- Turk B, Turk D, Turk V . Lysosomal cysteine proteases: more than scavengers. Biochim Biophys Acta. 2000;1477:98–111.
Article CAS Google Scholar
- Koblinski JE, Sloane BF . Is altered localization of cathepsin B casually related to malignant progression? In: N Katunuma, ed. Medical Aspects of Proteinases and Proteinase Inhibitors, Tokyo, Japan: IOS Press; 1997:185–194.
Google Scholar
- Demchik LL, Sameni M, Nelson K, et al. Cathepsin B and glioma invasion. Int J Dev Neurosci. 1999;17:483–494.
Article CAS Google Scholar
- Pilkington GJ . Tumour cell migration in the CNS. Brain Pathol. 1994;4:157–166.
Article CAS Google Scholar
- Gladson CL . The extracellular matrix of gliomas: modulation of cell function. J Neuropathol Exp Neurol. 1999;58:1029–1040.
Article CAS Google Scholar
- Schmitt M, Janicke F, Graeff F . Tumour-associated proteases. Fibrinolysis. 1992;6:3–26.
Article CAS Google Scholar
- Levičar N, Strojnik T, Kos J, et al. Lysosomal enzymes, cathepsins in glioma invasion. J Neuro-Oncol. 2002;58:21–32.
Article Google Scholar
- Strojnik T, Kos J, Židanik B, et al. Cathepsin B immunohistochemical staining in tumour and endothelial cells is a new prognostic factor for survival in patients with brain tumors. Clin Cancer Res. 1999;5:559–567.
CAS PubMed Google Scholar
- Sivaparvathi M, Yamamoto M, Nicolson GL, et al. Expression and immunohistochemical localization of cathepsin L during the progression of human gliomas. Clin Exp Metastasis. 1996;14:27–34.
Article CAS Google Scholar
- Lah TT, Strojnik T, Levičar N, et al. Clinical and experimental studies of cysteine cathepsins and their inhibitors in human brain tumors. Int J Biol Markers. 2000;15:90–93.
Article CAS Google Scholar
- Thompson C . Apoptosis in the pathogenesis and treatment of disease. Science. 1995;267:1456–1462.
Article CAS Google Scholar
- Jaattela M . Escaping cell death: survival proteins in cancer — review. Exp Cell Res. 1999;248:30–43.
Article CAS Google Scholar
- Scaffidi C, Fulda S, Srinivasan A, et al. Two CD95 (APO-1/Fas) signaling pathways. EMBO J. 1998;17:1675–1687.
Article CAS Google Scholar
- Adams JM, Cory S . The Bcl-2 protein family: arbiters of cell survival. Science. 1998;281:1322–1326.
Article CAS Google Scholar
- Kroemer G . The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med. 1997;3:934
Article CAS Google Scholar
- Zhao M, Eaton JW, Brunk UT . Protection against oxidant-mediated lysosomal rupture: a new anti-apoptotic activity of Bcl-2. FEBS Lett. 2000;485:104–108.
Article CAS Google Scholar
- Kidd VJ, Lahti JM, Teitz T . Proteolytic degradation of apoptosis. Semin Cell Dev Biol. 2000;11:191–201.
Article CAS Google Scholar
- Stoka V, Turk B, Schendel SL, et al. Lysosomal protease pathway to apoptosis. J Biol Chem. 2001;276:3149–3157.
Article CAS Google Scholar
- Katunuma N, Matsui A, Le QT, et al. Novel procaspase-3 activating cascade mediated by lysoapoptases and its biological significances in apoptosis. Adv Enzyme Regul. 2001;41:237–250.
Article CAS Google Scholar
- Kin Y, Chintala SK, Go Y, et al. A novel role for urokinase-type plasminogen activator receptor in apoptosis of malignant gliomas. Int J Oncol. 2000;17:61–65.
CAS PubMed Google Scholar
- Castro MG, Rowe J, Morrison E, et al. Calcium-phosphate, DEAE–dextran coprecipitation, and electroporation to transfer genes into neuronal and glial cell lines. In: Lowenstein PR, Enquist LW, eds. Protocols for Gene Transfer in Neuroscience: Towards Gene Therapy of Neurological Disorders. New York: Wiley; 1996:9–23.
Google Scholar
- Werle B, Staib A, Julke B, et al. Fluorimetric microassays for the determination of cathepsin L and cathepsin S activities. Biol Chem. 1999;380:1109–1116.
Article CAS Google Scholar
- Holst-Hansen C, Johannessen B, Hoyer-Hansen G, et al. Urokinase-type plasminogen activation in three human breast cancer cell lines correlates with their in vitro invasiveness. Clin Exp Metastasis. 1996;14:297–307.
CAS PubMed Google Scholar
- Duke RC, Cohen JJ . Morphological and biochemical assays of apoptosis. In: Coligan JE, Kruisbeak AM, eds. Current Protocols in Immunology. New York: Wiley; 1992. 3–17.
Google Scholar
- Nicolleti I, Migliorati G, Pagliacci MC, et al. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods. 1991;139:271–279.
Article Google Scholar
- Thornberry NA, Bull HG, Calaycay JR, et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature. 1992;356:768–774.
