Paradoxical regulation of Bcl-2 family proteins by 17β-oestradiol in human breast cancer cells MCF-7 (original) (raw)

References

• Ashkenazi, A & Dixit, VM (1998). Death receptors: signaling and modulation. Science 281: 1305–1308.
  Article CAS PubMed Google Scholar
• Bardelli, A, Longati, P, Albero, D, Goruppi, S, Schneider, C, Ponzetto, C & Comoglio, PM (1996). HGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell death. EMBO J 15: 6205–6212.
  Article CAS PubMed PubMed Central Google Scholar
• Bursch, W, Ellinger, A, Kienzl, H, Torok, L, Pandey, S, Sirkorska, M, Walker, R & Hermann, RS (1996). Active cell death induced by the anti-estrogens tamoxifen and ICI 164384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy. Carcinogenesis 17: 1595–1607.
  Article CAS PubMed Google Scholar
• Bargou, RC, Daniel, PT, Mapara, MY, Bommert, K, Wagener, C, Kallinich, B, Royer, HD & Dorken, B (1995). Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis. Int J Cancer 16: 854–859.
  Article Google Scholar
• Chittenden, T, Flemington, C, Houghton, AB, Ebb, RG, Gallo, GJ, Elangovan, B, Chinnadurai, G & Lutz, RJ (1995). A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions. EMBO J 14: 5589–5596.
  Article CAS PubMed PubMed Central Google Scholar
• de Cupis, A & Favoni, RE (1997). Oestrogen/growth factor cross-talk in breast carcinoma: a specific target for novel antioestrogens. Trends Pharmacol Sci 18: 245–251.
  Article CAS PubMed Google Scholar
• Farrow, SN, White, JHM, Martinou, I, Raven, T, Pun, K-T, Grinham, CJ, Martinour, J-C & Brown, R (1995). Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K. Nature 374: 731–73.
  Article CAS PubMed Google Scholar
• Fishman, J, Osborne, MP & Telang, NT (1995). The role of estrogen in mammary carcinogenesis. Ann NY Acad Sci 768: 91–100.
  Article CAS PubMed Google Scholar
• Grillot, DA, Gonzalez-Garcia, M, Ekhterae, D, Duan, L, Inohara, N, Ohta, S, Seldin, MF & Nunez, G (1997). Genomic organization, promoter region analysis, and chromosome localization of the mouse bcl-x gene. J Immunol 158: 4750–4757.
  CAS PubMed Google Scholar
• Herrmann, JL, Beham, AW, Sarkiss, M, Chiao, PJ, Rands, MT, Bruckheimer, EM, Brisbay, S & McDonnell, TJ (1997). Bcl-2 suppresses apoptosis resulting from disruption of the NF-kappa B survival pathway. Exp Cell Res 237: 101–109.
  Article CAS PubMed Google Scholar
• Huang, Y, Ray, S, Reed, JC, Ibrado, AM, Tang, C, Nawabi, A & Bhalla, K (1997). Estrogen increases intracellular p26 Bcl-2 to p21 Bax ratios and inhibits taxol-induced apoptosis of human breast cancer MCF-7 cells. Breast Cancer Res Treat 42: 73–81.
  Article CAS PubMed Google Scholar
• Hu, Y, Benedict, MA, Wu, D, Inohara, N & Nunez, G (1998). Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation. Proc Natl Acad Sci USA 95: 4386–4391.
  Article CAS PubMed PubMed Central Google Scholar
• Jordan, VC (1998). Antiestrogenic action of raloxifene and tamoxifen: today and tomorrow. J Natl Cancer Inst 90: 967–971.
  Article CAS PubMed Google Scholar
• Kandouz, M, Siromachkova, M, Jacob, D, Chretien-Marquet, B, Therwath, A & Gompel, A (1996). Antagonism between estradiol and progestin on Bcl-2 expression in breast-cancer cells. Int J Cancer 68: 120–125.
  Article CAS PubMed Google Scholar
• Kluck, RM, Bossy-Wetzel, E, Green, DR & Newmeyer, DD (1997). The release of cytochrome c from mitochondria blocked. Science 275: 1129–1132.
  Article Google Scholar
• Kroemer, G (1997). The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 3: 614–620.
  Article CAS PubMed Google Scholar
• Kyprianou, N, English, HF, Davidson, NE & Isaacs, JT (1991). Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation. Cancer Res 51: 162–166.
