AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists (original) (raw)

• Brown, D.A. M-current. in Ion Channels (ed. Narahashi, T.) 55–94 (Plenum, New York, 1988).
  Chapter Google Scholar
• Marrion, N.V. Control of M-current. Annu. Rev. Physiol. 59, 483–504 (1997).
  Article CAS Google Scholar
• Aiken, S.P., Lampe, B.J., Murphy, P.A. & Brown, B.S. Reduction of spike frequency adaptation and blockade of M-current in rat CA1 pyramidal neurones by linopirdine (DuP 996), a neurotransmitter release enhancer. Br. J. Pharmacol. 115, 1163–1168 (1995).
  Article CAS Google Scholar
• Lamas, J.A., Selyanko, A.A. & Brown, D.A. Effects of a cognition-enhancer, linopirdine (DuP 996), on M-type potassium currents (IK(M)) and some other voltage- and ligand-gated membrane currents in rat sympathetic neurons. Eur. J. Neurosci. 9, 605–616 (1997).
  Article CAS Google Scholar
• Rundfeldt, C. & Netzer, R. The novel anticonvulsant retigabine activates M-currents in Chinese hamster ovary cells tranfected with human KCNQ2/3 subunits. Neurosci. Lett. 282, 73–76 (2000).
  Article CAS Google Scholar
• Tatulian, L., Delmas, P., Abogadie, F.C. & Brown, D.A. Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anti-convulsant drug retigabine. J. Neurosci. 21, 5535–5545 (2001).
  Article CAS Google Scholar
• Wang, H.S. et al. KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel. Science 282, 1890–1893 (1998).
  Article CAS Google Scholar
• Selyanko, A.A. et al. Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors. J. Physiol. 522, 349–355 (2000).
  Article CAS Google Scholar
• Shapiro, M.S. et al. Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K+ channels that underlie the neuronal M-current. J. Neurosci. 20, 1710–1721 (2000).
  Article CAS Google Scholar
• Jentsch, T.J. Neuronal KCNQ potassium channels: physiology and role in disease. Nat. Rev. Neurosci. 1, 21–30 (2000).
  Article CAS Google Scholar
• Brown, B.S. & Yu, S.P. Modulation and genetic identification of the M-channel. Prog. Biophys. Mol. Biol. 73, 135–166 (2000).
  Article CAS Google Scholar
• Haley, J.E. et al. The alpha subunit of Gq contributes to muscarinic inhibition of the M-type potassium current in sympathetic neurons. J. Neurosci. 18, 4521–4531 (1998).
  Article CAS Google Scholar
• Haley, J.E. et al. Bradykinin, but not muscarinic, inhibition of M-current in rat sympathetic ganglion neurons involves phospholipase C-beta 4. J. Neurosci. 20, RC105 (2000).
  Article CAS Google Scholar
• Selyanko, A.A., Stansfeld, C.E. & Brown, D.A. Closure of potassium M-channels by muscarinic acetylcholine-receptor stimulants requires a diffusible messenger. Proc. R. Soc. Lond. B Biol. Sci. 250, 119–125 (1992).
  Article CAS Google Scholar
• Marrion, N.V. M-current suppression by agonist and phorbol ester in bullfrog sympathetic neurons. Pflugers. Arch. 426, 296–303 (1994).
  Article CAS Google Scholar
• Selyanko, A.A. & Brown, D.A. Intracellular calcium directly inhibits potassium M channels in excised membrane patches from rat sympathetic neurons. Neuron 16, 151–162 (1996).
  Article CAS Google Scholar
• Cruzblanca, H., Koh, D.S. & Hille, B. Bradykinin inhibits M current via phospholipase C and Ca2+ release from IP3-sensitive Ca2+ stores in rat sympathetic neurons. Proc. Natl. Acad. Sci. USA 95, 7151–7156 (1998).
  Article CAS Google Scholar
• Bofill-Cardona, E. et al. Two different signaling mechanisms involved in the excitation of rat sympathetic neurons by uridine nucleotides. Mol. Pharmacol. 57, 1165–1172 (2000).
  CAS PubMed Google Scholar
• Robbins, J., Marsh, S.J. & Brown, D.A. On the mechanism of M-current inhibition by muscarinic m1 receptors in DNA-transfected rodent neuroblastoma × glioma cells. J. Physiol. 469, 153–178 (1993).
  Article CAS Google Scholar
• del Rio, E. et al. Muscarinic M1 receptors activate phosphoinositide turnover and Ca2+ mobilisation in rat sympathetic neurones, but this signalling pathway does not mediate M-current inhibition. J. Physiol. 520, 101–111 (1999).
  Article CAS Google Scholar
• Suh, B.C. & Hille, B. Recovery from muscarinic modulation of M-current channels requires phosphatidylinositol 4,5-bisphosphate synthesis. Neuron 35, 507–520 (2002).
  Article CAS Google Scholar
• Marrion, N.V. Calcineurin regulates M channel modal gating in sympathetic neurons. Neuron 16, 163–173 (1996).
