A pilot toxicology study of single-walled carbon nanotubes in a small sample of mice (original) (raw)
Bianco, A. et al. Biomedical applications of functionalised carbon nanotubes. Chem. Commun. 571–577 (2005).
Bianco, A., Kostarelos, K. & Prato, M. Applications of carbon nanotubes in drug delivery. Curr. Opin. Chem. Biol.9, 674–679 (2005). ArticleCAS Google Scholar
Klumpp, C. et al. Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics. Biochim. Biophys. Acta1758, 404–412 (2006). ArticleCAS Google Scholar
Wu, W. et al. Targeted delivery of amphotericin B to cells by using functionalized carbon nanotubes. Angew. Chem. Int. Edn44, 6358–6362 (2005). ArticleCAS Google Scholar
Kam, N. W. et al. Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction. Proc. Natl Acad. Sci. USA102, 11600–11605 (2005). ArticleCAS Google Scholar
Kam, N. W., Liu, Z. & Dai, H. Carbon nanotubes as intracellular transporters for proteins and DNA: an investigation of the uptake mechanism and pathway. Angew. Chem. Int. Edn45, 577–581 (2006). ArticleCAS Google Scholar
Pantarotto, D. et al. Translocation of bioactive peptides across cell membranes by carbon nanotubes. Chem. Commun. 16–17 (2004).
Pantarotto, D. et al. Functionalized carbon nanotubes for plasmid DNA gene delivery. Angew. Chem. Int. Edn43, 5242–5246 (2004). ArticleCAS Google Scholar
Singh, R. et al. Binding and condensation of plasmid DNA onto functionalized carbon nanotubes: toward the construction of nanotube-based gene delivery vectors. J. Am. Chem. Soc.127, 4388–4396 (2005). ArticleCAS Google Scholar
Liu, Y. et al. Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA. Angew. Chem. Int. Edn44, 4782–4785 (2005). ArticleCAS Google Scholar
Kam, N. W., Liu, Z. & Dai, H. Functionalization of carbon nanotubes via cleavable disulfide bonds for efficient intracellular delivery of siRNA and potent gene silencing. J. Am. Chem. Soc.127, 12492–12493 (2005). ArticleCAS Google Scholar
Liu, Z. et al.In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice. Nature Nanotech.2, 47–52 (2007). ArticleCAS Google Scholar
Lison, D. & Muller, J. Lung and systemic responses to carbon nanotubes (CNT) in mice. Toxicol. Sci.101, 179–180 (2008). ArticleCAS Google Scholar
Mitchell, L. A. et al. Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubes. Toxicol. Sci.100, 203–214 (2007). ArticleCAS Google Scholar
Monteiro-Riviere, N. A. et al. Multi-walled carbon nanotube interactions with human epidermal keratinocytes. Toxicol. Lett.155, 377–384 (2005). ArticleCAS Google Scholar
Shvedova, A. A. et al. Exposure to carbon nanotube material: assessment of nanotube cytotoxicity using human keratinocyte cells. J. Toxicol. Environ. Health A66, 1909–1926 (2003). ArticleCAS Google Scholar
Cui, D. et al. Effect of single wall carbon nanotubes on human HEK293 cells. Toxicol. Lett.155, 73–85 (2005). ArticleCAS Google Scholar
Bottini, M. et al. Multi-walled carbon nanotubes induce T lymphocyte apoptosis. Toxicol. Lett.160, 121–126 (2006). ArticleCAS Google Scholar
Kagan, V. E. et al. Direct and indirect effects of single walled carbon nanotubes on RAW 264.7 macrophages: Role of iron. Toxicol. Lett.165, 88–100 (2006). ArticleCAS Google Scholar
Tian, F. et al. Cytotoxicity of single-wall carbon nanotubes on human fibroblasts. Toxicol. In Vitro20(7) 1202–1212 2006. ArticleCAS Google Scholar
Sayes, C. M. et al. Functionalization density dependence of single-walled carbon nanotubes cytotoxicity in vitro.Toxicol. Lett.161, 135–142 (2006). ArticleCAS Google Scholar
Magrez, A. et al. Cellular toxicity of carbon-based nanomaterials. Nano Lett.6, 1121–1125 (2006). ArticleCAS Google Scholar
Shvedova, A. A. et al. Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. Am. J. Physiol. Lung Cell Mol. Physiol.289, L698–L708 (2005). ArticleCAS Google Scholar
Lam, C. W. et al. Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicol. Sci.77, 126–134 (2004). ArticleCAS Google Scholar
Warheit, D. B. et al. Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats. Toxicol. Sci.77, 117–125 (2004). ArticleCAS Google Scholar
Radomski, A. et al. Nanoparticle-induced platelet aggregation and vascular thrombosis. Br. J. Pharmacol.146, 882–893 (2005). ArticleCAS Google Scholar
Wang, H. et al. Biodistribution of carbon single-wall carbon nanotubes in mice. J. Nanosci. Nanotechnol.4, 1019–1024 (2004). ArticleCAS Google Scholar
Singh, R. et al. Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers. Proc. Natl Acad. Sci. USA103, 3357–3362 (2006). ArticleCAS Google Scholar
Cherukuri, P. et al. Near-infrared fluorescence microscopy of single-walled carbon nanotubes in phagocytic cells. J. Am. Chem. Soc.126, 15638–15639 (2004). ArticleCAS Google Scholar
Urch, B. et al. Acute blood pressure responses in healthy adults during controlled air pollution exposures. Environ. Health Perspect.113, 1052–1055 (2005). Article Google Scholar