Regulation of transcription by the MLL2 complex and MLL complex–associated AKAP95 (original) (raw)

• Kouzarides, T. Chromatin modifications and their function. Cell 128, 693–705 (2007).
  Article CAS PubMed Google Scholar
• Li, B., Carey, M. & Workman, J.L. The role of chromatin during transcription. Cell 128, 707–719 (2007).
  CAS PubMed Google Scholar
• Shahbazian, M.D. & Grunstein, M. Functions of site-specific histone acetylation and deacetylation. Annu. Rev. Biochem. 76, 75–100 (2007).
  Article CAS PubMed Google Scholar
• Shilatifard, A. Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation. Curr. Opin. Cell Biol. 20, 341–348 (2008).
  Article CAS PubMed PubMed Central Google Scholar
• Ruthenburg, A.J., Allis, C.D. & Wysocka, J. Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark. Mol. Cell 25, 15–30 (2007).
  Article CAS PubMed Google Scholar
• Shilatifard, A. The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis. Annu. Rev. Biochem. 81, 65–95 (2012).
  Article CAS PubMed PubMed Central Google Scholar
• Santos-Rosa, H. et al. Active genes are tri-methylated at K4 of histone H3. Nature 419, 407–411 (2002).
  Article CAS PubMed Google Scholar
• Schneider, R. et al. Histone H3 lysine 4 methylation patterns in higher eukaryotic genes. Nat. Cell Biol. 6, 73–77 (2004).
  Article CAS PubMed Google Scholar
• Bernstein, B.E. et al. Methylation of histone H3 Lys 4 in coding regions of active genes. Proc. Natl. Acad. Sci. USA 99, 8695–8700 (2002).
  Article CAS PubMed PubMed Central Google Scholar
• Barski, A. et al. High-resolution profiling of histone methylations in the human genome. Cell 129, 823–837 (2007).
  Article CAS PubMed Google Scholar
• Dou, Y. et al. Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nat. Struct. Mol. Biol. 13, 713–719 (2006).
  Article CAS PubMed Google Scholar
• Dou, Y. et al. Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell 121, 873–885 (2005).
  Article CAS PubMed Google Scholar
• Hughes, C.M. et al. Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. Mol. Cell 13, 587–597 (2004).
  Article CAS PubMed Google Scholar
• Milne, T.A. et al. MLL targets SET domain methyltransferase activity to Hox gene promoters. Mol. Cell 10, 1107–1117 (2002).
  Article CAS PubMed Google Scholar
• Wysocka, J. et al. WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell 121, 859–872 (2005).
  Article CAS PubMed Google Scholar
• Demers, C. et al. Activator-mediated recruitment of the MLL2 methyltransferase complex to the β-globin locus. Mol. Cell 27, 573–584 (2007).
  Article CAS PubMed PubMed Central Google Scholar
• Vermeulen, M. et al. Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers. Cell 142, 967–980 (2010).
  Article CAS PubMed Google Scholar
• Vermeulen, M. & Timmers, H.T. Grasping trimethylation of histone H3 at lysine 4. Epigenomics 2, 395–406 (2010).
  Article CAS PubMed Google Scholar
• Lim, D.A. et al. Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells. Nature 458, 529–533 (2009).
  Article CAS PubMed PubMed Central Google Scholar
• Rathert, P., Dhayalan, A., Ma, H. & Jeltsch, A. Specificity of protein lysine methyltransferases and methods for detection of lysine methylation of non-histone proteins. Mol. Biosyst. 4, 1186–1190 (2008).
  Article CAS PubMed Google Scholar
• Zhang, K. et al. The Set1 methyltransferase opposes Ipl1 aurora kinase functions in chromosome segregation. Cell 122, 723–734 (2005).
  Article CAS PubMed PubMed Central Google Scholar
• Cho, Y.W. et al. PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex. J. Biol. Chem. 282, 20395–20406 (2007).
  Article CAS PubMed Google Scholar
• Jiang, H. et al. Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains. Cell 144, 513–525 (2011).
  Article CAS PubMed PubMed Central Google Scholar
• Wong, W. & Scott, J.D. AKAP signalling complexes: focal points in space and time. Nat. Rev. Mol. Cell Biol. 5, 959–970 (2004).
  Article CAS PubMed Google Scholar
• Jungmann, R.A. & Kiryukhina, O. Cyclic AMP and AKAP-mediated targeting of protein kinase A regulates lactate dehydrogenase subunit A mRNA stability. J. Biol. Chem. 280, 25170–25177 (2005).
  Article CAS PubMed Google Scholar
• Eide, T. et al. Protein kinase A-anchoring protein AKAP95 interacts with MCM2, a regulator of DNA replication. J. Biol. Chem. 278, 26750–26756 (2003).
