Sensitive capture of circulating tumour cells by functionalized graphene oxide nanosheets (original) (raw)

• Cristofanilli, M. et al. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. New Engl. J Med. 351, 781–791 (2004).
  Article CAS Google Scholar
• Nagrath, S. et al. Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 450, 1235–1239 (2007).
  Article CAS Google Scholar
• Maheswaran, S. et al. Detection of mutations in EGFR in circulating lung-cancer cells. N. Engl. J. Med. 359, 366–377 (2008).
  Article CAS Google Scholar
• Willipinski-Stapelfeldt, B. et al. Changes in cytoskeletal protein composition indicative of an epithelial–mesenchymal transition in human micrometastatic and primary breast carcinoma cells. Clin. Cancer Res. 11, 8006–8014 (2005).
  Article CAS Google Scholar
• Bednarz-Knoll, N., Alix-Panabières, C. & Pantel, K. Plasticity of disseminating cancer cells in patients with epithelial malignancies. Cancer Metastasis Rev. 31, 673–687 (2012).
  Article CAS Google Scholar
• Pantel, K., Brakenhoff, R. H. & Brandt, B. Detection, clinical relevance and specific biological properties of disseminating tumour cells. Nature Rev. Cancer 8, 329–340 (2008).
  Article CAS Google Scholar
• Lin, H. K. et al. Portable filter-based microdevice for detection and characterization of circulating tumor cells. Clin. Cancer Res. 16, 5011–5018 (2010).
  Article CAS Google Scholar
• Dobrovolskaia, M. A. & McNeil, S. E. Immunological properties of engineered nanomaterials. Nature Nanotech. 2, 469–478 (2007).
  Article CAS Google Scholar
• Xia, X-R., Monteiro-Riviere, N. A. & Riviere, J. E. An index for characterization of nanomaterials in biological systems. Nature Nanotech. 5, 671–675 (2010).
  Article CAS Google Scholar
• Wang, S. et al. Three-dimensional nanostructured substrates toward efficient capture of circulating tumor cells. Angew. Chem. Int. Ed. 121, 9132–9135 (2009).
  Article Google Scholar
• Lee, S-K. et al. Nanowire substrate-based laser scanning cytometry for quantitation of circulating tumor cells. Nano Lett. 12, 2697–2704 (2012).
  Article CAS Google Scholar
• Zhang, N. et al. Electrospun TiO2 nanofiber-based cell capture assay for detecting circulating tumor cells from colorectal and gastric cancer patients. Adv. Mater. 24, 2756–2760 (2012).
  Article CAS Google Scholar
• Liu, Z., Robinson, J. T., Sun, X. & Dai, H. PEGylated nanographene oxide for delivery of water-insoluble cancer drugs. J. Am. Chem. Soc. 130, 10876–10877 (2008).
  Article CAS Google Scholar
• Mohanty, N. & Berry, V. Graphene-based single-bacterium resolution biodevice and DNA transistor: interfacing graphene derivatives with nanoscale and microscale biocomponents. Nano Lett. 8, 4469–4476 (2008).
  Article CAS Google Scholar
• Ramanathan, T. et al. Functionalized graphene sheets for polymer nanocomposites. Nature Nanotech. 3, 327–331 (2008).
  Article CAS Google Scholar
• Dreyer, D. R., Park, S., Bielawski, C. W. & Ruoff, R. S. The chemistry of graphene oxide. Chem. Soc. Rev. 39, 228–240 (2010).
  Article CAS Google Scholar
• Sun, X. et al. Nano-graphene oxide for cellular imaging and drug delivery. Nano Res. 1, 203–212 (2008).
  Article CAS Google Scholar
• Eda, G., Fanchini, G. & Chhowalla, M. Large-area ultrathin films of reduced graphene oxide as a transparent and flexible electronic material. Nature Nanotech. 3, 270–274 (2008).
  Article CAS Google Scholar
• Li, X. et al. Highly conducting graphene sheets and Langmuir–Blodgett films. Nature Nanotech. 3, 538–542 (2008).
  Article CAS Google Scholar
• Wang, H., Wang, X., Li, X. & Dai, H. Chemical self-assembly of graphene sheets. Nano Res. 2, 336–342 (2009).
  Article CAS Google Scholar
• Sieuwerts, A. M. et al. Anti-epithelial cell adhesion molecule antibodies and the detection of circulating normal-like breast tumor cells. J. Natl Cancer Inst. 101, 61–66 (2009).
  Article CAS Google Scholar
• Salic, A. & Mitchison, T. J. A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proc. Natl Acad. Sci. USA 105, 2415–2420 (2008).
  Article CAS Google Scholar
• Lustberg, M., Jatana, K. R., Zborowski, M. & Chalmers, J. J. Emerging technologies for CTC detection based on depletion of normal cells. Recent Results Cancer Res. 195, 97–110 (2012).
  Article Google Scholar
• Stott, S. L. et al. Isolation of circulating tumor cells using a microvortex-generating herringbone-chip. Proc. Natl Acad. Sci. USA 107, 18392–18397 (2010).
  Article CAS Google Scholar
• Mego, M. et al. Characterization of metastatic breast cancer patients with nondetectable circulating tumor cells. Int. J. Cancer 129, 417–423 (2011).
  Article CAS Google Scholar
• Alix-Panabières, C., Schwarzenbach, H. & Pantel, K. Circulating tumor cells and circulating tumor DNA. Annu. Rev. Med. 63, 199–215 (2012).
  Article Google Scholar
• Ozkumur, E. et al. Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells. Sci. Transl. Med. 5, 179ra147 (2013).
  Article Google Scholar
• Krebs, M. G. et al. Analysis of circulating tumor cells in patients with non-small cell lung cancer using epithelial marker-dependent and -independent approaches. J. Thorac. Oncol. 7, 306–315 (2012).
  Article Google Scholar
• Edgerton, S. M., Moore, D. II, Merkel, D. & Thor, A. D. erbB-2 (HER-2) and breast cancer progression. Appl. Immunohistochem. Mol. Morphol. 11, 214–221 (2003).
  Article CAS Google Scholar
• Amir, E. et al. Tissue confirmation of disease recurrence in breast cancer patients: pooled analysis of multi-centre, multi-disciplinary prospective studies. Cancer Treat. Rev. 38, 708–714 (2012).
  Article Google Scholar
• Fehm, T. et al. HER2 status of circulating tumor cells in patients with metastatic breast cancer: a prospective, multicenter trial. Breast Cancer Res. Treat. 124, 403–412 (2010).
  Article CAS Google Scholar
• Riethdorf, S. et al. Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trial. Clin. Cancer Res. 16, 2634–2645 (2010).
  Article CAS Google Scholar
• Pestrin, M. et al. Final results of a multicenter phase II clinical trial evaluating the activity of single-agent Lapatinib in patients with HER2-negative metastatic breast cancer and HER2-positive circulating tumor cells. A proof-of-concept study. Breast Cancer Res. Treat. 134, 283–289 (2012).
  Article CAS Google Scholar