Article CAS Google Scholar
- Kirschke H, Eerola R, Hopsu-Havu VK, et al. Antisense RNA inhibition of cathepsin L expression reduces tumorigenicity of malignant cells. Eur J Cancer. 2000;36:787–795.
Article CAS Google Scholar
- Chapman HA, Riese JP, Shi GP . Emerging roles for cysteine proteases in human biology. Annu Rev Physiol. 1997;59:63–88.
Article CAS Google Scholar
- Kos J, Lah TT . Cysteine proteinases and their endogenous inhibitors target proteins for prognosis, diagnosis and therapy in cancer (review). Oncol Rep. 1998;5:1349–1361.
CAS PubMed Google Scholar
- Premzl A, Puizdar V, Zavašnik-Bergant V, et al. Invasion of _ras_-transformed breast epithelial cells depends on the proteolytic activity of cysteine and aspartic proteinases. Biol Chem. 2001;382:853–858.
Article CAS Google Scholar
- Krueger S, Kellner U, Buehling F, et al. Cathepsin L antisense oligonucleotides in a human osteosarcoma cell line: effects on the invasive phenotypes. Cancer Gene Ther. 2001;8:522–528.
Article CAS Google Scholar
- Kondraganti S, Mohanam S, Chintala SK, et al. Selective suppression of matrix metalloproteinase-9 in human glioblastoma cells by antisense gene transfer impairs glioblastoma cell invasion. Cancer Res. 2000;60:6851–6855.
CAS PubMed Google Scholar
- Rossi M, Rooprai H, Maidment SL, et al. The influence of sequential, in vitro passages on secretion of matrix metalloproteinases by human brain tumour cells. Anticancer Res. 1996;16:121–128.
CAS PubMed Google Scholar
- Gladson CL, Pijuan-Thompson V, Olman MA, et al. Upregulation of urikinase and urokinase receptor genes in malignant astrocytoma. Am J Pathol. 1995;146:1150–1160.
CAS PubMed PubMed Central Google Scholar
- Wick W, Wagner S, Kerkau S, et al. Bcl-2 promotes migration and invasiveness of human glioma cells. FEBS Lett. 1998;440:419–424.
Article CAS Google Scholar
- Zhu DM, Uckun FM . Z-Phe-Gly-NHO-Bz, an inhibitor of cysteine cathepsins, induces apoptosis in human cancer cells. Clin Cancer Res. 2000;6:2064–2069.
CAS PubMed Google Scholar
- Tobin DJ, Foitzik K, Reinheckel T, et al. The lysosomal protease cathepsin L is an important regulator of keratinocyte and melanocyte differentiation during hair follicle morphogenesis and cycling. Am J Pathol. 2002;160:1807–1821.
Article CAS Google Scholar
- Felbor U, Kessler B, Mothes W, et al. Neuronal loss and brain atrophy in mice lacking cathepsins B and L. Proc Natl Acad Sci USA. 2002;99:7883–7888.
Article CAS Google Scholar
- Harbeck N, Alt U, Berger U, et al. Prognostic impact of proteolytic factors (urokinase-type plasminogen activator, plasminogen activator inhibitor-1, and cathepsins B, D, and L) in primary breast cancer reflects effects of adjuvant systemic therapy. Clin Cancer Res. 2001;7:2757–2764.
CAS PubMed Google Scholar
- Shibata M, Kanamori S, Isahara K, et al. Participation of cathepsins B and D in apoptosis of PC12 cells following serum deprivation. Biochem Biophys Res Commun. 1998;251:199–203.
Article CAS Google Scholar
- Isahara K, Ohsawa Y, Kanamori S, et al. Regulation of a novel pathway for cell death by lysosomal aspartic and cysteine proteinases. Neuroscience. 1999;91:233–249.
Article CAS Google Scholar
- Guicciardi ME, Deussing J, Miyoshi H, Kaufmann SH, Gores GJ . Cathepsin B contributes to TNF-α mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J Clin Invest. 2000;106:1127–1137.
Article CAS Google Scholar
- Kingham PJ, Pocock JM . Microglial secreted cathepsin B induces neuronal apoptosis. J Neurochem. 2001;76:1475–1484.
Article CAS Google Scholar
- Roberts LR, Kurosawa H, Bronk SF, et al. Cathepsin B contributes to bile-salt induced apoptosis of rat hepatocytes. Gastroenterology. 1997;113:1714–1726.
Article CAS Google Scholar
- Van Eijk M, de Groot C . Germinal center B cell apoptosis requires both caspase and cathepsin activity. J Immunol. 1999;163:2478–2482.
CAS PubMed Google Scholar
- Hishita T, Tada-Oikawa S, Tohyama K, et al. Caspase-3 activation by lysosomal enzymes in cytochrome _c_-independent apoptosis in myelodysplastic syndrome-derived cell line P39. Cancer Res. 2001;61:2878–2884.
CAS PubMed Google Scholar
- Ishisaka R, Utsumi T, Kanno T, et al. Participation of a cathepsin L-type protease in the activation of caspase-3. Cell Struct Funct. 1999;24:465–479.
Article CAS Google Scholar