Wood, R.D. Nucleotide excision repair in mammalian cells. J. Biol. Chem.272, 23465–23468 (1997). ArticleCAS Google Scholar
De Laat, W.L., Jaspers, N.G. & Hoeijmakers, J.H. Molecular mechanism of nucleotide excision repair. Genes Dev.13, 768–785 (1999). ArticleCAS Google Scholar
Mitchell, D.L. The induction and repair of lesions produced by the photolysis of (6–4) photoproducts in normal and UV-hypersensitive human cells. Mutat. Res.194, 227–237 (1988). CASPubMed Google Scholar
Reardon, J.T. & Sancar, A. Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease. Genes Dev.17, 2539–2551 (2003). ArticleCAS Google Scholar
Friedberg, E.C., Walker, G.C. & Siede, W. DNA Repair and Mutagenesis (ASM Press, Washington, DC, USA, 1995). Google Scholar
Kraemer, K.H., Lee, M.M. & Scotto, J. DNA repair protects against cutaneous and internal neoplasia: evidence from xeroderma pigmentosum. Carcinogenesis5, 511–514 (1984). ArticleCAS Google Scholar
States, J.C., McDuffie, E.R., Myrand, S.P., McDowell, M. & Cleaver, J.E. Distribution of mutations in the human xeroderma pigementosum group A gene and their relationships to the functional regions of the DNA damage recognition protein. Hum. Mutat.12, 103–113 (1998). ArticleCAS Google Scholar
Cleaver, J.E., Thompson, L.H., Richardson, A.S. & States, J.C. A summary of mutations in the UV-sensitive disorders: xeroderma pigementosum, Cockayne syndrome, and trichothiodystrophy. Hum. Mutat.14, 9–22 (1999). ArticleCAS Google Scholar
Huang, J.C., Svoboda, D., Reardon, J.T. & Sancar, A. Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5′ and the 6th phosphodiester bond 3′ to the photodimer. Proc. Natl. Acad. Sci. USA89, 3664–3668 (1992). ArticleCAS Google Scholar
Evans, E., Fellows, J., Coffer, A. & Wood, R.D. Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein. EMBO J.16, 625–638 (1997). ArticleCAS Google Scholar
Aboussekhra, A. et al. Mammalian DNA nucleotide excision repair reconstituted with purified protein components. Cell80, 859–868 (1995). ArticleCAS Google Scholar
Mellon, I., Spivak, G. & Hanawalt, P.C. Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene. Cell51, 241–249 (1987). ArticleCAS Google Scholar
Friedberg, E.C. DNA damage and repair. Nature421, 436–440 (2003). Article Google Scholar
Mu, D. et al. Reconstitution of human DNA repair excision nuclease in a highly defined system. J. Biol. Chem.270, 2415–2418 (1995). ArticleCAS Google Scholar
Sugasawa, K. et al. Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair. Mol. Cell2, 223–232 (1998). ArticleCAS Google Scholar
Araújo, S.J. et al. Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK. Genes Dev.14, 349–359 (2000). PubMedPubMed Central Google Scholar
Volker, M. et al. Sequential assembly of the nucleotide excision repair factors in vivo. Mol. Cell8, 213–224 (2001). ArticleCAS Google Scholar
Yang, Z.G., Liu, Y., Mao, L.Y., Zhang, J.-T. & Zou, Y. Dimerization of human XPA and formation of XPA2-RPA protein complex. Biochemistry41, 13012–13020 (2002). ArticleCAS Google Scholar
He, Z., Henricksen, L.A., Wold, M.S. & Ingles, C.J. RPA involvement in the damage-recognition and incision steps of nucleotide excision repair. Nature374, 566–569 (1995). ArticleCAS Google Scholar
Li, L., Lu, X., Peterson, C.A. & Legerski, R.J. An interaction between the DNA repair factor XPA and replication protein A appears essential for nucleotide excision repair. Mol. Cell. Biol.15, 5396–5402 (1995). ArticleCAS Google Scholar
Park, C.H., Mu, D., Reardon, J.T. & Sancar, A. The general transcription-repair factor TFIIH is recruited to the excision repair complex by the XPA protein independent of the TFIIE transcription factor. J. Biol. Chem.270, 4896–4902 (1995). ArticleCAS Google Scholar
Kuraoka, I. et al. Identification of a damaged-DNA binding domain of the XPA protein. Mutat. Res.362, 87–95 (1996). Article Google Scholar
Cleaver, J.E. & States, J.C. The DNA damage-recognition problem in human and other eukaryotic cells: the XPA damage binding protein. Biochem. J.328, 1–12 (1997). ArticleCAS Google Scholar
Ikegami, T. et al. Solution structure of the DNA-and RPA-binding domain of the human repair factor XPA. Nat. Struct. Biol.5, 701–706 (1998). ArticleCAS Google Scholar
