Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus (original) (raw)

References

  1. Aimone, J.B., Wiles, J. & Gage, F.H. Potential role for adult neurogenesis in the encoding of time in new memories. Nat. Neurosci. 9, 723–727 (2006).
    Article CAS Google Scholar
  2. Cameron, H.A. & McKay, R.D. Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J. Comp. Neurol. 435, 406–417 (2001).
    Article CAS Google Scholar
  3. Doetsch, F. & Hen, R. Young and excitable: the function of new neurons in the adult mammalian brain. Curr. Opin. Neurobiol. 15, 121–128 (2005).
    Article CAS Google Scholar
  4. Ming, G.L. & Song, H. Adult neurogenesis in the mammalian central nervous system. Annu. Rev. Neurosci. 28, 223–250 (2005).
    Article CAS Google Scholar
  5. Song, H. et al. New neurons in the adult mammalian brain: synaptogenesis and functional integration. J. Neurosci. 25, 10366–10368 (2005).
    Article CAS Google Scholar
  6. Overstreet-Wadiche, L.S. & Westbrook, G.L. Functional maturation of adult-generated granule cells. Hippocampus 16, 208–215 (2006).
    Article Google Scholar
  7. Altman, J. & Das, G.D. Post-natal origin of microneurones in the rat brain. Nature 207, 953–956 (1965).
    Article CAS Google Scholar
  8. Hastings, N.B. & Gould, E. Rapid extension of axons into the CA3 region by adult-generated granule cells. J. Comp. Neurol. 413, 146–154 (1999).
    Article CAS Google Scholar
  9. van Praag, H. et al. Functional neurogenesis in the adult hippocampus. Nature 415, 1030–1034 (2002).
    Article CAS Google Scholar
  10. Zhao, C., Teng, E.M., Summers, R.G., Jr., Ming, G.L. & Gage, F.H. Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus. J. Neurosci. 26, 3–11 (2006).
    Article CAS Google Scholar
  11. Esposito, M.S. et al. Neuronal differentiation in the adult hippocampus recapitulates embryonic development. J. Neurosci. 25, 10074–10086 (2005).
    Article CAS Google Scholar
  12. Ge, S. et al. GABA regulates synaptic integration of newly generated neurons in the adult brain. Nature 439, 589–593 (2006).
    Article CAS Google Scholar
  13. Tashiro, A., Sandler, V.M., Toni, N., Zhao, C. & Gage, F.H. NMDA-receptor–mediated, cell-specific integration of new neurons in adult dentate gyrus. Nature 442, 929–933 (2006).
    Article CAS Google Scholar
  14. Shors, T.J. et al. Neurogenesis in the adult is involved in the formation of trace memories. Nature 410, 372–376 (2001).
    Article CAS Google Scholar
  15. Shors, T.J., Townsend, D.A., Zhao, M., Kozorovitskiy, Y. & Gould, E. Neurogenesis may relate to some but not all types of hippocampal-dependent learning. Hippocampus 12, 578–584 (2002).
    Article Google Scholar
  16. Leuner, B., Gould, E. & Shors, T.J. Is there a link between adult neurogenesis and learning? Hippocampus 16, 216–224 (2006).
    Article Google Scholar
  17. Snyder, J.S., Hong, N.S., McDonald, R.J. & Wojtowicz, J.M. A role for adult neurogenesis in spatial long-term memory. Neuroscience 130, 843–852 (2005).
    Article CAS Google Scholar
  18. Dupret, D. et al. Methylazoxymethanol acetate does not fully block cell genesis in the young and aged dentate gyrus. Eur. J. Neurosci. 22, 778–783 (2005).
    Article Google Scholar
  19. Santarelli, L. et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301, 805–809 (2003).
    Article CAS Google Scholar
  20. Nowakowski, R.S., Lewin, S.B. & Miller, M.W. Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population. J. Neurocytol. 18, 311–318 (1989).
    Article CAS Google Scholar
  21. Gage, F.H., Ray, J. & Fisher, L.J. Isolation, characterization and use of stem cells from the CNS. Annu. Rev. Neurosci. 18, 159–192 (1995).
    Article CAS Google Scholar
  22. Guzowski, J.F. et al. Mapping behaviorally relevant neural circuits with immediate-early gene expression. Curr. Opin. Neurobiol. 15, 599–606 (2005).
    Article CAS Google Scholar
  23. Teixeira, C.M., Pomedli, S.R., Maei, H.R., Kee, N. & Frankland, P.W. Involvement of the anterior cingulate cortex in the expression of remote spatial memory. J. Neurosci. 26, 7555–7564 (2006).
    Article Google Scholar
  24. Kim, J.J. & Fanselow, M.S. Modality-specific retrograde amnesia of fear. Science 256, 675–677 (1992).
    Article CAS Google Scholar
  25. Takehara, K., Kawahara, S. & Kirino, Y. Time-dependent reorganization of the brain components underlying memory retention in trace eyeblink conditioning. J. Neurosci. 23, 9897–9905 (2003).
    Article CAS Google Scholar
  26. Clark, R.E., Broadbent, N.J. & Squire, L.R. Hippocampus and remote spatial memory in rats. Hippocampus 15, 260–272 (2005).
    Article Google Scholar
