Dental manifestations in severe combined immunodeficiency following bone marrow transplantation (original) (raw)
- Case Report
- Published: 26 April 2000
Bone Marrow Transplantation volume 25, pages 1007–1009 (2000)Cite this article
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Abstract
Severe combined immunodeficiency (SCID) is a rare primary immunodeficiency disorder with an estimated overall frequency of 1 in 75 000 live births. Bone marrow transplantation is the only curative treatment available. Using T cell-depleted HLA non-identical bone marrow requires preconditioning with a short course of cytotoxic chemotherapy. We report severe dental developmental anomalies in three such patients under long-term follow up. Bone Marrow Transplantation (2000) 25, 1007–1009.
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Authors and Affiliations
- Dept of Child Dental Health, Dental Hospital and School, Newcastle upon Tyne, UK
BOI Cole & RR Welbury - Children’s BMT Unit, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK
E Bond & M Abinun
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- BOI Cole
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Cole, B., Welbury, R., Bond, E. et al. Dental manifestations in severe combined immunodeficiency following bone marrow transplantation.Bone Marrow Transplant 25, 1007–1009 (2000). https://doi.org/10.1038/sj.bmt.1702382
- Received: 19 October 1999
- Accepted: 01 February 2000
- Published: 26 April 2000
- Issue Date: 01 May 2000
- DOI: https://doi.org/10.1038/sj.bmt.1702382