Buchko, G.W. et al. DNA-XPA interactions: a 31P NMR and molecular modeling study of dCCAATAACC association with the minimal DNA-binding domain (M98–F219) of the nucleotide excision repair protein XPA. Nucleic Acids Res.29, 2635–2643 (2001). ArticleCAS Google Scholar
Carreau, M. et al. Development of a new easy complementation assay for DNA repair deficient human syndromes using cloned repair genes. Carcinogenesis16, 1003–1009 (1995). ArticleCAS Google Scholar
Mellon, I., Hock, T., Reid, R., Porter, P.C. & States, J.C. Polymorphisms in the human xeroderma pigmentosum group A gene and their impact on cell survival and nucleotide excision repair. DNA Repair (Amst.)1, 531–546 (2002). ArticleCAS Google Scholar
Jones, C.J. & Wood, R.D. Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA. Biochemistry32, 12096–12104 (1993). ArticleCAS Google Scholar
You, J.S., Wang, M. & Lee, S.H. Biochemical analysis of the damage recognition process in nucleotide excision repair. J. Biol. Chem.278, 7476–7485 (2003). ArticleCAS Google Scholar
Werner, M.H., Gronenborn, A.M. & Clore, G.M. Intercalation, DNA kinking, and the control of transcription. Science271, 778–784 (1996). ArticleCAS Google Scholar
Rost, B., Yachdav, G. & Liu, J. The PredictProtein server. Nucleic Acids Res.32, W321–W326 (2004). ArticleCAS Google Scholar
Riedl, T., Hanaoka, F. & Egly, J.M. The comings and goings of nucleotide excision repair factors on damaged DNA. EMBO J.22, 5293–5303 (2003). ArticleCAS Google Scholar
Enzlin, J.H. & Schärer, O.D. The active site of the DNA repair endonuclease XPF-ERCC1 forms a highly conserved nuclease motif. EMBO J.21, 2045–2053 (2002). ArticleCAS Google Scholar
McDowell, M.L., Nguyen, T. & Cleaver, J.E. A single-site mutation in the XPAC gene alters photoproduct recognition. Mutagenesis8, 155–161 (1993). ArticleCAS Google Scholar
Kobayashi, T. et al. Mutational analysis of a function of xeroderma pigmentosum group A (XPA) protein in strand specific repair. Nucleic Acids Res.26, 4662–4668 (1998). ArticleCAS Google Scholar
Fujiwara, Y. et al. Characterization of DNA recognition by the human UV-damaged DNA-binding protein. J. Biol. Chem.274, 20027–20033 (1999). ArticleCAS Google Scholar
Janicijevic, A. et al. DNA bending by the human damage recognition complex XPC-HR23B. DNA Repair (Amst.)2, 325–336 (2003). ArticleCAS Google Scholar
Mu, D., Wakasugi, M., Hsu, D.S. & Sancar, A. Characterization of reaction intermediates of human excision repair nuclease. J. Biol. Chem.272, 28971–28979 (1997). ArticleCAS Google Scholar
O'Donovan, A., Davies, A.A., Moggs, J.G., West, S.C. & Wood, R. XPG endonuclease makes the 3′ incision in human DNA nucleotide excision repair. Nature371, 432–435 (1994). ArticleCAS Google Scholar
Ortiz-Lombardia, M. et al. Crystal structure of a DNA Holliday junction. Nat. Struct. Biol.6, 913–917 (1999). ArticleCAS Google Scholar
Isaacs, R.J. & Spielmann, H.P. A model for initial DNA lesion recognition by NER and MMR based on local conformational flexibility. DNA Repair (Amst.)3, 455–464 (2004). ArticleCAS Google Scholar
Weir, H.M. et al. Structure of the HMG box motif in the B-domain of HMG1. EMBO J.12, 1311–1319 (1993). ArticleCAS Google Scholar
Read, C.M., Cary, P.D., Crane-Robinson, C., Driscoll, P.C. & Norman, D.G. Solution structure of a DNA-binding domain from HMG1. Nucleic Acids Res.21, 3427–3436 (1993). ArticleCAS Google Scholar
Kasparkova, J., Mellish, K.J., Qu, Y. & Brabec, V. Site-specific d(GpG) intrastrand cross-links formed by dinuclear platinum complexes. Bending and NMR studies. Biochemistry35, 16705–16713 (1996). ArticleCAS Google Scholar
Missura, M. et al. Double-check probing of DNA binding and unwinding by XPA-RPA: an architectural function in DNA repair. EMBO J.20, 3554–3564 (2001). ArticleCAS Google Scholar
Dip, R. & Naegeli, H. Binding of the DNA-dependent protein kinase catalytic subunit to Holliday junctions. Biochem. J.381, 165–174 (2004). ArticleCAS Google Scholar
Ford, J.M. & Hanawalt, P.C. Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance. Proc. Natl. Acad. Sci. USA92, 8876–8880 (1995). ArticleCAS Google Scholar