. Biol. 14, 3683–3694 (1994).
  Article CAS Google Scholar
• Hengst, L., Dulic, V., Slingerland, J.M., Lees, E. & Reed, S.I. A cell cycle-regulated inhibitor of cyclin-dependent kinases. Proc Natl. Acad. Sci. USA 91, 5291–5295 (1994).
  Article CAS Google Scholar
• Polyak, K. et al. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev. 8, 9–22 (1994).
  Article CAS Google Scholar
• Wagner, R.W. et al. Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines. Science 260, 1510–1513 (1993).
  Article CAS Google Scholar
• Coats, S., Flanagan, W.M., Nourse, J. & Roberts, J.M. Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle. Science 272 877–880 (1996).
  Article CAS Google Scholar
• Reyniskottir, I., Polyak, K. Iavarone, A. & Massague, J. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β Genes Dev. 9 1831–1845 (1995).
  Article Google Scholar
• Conte, P.F. et al. Conventional versus cytokinetic polychemotherapy with estrogenic recruitment in metastatic breast cancer: Results of a randomized cooperative trial. J. Clin. Oncol. 5, 339–347 (1987).
  Article CAS Google Scholar
• Gore, S.D. et al. Impact of in vivo administration of interleukin 3 on proliferation, differentiation, and chemosensitivity of acute myeloid leukemia. Clin. Cancer Res. 1, 295–303 (1995).
  CAS PubMed Google Scholar
• Karp, J.E. & Broder, S. Molecular foundations of cancer: New targets for intervention. Nature Med. 1, 309–320 (1995).
  Article CAS Google Scholar
• Fang, F., Orend, G., Watanabe, N., Hunter, T. & Ruoslahti, E. Dependence of cyclin E-Cdk2 kinase activity on cell anchorage. Science 271, 499–502 (1996).
  Article CAS Google Scholar
• Sano, Y., Hoshino, T., Bjerkvig, R. & Deen, D.F. The relative resistance of non-cycling cells in 9L multicellular spheroids to spirohydantoin mustard. Eur. J. Cancer Clin. Oncol. 19, 1451–1456 (1983).
  Article CAS Google Scholar
• Hinz, G. & Dertinger, H. Increased radioresistance of cells in cultured multicell spheroids. Radiat Environ Biophys. 21, 255–264 (1983).
  Article CAS Google Scholar
• Remvikos, Y. et al. Cell cycle modifications of breast cancers during neoadjuvant chemotherapy: A flow cytometry study on fine needle aspirates. Eur. J. Cancer 29A 1843–1848 (1993).
  Article CAS Google Scholar
• Briffod, M. et al. Evaluation of breast carcinoma chemosensitivity by flow cyto-metric DNA analysis and computer assisted image analysis. Cytometry 13, 250–258 (1992).
  Article CAS Google Scholar
• Spyratos, F. et al. Sequential cytopunctures during preoperative chemotherapy for primary breast carcinoma. Cancer 69, 470–475 (1992).
  Article CAS Google Scholar
• Meredith, J.E. Jr., Fazeli, B. & Schwartz, M.A. The extra cellular matrix as a cell survival factor. Mol. Biol. Cell 4, 953–961 (1993).
  Article CAS Google Scholar
• Frisch, S.M. & Francis, H. Disruption of epithelial cell-matrix interactions induces apoptosis. J. Cell. Rial. 124, 619–626 (1994).
  Article CAS Google Scholar
• Bates, R.C., Buret, A. van Helden, D.F., Horton, M.A. & Burns, G.F. Apoptosis induced by inhibition of inter cellular contact. J. Cell Biol. 125, 403–415 (1994).
  Article CAS Google Scholar
• Mendonca, M.S., Rodriguez, A. & Alpen, E.L. Differential repair of potentially lethal damage in exponentially growing and quiescent 9L Cells. Rad. Res. 122, 38–43 (1990).
  Article CAS Google Scholar
• Little, J.B., Hahn, G.M., Frindel, E. & Tubiana, M. Repair of potentially lethal radiation damage in vitro and in vivo . Radiology 106, 689–694 (1973).
  Article CAS Google Scholar
• Dimanche-Boitrel, M.-T., Garrido, C. & Chauffert, B. Kinetic resistance to anticancer agents. Cytotechnology 12, 347–356 (1993).
  Article CAS Google Scholar
• Dimanche-Boitrel, M. et al. Confluence-dependent resistance in human colon cancer cells: Role of reduced drug accumulation and low intrinsic chemosensitivity of resting cells. Int. J. Cancer 50, 677–682 (1992).
  Article CAS Google Scholar
• Zhang, W. et al. High levels of constitutive WAFl/Cipl protein are associated with chemoresistance in acute myelogenous leukemia. Clin. Cancer Res. 1, 1051–1057 (1995).
  CAS PubMed Google Scholar
• Poluha, W. et al. The cyclin-dependent kinase inhibitor p21WAF1 is required for survival of differentiating neuroblastoma cells. Mol. Cell. Biol. 16, 1335–1341 (1996).
  Article CAS Google Scholar
• Waldman, T., Lengauer, C., Kinzler, K.W. & Vogelstein, B. Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381, 713–716 (1996).
  Article CAS Google Scholar
• Wang, J. & Walsh, K. Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation. Science 273, 359–361 (1996).
  Article CAS Google Scholar
• Deng, C., Zhang, P., Harper, J.W., Elledge, S.J. & Leder, P. Mice lacking p21CIP1/WAF1undergo normal development, but are defective in Gl checkpoint control. Cell 82, 675–684 (1995).
  Article CAS Google Scholar
• Nakayama, K. et al. Mice lacking p27kip1display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85, 707–720 (1996).
  Article CAS Google Scholar
• Kiyokawa, H. et al. Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27kip1 . Cell 85, 721–732 (1996).
  Article CAS Google Scholar
• Fero, M.L. et al. A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27kip1-deficient mice. Cell 85, 733–744 (1996).
  Article CAS Google Scholar
• Tonkinson, J.L. & Stein, C.A. Antisense oligodeoxynucleotides as clinical therapeutic agents. Cancer Invest. 14 (1), 54–65 (1996).
  Article CAS Google Scholar
• Hietanen, P. et al. Do DNA ploidy and S-phase fraction in primary tumour predict the response to chemotherapy in metastatic breast cancer. Br. J. Cancer 71, 1029–1032 (1995).
  Article CAS Google Scholar
• O'Reilly, S.M., Camplejohn, R.S., Rubens, R.D. & Richards, M.A. DNA flow cytometry and response to preoperative chemotherapy for primary breast cancer. Eur. J. Cancer 213, 681–683 (1992).
  Article Google Scholar
• Remvikos, Y. et al. Correlation of pretreatment proliferative activity of breast cancer with the response to cytotoxic chemotherapy. J. Natl. Cancer Inst. 81, 1383–1387 (1989).
  Article CAS Google Scholar