  Article CAS Google Scholar
• Higashida, H. & Brown, D.A. Two polyphosphatidylinositide metabolites control two K+ currents in a neuronal cell. Nature 323, 333–335 (1986).
  Article CAS Google Scholar
• Pawson, T. & Scott, J.D. Signaling through scaffold, anchoring, and adaptor proteins. Science 278, 2075–2080 (1997).
  Article CAS Google Scholar
• Sudol, M. & Hunter, T. NeW wrinkles for an old domain. Cell 103, 1001–1004 (2000).
  Article CAS Google Scholar
• Colledge, M. & Scott, J.D. AKAPs: from structure to function. Trends Cell Biol. 9, 216–221 (1999).
  Article CAS Google Scholar
• Fraser, I.D., Scott, J.D. Modulation of ion channels: a “current” view of AKAPs. Neuron 23, 423–426 (1999).
  Article CAS Google Scholar
• Westphal, R.S. et al. Regulation of NMDA receptors by an associated phosphatase-kinase signaling complex. Science 285, 93–96 (1999).
  Article CAS Google Scholar
• Coghlan, V.M. et al. Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. Science 267, 108–111 (1995).
  Article CAS Google Scholar
• Klauck, T.M. et al. Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein. Science 271, 1589–1592 (1996).
  Article CAS Google Scholar
• Colledge, M. et al. Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex. Neuron 27, 107–119 (2000).
  Article CAS Google Scholar
• Wen, H. & Levitan, I.B. Calmodulin is an auxiliary subunit of KCNQ2/3 potassium channels. J. Neurosci. 22, 7991–8001 (2002).
  Article CAS Google Scholar
• Dorje, F. et al. Antagonist binding profiles of five cloned human muscarinic receptor subtypes. J. Pharmacol. Exp. Ther. 256, 727–733 (1991).
  CAS PubMed Google Scholar
• Dell'Acqua, M.L. et al. Membrane-targeting sequences on AKAP79 bind phosphatidylinositol-4, 5-bisphosphate. EMBO J. 17, 2246–2260 (1998).
  Article CAS Google Scholar
• Faux, M.C. et al. Mechanism of A-kinase-anchoring protein 79 (AKAP79) and protein kinase C interaction. Biochem. J. 343, 443–452 (1999).
  Article CAS Google Scholar
• Toullec, D. et al. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266, 15771–15781 (1991).
  CAS PubMed Google Scholar
• Herbert, J.M., Augereau, J.M., Gleye, J. & Maffrand, J.P. Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 172, 993–999 (1990).
  Article CAS Google Scholar
• Kobayashi, E., Nakano, H., Morimoto, M. & Tamaoki, T. Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun. 159, 548–553 (1989).
  Article CAS Google Scholar
• Sachs, C.W., Safa, A.R., Harrison, S.D. & Fine, R.L. Partial inhibition of multidrug resistance by safingol is independent of modulation of P-glycoprotein substrate activities and correlated with inhibition of protein kinase C. J. Biol. Chem. 270, 26639–26648 (1995).
  Article CAS Google Scholar
• Rosenmund, C. et al. Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons. Nature 368, 853–856 (1994).
  Article CAS Google Scholar
• Tavalin, S.J. et al. Regulation of GluR1 by the A-kinase anchoring protein 79 (AKAP79) signaling complex shares properties with long-term depression. J. Neurosci. 22, 3044–3051 (2002).
  Article CAS Google Scholar
• Johnson, B.D., Scheuer, T. & Catterall, W.A. Voltage-dependent potentiation of L-type Ca2+ channels in skeletal muscle cells requires anchored cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA 91, 11492–11496 (1994).
  Article CAS Google Scholar
• Gao, T. et al. cAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits. Neuron 19, 185–196 (1997).
  Article CAS Google Scholar
• Cooper, E.C. et al. Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy. Proc. Natl. Acad. Sci. USA 97, 4914–4919 (2000).
  Article CAS Google Scholar
• Sik, A. et al. Localization of the A kinase anchoring protein AKAP79 in the human hippocampus. Eur. J. Neurosci. 12, 1155–1164 (2000).
  Article CAS Google Scholar
• Marx, S.O. et al. Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. Science 295, 496–499 (2002).
  Article CAS Google Scholar
• Delmas, P. et al. Signaling microdomains define the specificity of receptor-mediated InsP(3) pathways in neurons. Neuron 34, 209–220 (2002).
  Article CAS Google Scholar
• Delmas, P. et al. On the role of endogenous G-protein beta gamma subunits in N-type Ca2+ current inhibition by neurotransmitters in rat sympathetic neurones. J. Physiol. 506, 319–329 (1998).
  Article CAS Google Scholar
• Takahashi, Y. et al. 12-Lipoxygenase overexpression in rodent NG108-15 cells enhances membrane excitability by inhibiting M-type K+ channels. J. Physiol. 521, 567–574 (1999).
  Article CAS Google Scholar
• Hoshi, N. et al. KCR1, a membrane protein that facilitates functional expression of non-inactivating K+ currents associates with rat EAG voltage-dependent K+ channels. J. Biol. Chem. 273, 23080–23085 (1998).
  Article CAS Google Scholar