  CAS PubMed Google Scholar
• Leung, LK, Do, L & Wang, TTY (1998). Regulation of death promoter Bak expression by cell density and 17β-estradiol in MCF-7 cells. Cancer Lett 124: 47–52.
  Article CAS PubMed Google Scholar
• McDonnell, TJ, Beham, A, Sarkiss, M, Andersen, M & Lo, P (1996). Importance of the Bcl-2 family in cell death regulation. Experientia 52: 1008–1017.
  Article CAS PubMed Google Scholar
• Mikulski, SM (1994). Pathogenesis of cancer in view of mutually opposing apoptotic and anti-apoptotic growth signals (Review). Int J Oncol 4: 1257–1263.
  CAS PubMed Google Scholar
• Nenci, I, Marchetti, E & Queerzoli, P (1988). Commentary on human mammary preneoplasia. The estrogen receptor-promotion hypothesis. J Steroid Biochem 30: 105–106.
  Article CAS PubMed Google Scholar
• Olopade, OI, Adeyanju, MO, Safa, AR, Hagos, F, Mick, R, Thompson, CB & Recant, WM (1997). Over-expression of BCL-x protein in primary breast cancer is associated with high tumor grade and nodal metastases. Cancer J Sci Am 3: 230–237.
  CAS PubMed Google Scholar
• Pecci, A, Scholz, A, Pelster, D & Beato, M (1997). Progestins prevent apoptosis in a rat endometrial cell line and increase the ratio of bcl-XL to bcl-XS. J Biol Chem 272: 11791–11798.
  Article CAS PubMed Google Scholar
• Reed, JC (1994). Bcl-2 and the regulation of programmed cell death. J Cell Biol 124: 1–6.
  Article CAS PubMed Google Scholar
• Saeed, B, Zhang, H & Ng, SC (1997). Apoptotic program is initiated but not completed in LNCap cells in response to growth in charcoal-stripped media. Prostate 31: 145–152.
  Article CAS PubMed Google Scholar
• Sattle, M, Liang, H, Nettesheim, D, Meadows, RP, Harlan, JE, Eberstadt, M, Yoon, HS, Shuker, SB, Chang, BS, Minn, AJ, Thompson, CB & Fesik, SW (1997). Structure of Bcl-x(L)-Bak peptide complex: recognition between regulators of apoptosis. Science 275: 983–986.
  Article Google Scholar
• Srinivasan, A, Li, F, Wong, A, Kodandapani, L, Smidt, R Jr, Krebs, JF, Fritz, LC, Wu, JC & Tomaselli, KJ (1998). Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells. J Biol Chem 273: 4523–4529.
  Article CAS PubMed Google Scholar
• Teixeira, C, Reed, JC & Pratt, MA (1995). Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells. Cancer Res 55: 3902–3907.
  CAS PubMed Google Scholar
• Tsujimoto, Y, Cossman, J, Jaffe, E & Croce, CM (1985). Involvement of the bcl-2 gene in human follicular lymphoma. Science 228: 1440–1443.
  Article CAS PubMed Google Scholar
• Wallach, D, Boldin, M, Varfolomeev, E, Beyaert, R, Vandenabeele, P & Fiers, W (1997). Cell death induction by receptors of the TNF family: towards a molecular understanding. FEBS Lett 410: 96–106.
  Article CAS PubMed Google Scholar
• Wang, TT & Phang, JM (1995). Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7. Cancer Res 55: 2487–2489.
  CAS PubMed Google Scholar
• Wyllie, AH (1997). Apoptosis and carcinogenesis. Eur J Cell Biol 73: 189–197.
  CAS PubMed Google Scholar
• Yang, J, Liu, X, Bhalla, K, Kim, CN, Ibrado, AM, Cai, J, Peng, T-I, Jones, DP & Wang, X (1997). Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275: 1129–1132.
  Article CAS PubMed Google Scholar
• Zha, JP, Harada, H, Yang, E, Jockel, J & Korsmeyer, SJ (1996). Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14–3–3 not BCL-x(L). Cell 87: 619–628.
  Article CAS PubMed Google Scholar
• Zhang, GJ, Kimijima, I, Abe, R, Watanabe, T, Kanno, M, Hara, K & Tsuchiya, A (1998). Apoptotic index correlates to bcl-2 and p53 protein expression, histological grade and prognosis in invasive breast cancers. Anticancer Res 18: 1989–1998.
  CAS PubMed Google Scholar

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