Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics (original) (raw)

References

  1. National Statistics Series DH1 no. 31, Mortality Statistics (1998). The Stationery Office (UK Government), London, England.
  2. Kjelsberg, M.O., Cutler, J.A. & Dolecek, T.A. Brief description of the Multiple Risk Factor Intervention Trial. Am. J. Clin. Nutr. 65 (Suppl. 1), 191S–195S (1997).
    Article CAS Google Scholar
  3. Kuller, L.H. et al. Cigarette smoking and mortality. MRFIT Research Group. Prev. Med. 20, 638–654 (1991).
    Article CAS Google Scholar
  4. Multiple Risk Factor Intervention Trial Research Group. Relationship between baseline risk factors and coronary heart disease and total mortality in the Multiple Risk Factor Intervention Trial. Prev. Med. 15, 254–273 (1986).
  5. McIlvain, H.E., McKinney, M.E., Thompson, A.V. & Todd, G.L. Application of the MRFIT smoking cessation program to a healthy, mixed-sex sample. Am. J. Prev. Med. 8, 165–170 (1992).
    Article CAS Google Scholar
  6. Ross, R. Atherosclerosis—an inflammatory disease. N. Engl. J. Med. 340, 115–126 (1999).
    Article CAS Google Scholar
  7. Cullen, P., Funke, H., Schulte, H. & Assmann, G. Lipoproteins and cardiovascular risk—from genetics to CHD prevention. Eur. Heart J. 19 (Suppl. C), C5–C11 (1998).
    PubMed Google Scholar
  8. Isles, C.G. & Paterson, J.R. Identifying patients at risk for coronary heart disease: Implications from trials of lipid-lowering drug therapy. Q.J. Med. 93, 567–574 (2000).
    Article CAS Google Scholar
  9. Nicholson, J.K., Lindon, J.C. & Holmes, E. 'Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 29, 1181–1189 (1999).
    Article CAS Google Scholar
  10. Nicholson, J.K. & Wilson, I.D. High resolution proton magnetic resonance spectroscopy of biological fluids Prog. Nucl. Magn. Reson. Spectrosc. 21, 449–501 (1989).
    Article CAS Google Scholar
  11. Lindon, J.C., Holmes, E. & Nicholson, J.K. Pattern recognition methods and applications in biomedical magnetic resonance. Prog. Nucl. Magn. Reson. Spectrosc. 39, 1–40 (2001).
    Article CAS Google Scholar
  12. Lindon, J.C., Nicholson, J.K.N., Holmes, E. & Everett, J.R. Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts Magn. Reson. 12, 289–320 (2000).
    Article CAS Google Scholar
  13. Holmes, E. et al. Chemometric models for toxicity classification based on NMR spectra of biofluids. Chem. Res. Toxicol. 13, 471–478 (1999).
    Article Google Scholar
  14. Storck, T., von Brevern, M.C., Behrens, C.K., Scheel, J. & Bach, A. Transcriptomics in predictive toxicology. Curr. Opin. Drug Discov. Devel. 5, 90–97 (2002).
    CAS PubMed Google Scholar
  15. Nicholson, J.K., Foxall, P.J., Spraul, M., Farrant, D.R. & Lindon, J.C. 750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma. Anal. Chem. 67, 793–811 (1995).
    Article CAS Google Scholar
  16. Ala-Korpela, M. 1H-NMR spectroscopy of human blood plasma. Prog. Nucl. Magn. Reson. Spectrosc. 27, 475–554 (1995).
    Article CAS Google Scholar
  17. Eriksson, L., Johansson, E., Kettanah-Wold, N. & Wold, S. Introduction to Multi and Megavariate Data Analysis Using Projection Methods (PCA and PLS-DA) (Umetrics AB, Malmo, Sweden, 1999).
    Google Scholar
  18. Wold, S., Antti, H., Lindgren, F. & Ohman, J. Orthogonal signal correction of near-infrared spectra. Chemometrics Intelligent Lab. Systems 44, 175–185 (1998).
    Article CAS Google Scholar
  19. Ala-Korpela, M., Hiltunen, Y. & Bell, J.D. Quantification of biomedical NMR data using artificial neural network analysis: Lipoprotein lipid profiles from 1H NMR data of human plasma. NMR Biomed. 8, 235–244 (1995).
    Article CAS Google Scholar
  20. Otvos, J. In Handbook of Lipoprotein Testing (eds. Rifai, N., Warnick, R. & Dominiczak, M.) 497–508 (AACC Press, Washington DC, 1997).
    Google Scholar

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