  Article CAS PubMed Google Scholar
• Li, Y. et al. A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. Genes Dev. 20, 2566–2579 (2006).
  Article CAS PubMed PubMed Central Google Scholar
• Collas, P., Le Guellec, K. & Tasken, K. The A-kinase-anchoring protein AKAP95 is a multivalent protein with a key role in chromatin condensation at mitosis. J. Cell Biol. 147, 1167–1180 (1999).
  Article CAS PubMed PubMed Central Google Scholar
• Bomar, J., Moreira, P., Balise, J.J. & Collas, P. Differential regulation of maternal and paternal chromosome condensation in mitotic zygotes. J. Cell Sci. 115, 2931–2940 (2002).
  CAS PubMed Google Scholar
• Akileswaran, L., Taraska, J.W., Sayer, J.A., Gettemy, J.M. & Coghlan, V.M. A-kinase-anchoring protein AKAP95 is targeted to the nuclear matrix and associates with p68 RNA helicase. J. Biol. Chem. 276, 17448–17454 (2001).
  Article CAS PubMed Google Scholar
• van den Berg, D.L. et al. An Oct4-centered protein interaction network in embryonic stem cells. Cell Stem Cell 6, 369–381 (2010).
  Article CAS PubMed PubMed Central Google Scholar
• An, W. & Roeder, R.G. Reconstitution and transcriptional analysis of chromatin in vitro. Methods Enzymol. 377, 460–474 (2004).
  Article CAS PubMed Google Scholar
• An, W., Kim, J. & Roeder, R.G. Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53. Cell 117, 735–748 (2004).
  Article CAS PubMed Google Scholar
• An, W., Palhan, V.B., Karymov, M.A., Leuba, S.H. & Roeder, R.G. Selective requirements for histone H3 and H4 N termini in p300-dependent transcriptional activation from chromatin. Mol. Cell 9, 811–821 (2002).
  Article CAS PubMed Google Scholar
• Tsukiyama, T. & Wu, C. Purification and properties of an ATP-dependent nucleosome remodeling factor. Cell 83, 1011–1020 (1995).
  Article CAS PubMed Google Scholar
• Carr, D.W., Hausken, Z.E., Fraser, I.D., Stofko-Hahn, R.E. & Scott, J.D. Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein: cloning and characterization of the RII-binding domain. J. Biol. Chem. 267, 13376–13382 (1992).
  CAS PubMed Google Scholar
• Eide, T. et al. Distinct but overlapping domains of AKAP95 are implicated in chromosome condensation and condensin targeting. EMBO Rep. 3, 426–432 (2002).
  Article CAS PubMed PubMed Central Google Scholar
• Goo, Y.H. et al. Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins. Mol. Cell Biol. 23, 140–149 (2003).
  Article CAS PubMed PubMed Central Google Scholar
• Pavri, R. et al. Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. Cell 125, 703–717 (2006).
  Article CAS PubMed Google Scholar
• Lin, J.J. et al. Mediator coordinates PIC assembly with recruitment of CHD1. Genes Dev. 25, 2198–2209 (2011).
  Article CAS PubMed PubMed Central Google Scholar
• Lauberth, S.M. et al. H3K4me3 interactions with TAF3 regulate preinitiation complex assembly and selective gene activation. Cell 152, 1021–1036 (2013).
  Article CAS PubMed PubMed Central Google Scholar
• Tang, Z. et al. SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53. Cell 154, 297–310 (2013).
  Article CAS PubMed PubMed Central Google Scholar
• Beene, D.L. & Scott, J.D. A-kinase anchoring proteins take shape. Curr. Opin. Cell Biol. 19, 192–198 (2007).
  Article CAS PubMed PubMed Central Google Scholar
• Dignam, J.D., Lebovitz, R.M. & Roeder, R.G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11, 1475–1489 (1983).
  Article CAS PubMed PubMed Central Google Scholar
• Guermah, M., Kim, J. & Roeder, R.G. Transcription of in vitro assembled chromatin templates in a highly purified RNA polymerase II system. Methods 48, 353–360 (2009).
  Article CAS PubMed PubMed Central Google Scholar
• Nelson, J.D., Denisenko, O. & Bomsztyk, K. Protocol for the fast chromatin immunoprecipitation (ChIP) method. Nat. Protoc. 1, 179–185 (2006).
  Article CAS PubMed Google Scholar
• Livak, K.J. & Schmittgen, T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔ_C_T method. Methods 25, 402–408 (2001).
  Article CAS PubMed Google Scholar
• Zhang, J., Kalkum, M., Chait, B.T. & Roeder, R.G. The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2. Mol. Cell 9, 611–623 (2002).
  Article CAS PubMed Google Scholar