  27. Martin, S.J., de Hoz, L. & Morris, R.G. Retrograde amnesia: neither partial nor complete hippocampal lesions in rats result in preferential sparing of remote spatial memory, even after reminding. Neuropsychologia 43, 609–624 (2005).
    Article Google Scholar
  28. McNaughton, B.L., Barnes, C.A., Meltzer, J. & Sutherland, R.J. Hippocampal granule cells are necessary for normal spatial learning but not for spatially-selective pyramidal cell discharge. Exp. Brain Res. 76, 485–496 (1989).
    Article CAS Google Scholar
  29. Gould, E., Beylin, A., Tanapat, P., Reeves, A. & Shors, T.J. Learning enhances adult neurogenesis in the hippocampal formation. Nat. Neurosci. 2, 260–265 (1999).
    Article CAS Google Scholar
  30. Kempermann, G., Kuhn, H.G. & Gage, F.H. More hippocampal neurons in adult mice living in an enriched environment. Nature 386, 493–495 (1997).
    Article CAS Google Scholar
  31. van Praag, H., Kempermann, G. & Gage, F.H. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat. Neurosci. 2, 266–270 (1999).
    Article CAS Google Scholar
  32. Kempermann, G., Kuhn, H.G. & Gage, F.H. Experience-induced neurogenesis in the senescent dentate gyrus. J. Neurosci. 18, 3206–3212 (1998).
    Article CAS Google Scholar
  33. Kempermann, G., Gast, D., Kronenberg, G., Yamaguchi, M. & Gage, F.H. Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice. Development 130, 391–399 (2003).
    Article CAS Google Scholar
  34. Schmidt-Hieber, C., Jonas, P. & Bischofberger, J. Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus. Nature 429, 184–187 (2004).
    Article CAS Google Scholar
  35. Wang, S., Scott, B.W. & Wojtowicz, J.M. Heterogenous properties of dentate granule neurons in the adult rat. J. Neurobiol. 42, 248–257 (2000).
    Article CAS Google Scholar
  36. Chawla, M.K. et al. Sparse, environmentally selective expression of Arc RNA in the upper blade of the rodent fascia dentata by brief spatial experience. Hippocampus 15, 579–586 (2005).
    Article CAS Google Scholar
  37. Guzowski, J.F. et al. Recent behavioral history modifies coupling between cell activity and Arc gene transcription in hippocampal CA1 neurons. Proc. Natl. Acad. Sci. USA 103, 1077–1082 (2006).
    Article CAS Google Scholar
  38. Zhang, W.P., Guzowski, J.F. & Thomas, S.A. Mapping neuronal activation and the influence of adrenergic signaling during contextual memory retrieval. Learn. Mem. 12, 239–247 (2005).
    Article Google Scholar
  39. Lois, C. & Alvarez-Buylla, A. Long-distance neuronal migration in the adult mammalian brain. Science 264, 1145–1148 (1994).
    Article CAS Google Scholar
  40. Giese, K.P., Fedorov, N.B., Filipkowski, R.K. & Silva, A.J. Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning. Science 279, 870–873 (1998).
    Article CAS Google Scholar
  41. Jung, M.W. & McNaughton, B.L. Spatial selectivity of unit activity in the hippocampal granular layer. Hippocampus 3, 165–182 (1993).
    Article CAS Google Scholar
  42. Bruel-Jungerman, E., Davis, S., Rampon, C. & Laroche, S. Long-term potentiation enhances neurogenesis in the adult dentate gyrus. J. Neurosci. 26, 5888–5893 (2006).
    Article CAS Google Scholar
  43. Jessberger, S. & Kempermann, G. Adult-born hippocampal neurons mature into activity-dependent responsiveness. Eur. J. Neurosci. 18, 2707–2712 (2003).
    Article Google Scholar
  44. Ramirez-Amaya, V., Marrone, D.F., Gage, F.H., Worley, P.F. & Barnes, C.A. Integration of new neurons into functional neural networks. J. Neurosci. 26, 12237–12241 (2006).
    Article CAS Google Scholar
  45. Frankland, P.W. & Bontempi, B. The organization of recent and remote memories. Nat. Rev. Neurosci. 6, 119–130 (2005).
    Article CAS Google Scholar
  46. Overstreet-Wadiche, L.S., Bensen, A.L. & Westbrook, G.L. Delayed development of adult-generated granule cells in dentate gyrus. J. Neurosci. 26, 2326–2334 (2006).
    Article CAS Google Scholar
  47. Becker, S. A computational principle for hippocampal learning and neurogenesis. Hippocampus 15, 722–738 (2005).
    Article Google Scholar
  48. Wiskott, L., Rasch, M.J. & Kempermann, G. A functional hypothesis for adult hippocampal neurogenesis: avoidance of catastrophic interference in the dentate gyrus. Hippocampus 16, 329–343 (2006).
    Article Google Scholar
  49. Magavi, S.S., Mitchell, B.D., Szentirmai, O., Carter, B.S. & Macklis, J.D. Adult-born and preexisting olfactory granule neurons undergo distinct experience-dependent modifications of their olfactory responses in vivo. J. Neurosci. 25, 10729–10739 (2005).
    Article CAS Google Scholar
  50. Coggeshall, R.E. & Lekan, H.A. Methods for determining numbers of cells and synapses: a case for more uniform standards of review. J. Comp. Neurol. 364, 6–15 (1996).
    Article CAS Google Scholar

Download references