Irradiation induces neural precursor-cell dysfunction (original) (raw)

References

  1. Strother, D.R. et al. Tumors of the central nervous system. in Principles and Practice of Pediatric Oncology, 4th edn. (eds. Pizzo, P.A. & Poplack, D.G.) 751–824 (Lipincott Williams and Wilkins, Philadelphia, Pennsylvania, 2002).
    Google Scholar
  2. Surma-aho, O. et al. Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients. Neurology 56, 1285–1290 (2001).
    Article CAS Google Scholar
  3. Roman, D.D. & Sperduto, P.W. Neuropsychological effects of cranial radiation: Current knowledge and future directions. Int. J. Radiat. Oncol. Biol. Phys. 31, 983–998 (1995).
    Article CAS Google Scholar
  4. Crossen, J.R., Garwood, D., Glatstein, E. & Neuwelt, E.A. Neurobehavioral sequelae of cranial irradiation in adults: A review of radiation-induced encephalopathy. J. Clin. Oncol. 12, 627–642 (1994).
    Article CAS Google Scholar
  5. Abayomi, O.K. Pathogenesis of irradiation-induced cognitive dysfunction. Acta Oncol. 35, 659–663 (1996).
    Article CAS Google Scholar
  6. Lee, P.W., Hung, B.K., Woo, E.K., Tai, P.T. & Choi, D.T. Effects of radiation therapy on neuropsychological functioning in patients with nasopharyngeal carcinoma. J. Neurol. Neurosurg. Psychiatry 52, 488–492 (1989).
    Article CAS Google Scholar
  7. Hodges, H. et al. Late behavioural and neuropathological effects of local brain irradiation in the rat. Behav. Brain Res. 91, 99–114 (1998).
    Article CAS Google Scholar
  8. Sienkiewicz, Z.J., Haylock, R.G. & Saunders, R.D. Prenatal irradiation and spatial memory in mice: Investigation of dose-response relationship. Int. J. Radiat. Biol. 65, 611–618 (1994).
    Article CAS Google Scholar
  9. Tada, E., Parent, J.M., Lowenstein, D.H. & Fike, J.R. X-irradiation causes a prolonged reduction in cell proliferation in the dentate gyrus of adult rats. Neuroscience 99, 33–41 (2000).
    Article CAS Google Scholar
  10. Peissner, W., Kocher, M., Treuer, H. & Gillardon, F. Ionizing radiation-induced apoptosis of proliferating stem cells in the dentate gyrus of the adult rat hippocampus. Brain Res. Mol. Brain Res. 71, 61–68 (1999).
    Article CAS Google Scholar
  11. Parent, J.M., Tada, E., Fike, J.R. & Lowenstein, D.H. Inhibition of dentate granule cell neurogenesis with brain irradiation does not prevent seizure-induced mossy fiber synaptic reorganization in the rat. J. Neurosci. 19, 4508–4519 (1999).
    Article CAS Google Scholar
  12. Snyder, J.S., Kee, N. & Wojtowicz, J.M. Effects of adult neurogenesis on synaptic plasticity in the rat dentate gyrus. J. Neurophysiol. 85, 2423–2431 (2001).
    Article CAS Google Scholar
  13. Kempermann, G., Kuhn, H.G. & Gage, F.H. More hippocampal neurons in adult mice living in an enriched environment. Nature 386, 493–495 (1997).
    Article CAS Google Scholar
  14. Gould, E., Beylin, A., Tanapat, P., Reeves, A. & Shors, T.J. Learning enhances adult neurogenesis in the hippocampal formation. Nature Neurosci. 2, 260–265 (1999).
    Article CAS Google Scholar
  15. Shors, T.J. et al. Neurogenesis in the adult is involved in the formation of trace memories. Nature 410, 372–376 (2001).
    Article CAS Google Scholar
  16. Dawirs, R.R., Hildebrandt, K. & Teuchert-Noodt, G. Adult treatment with haloperidol increases dentate granule cell proliferation in the gerbil hippocampus. J. Neural Transm. 105, 317–327 (1998).
    Article CAS Google Scholar
  17. Leventhal, C., Rafii, S., Rafii, D., Shahar, A. & Goldman, S.A. Endothelial trophic support of neuronal production and recruitment from the adult mammalian subependyma. Mol. Cell Neurosci. 13, 450–464 (1999).
    Article CAS Google Scholar
  18. Vallieres, L., Campbell, I.L., Gage, F.H. & Sawchenko, P.E. Reduced hippocampal neurogenesis in adult transgenic mice with chronic astrocytic production of interleukin-6. J. Neurosci. 22, 486–492 (2002).
    Article CAS Google Scholar
  19. Calvo, W., Hopewell, J.W., Reinhold, H.S. & Yeung, T.K. Time- and dose-related changes in the white matter of the rat brain after single doses of X rays. Br. J. Radiol. 61, 1043–1052 (1988).
    Article CAS Google Scholar
  20. Sheline, G.E., Wara, W.M. & Smith, V. Therapeutic irradiation and brain injury. Int. J. Radiat. Oncol. Biol. Phys. 6, 1215–1228 (1980).
    Article CAS Google Scholar
  21. Pezner, R.D. & Archambeau, J.O. Brain tolerance unit: A method to estimate risk of radiation brain injury for various dose schedules. Int. J. Radiat. Oncol. Biol. Phys. 7, 397–402 (1981).
    Article CAS Google Scholar
  22. Marks, J.E., Baglan, R.J., Prassad, S.C. & Blank, W.F. Cerebral radionecrosis: Incidence and risk in relation to dose, time, fractionation and volume. Int. J. Radiat. Oncol. Biol. Phys. 7, 243–252 (1981).
    Article CAS Google Scholar
  23. Palmer, T.D., Willhoite, A.R. & Gage, F.H. Vascular niche for adult hippocampal neurogenesis. J. Comp Neurol. 425, 479–494 (2000).
    Article CAS Google Scholar
  24. Gundersen, H.J. et al. The new stereological tools: Dissector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS 96, 857–881 (1988).
    Article CAS Google Scholar
  25. Kuhn, H.G., Dickinson-Anson, H. & Gage, F.H. Neurogenesis in the dentate gyrus of the adult rat: Age-related decrease of neuronal progenitor proliferation. J. Neurosci. 16, 2027–2033 (1996).
    Article CAS Google Scholar
  26. Gage, F.H. et al. Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc. Natl. Acad. Sci. USA 92, 11879–11883 (1995).
    Article CAS Google Scholar
  27. Suhonen, J.O., Peterson, D.A., Ray, J. & Gage, F.H. Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo. Nature 383, 624–627 (1996).
    Article CAS Google Scholar
  28. Hong, J.H. et al. Induction of acute phase gene expression by brain irradiation. Int. J. Radiat. Oncol. Biol. Phys. 33, 619–626 (1995).
    Article CAS Google Scholar
  29. Heyser, C.J., Masliah, E., Samimi, A., Campbell, I.L. & Gold, L.H. Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain. Proc. Natl. Acad. Sci. USA 94, 1500–1505 (1997).
    Article CAS Google Scholar
  30. Louissaint, A., Rao, S., Leventhal, C. & Goldman, S.A. Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain. Neuron 34, 945–960 (2002).
    Article CAS Google Scholar
  31. Lim, D.A. et al. Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron 28, 713–726 (2000).
    Article CAS Google Scholar
  32. Seaberg, R.M. & van der Kooy, D. Adult rodent neurogenic regions: the ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors. J. Neurosci. 22, 1784–1793 (2002).
    Article CAS Google Scholar

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