fruitless regulates aggression and dominance in Drosophila (original) (raw)

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Acknowledgements

We thank members of the Kravitz and Dickson laboratories for their support and comments on the manuscript. Work by E.V., E.D., and B.J.D. is supported by Boehringer Ingelheim GmbH. Work by E.A.K. and S.P.N. is supported in part by US National Institutes of Health grants GM067645 and GM072411, respectively.

Author information

Authors and Affiliations

  1. Research Institute of Molecular Pathology, Dr. Bohr-Gasse 7, Vienna, A-1030, Austria
    Eleftheria Vrontou, Ebru Demir & Barry J Dickson
  2. Department of Neurobiology, Harvard Medical School, 220 Longwood Avenue, Boston, 02115, Massachusetts, USA
    Steven P Nilsen & Edward A Kravitz

Authors

  1. Eleftheria Vrontou
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  2. Steven P Nilsen
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  3. Ebru Demir
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  4. Edward A Kravitz
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  5. Barry J Dickson
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Contributions

E.V. conducted the experiments together with S.P.N. in the laboratory of E.A.K.; E.D. generated various fly stocks; E.V. and B.J.D. analyzed the data; and B.J.D. wrote the manuscript with contributions from all other authors.

Corresponding author

Correspondence toBarry J Dickson.

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Competing interests

The authors declare no competing financial interests.

Supplementary information

Supplementary Video 1

A fight between two _fru_C males. The fight begins with low-intensity aggression (fencing), and rapidly escalates to mid- and high-intensity components (lunging and boxing, respectively). (MOV 184 kb)

Supplementary Video 2

A fight between two _fru_C females. One female drives the other off the food source, using low-intensity aggression (fencing) and mid-intensity components (head-butts and shoving). (MOV 266 kb)

Supplementary Video 3

A fight between two _fru_F males. The two males jostle over the resource using female-style aggression involving head-butting and shoving. Fencing is also observed. (MOV 268 kb)

Supplementary Video 4

A fight between a _fru_F male and a _fru_C female. Both flies fight using female-style aggression, as exemplified by the shoves and head-butts that accompany fencing. The _fru_F male does not court the _fru_C female. (MOV 750 kb)

Supplementary Video 5

Fights between a _fru_F male and a _fru_M female. The _fru_M female chases the male away, mostly using lunges in (a), as well as fencing in both videos. Towards the end of the scene shown in (b), the female rises to box—an aggressive gesture to which a male fly would normally respond but the _fru_F male does not. In both videos, the male mostly fences and retreats. Neither fly courts. (MOV 658 kb)

Supplementary Video 6

Fights between a _fru_F male and a _fru_M female. The _fru_M female chases the male away, and both flies engage in fencing. Neither fly courts. Towards the end of the scene, the female rises to box—an aggressive gesture to which a male fly would normally respond but the _fru_F male does not. (MOV 132 kb)

Supplementary Methods (PDF 73 kb)

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Vrontou, E., Nilsen, S., Demir, E. et al. fruitless regulates aggression and dominance in Drosophila.Nat Neurosci 9, 1469–1471 (2006). https://doi.org/10.1038/nn1809

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