The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms (original) (raw)

This is a preview of subscription content, access via your institution

Accession codes

Accessions

Protein Data Bank

References

  1. Blandin, S. et al. Cell 116, 661–670 (2004).
    Article CAS Google Scholar
  2. Sinden, R.E. Int. J. Parasitol. 34, 1441–1450 (2004).
    Article CAS Google Scholar
  3. Tomas, A.M. et al. EMBO J. 20, 3975–3983 (2001).
    Article CAS Google Scholar
  4. Malkin, E.M. et al. Vaccine 23, 3131–3138 (2005).
    Article CAS Google Scholar
  5. Hisaeda, H. et al. Infect. Immun. 68, 6618–6623 (2000).
    Article CAS Google Scholar
  6. Holm, L. & Sander, C. Science 273, 595–603 (1996).
    Article CAS Google Scholar
  7. Zollner, G.E., Ponsa, N., Coleman, R.E., Sattabongkot, J. & Vaughan, J.A. J. Parasitol. 91, 453–457 (2005).
    Article Google Scholar
  8. Lawrence, M.C. & Colman, P.M. J. Mol. Biol. 234, 946–950 (1993).
    Article CAS Google Scholar
  9. Spano, F., Matsuoka, H., Ozawa, R., Chinzei, Y. & Sinden, R.E. Parassitologia 38, 559–563 (1996).
    CAS PubMed Google Scholar
  10. Ranawaka, G.R., Fleck, S.L., Alejo-Blanco, A.R. & Sinden, R.E. Parasitology 109, 403–411 (1994).
    Article Google Scholar
  11. Stura, E.A. et al. Acta Crystallogr. D Biol. Crystallogr. 50, 556–562 (1994).
    Article CAS Google Scholar
  12. van Amerongen, A., Sauerwein, R.W., Beckers, P.J., Meloen, R.H. & Meuwissen, J.H. Parasite Immunol. 11, 425–428 (1989).
    Article CAS Google Scholar

Download references

Acknowledgements

We thank the Malaria Vaccine Development Branch of the NIAID for Pvs25 and Y.T. Bryceson of NIAID for cDNA synthesis. X-ray data were collected at the SER-CAT 22-ID and SBC-CAT 19-ID beamlines at the Advanced Photon Source, which are supported by the US Department of Energy, Office of Science, Office of Basic Energy Sciences under contract W-31-109-Eng-38. This research was supported by the intramural research programs of the NIH and NIAID.

Author information

Author notes

  1. Ajay K Saxena
    Present address: School of Life Sciences, Jawaharlal Nehru University, Room-403, New Mehrauli Road, New Delhi, 110067, India
  2. Anthony W Stowers
    Present address: CSL Limited ACN 051 588 348, 45 Poplar Road, Parkville, Victoria, 3052, Australia

Authors and Affiliations

  1. Structural Biology Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases (NIAID), US National Institutes of Health (NIH), Twinbrook 2, 12441 Parklawn Drive, Rockville, 20852, Maryland, USA
    Ajay K Saxena, Kavita Singh, Hua-Poo Su, Michael M Klein & David N Garboczi
  2. Malaria Vaccine Development Branch, NIAID, NIH, Twinbrook 1, 5640 Fishers Lane, Rockville, 20852, Maryland, USA
    Anthony W Stowers, Allan J Saul & Carole A Long

Authors

  1. Ajay K Saxena
  2. Kavita Singh
  3. Hua-Poo Su
  4. Michael M Klein
  5. Anthony W Stowers
  6. Allan J Saul
  7. Carole A Long
  8. David N Garboczi

Corresponding authors

Correspondence toAjay K Saxena or David N Garboczi.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Supplementary information

Rights and permissions

About this article

Cite this article

Saxena, A., Singh, K., Su, HP. et al. The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms.Nat Struct Mol Biol 13, 90–91 (2006). https://doi.org/10.1038/nsmb1024

Download citation