Signaling revisited in acute promyelocytic leukemia (original) (raw)
Lapidot T, Pflumio F, Doedens M, Murdoch B, Williams DE, Dick JE . Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice Science 1992 255: 1137–1141 CASPubMed Google Scholar
Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J, Minden M, Paterson B, Caligiuri MA, Dick JE . A cell initiating human acute myeloid leukaemia after transplantation into SCID mice Nature 1994 367: 645–648 ArticleCASPubMed Google Scholar
Sirard C, Lapidot T, Vormoor J, Cashman JD, Doedens M, Murdoch B, Jamal N, Messner H, Addey L, Minden M, Laraya P, Keating A, Eaves A, Lansdorp PM, Eaves CJ, Dick JE . Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis Blood 1996 87: 1539–1548 CASPubMed Google Scholar
Ida K, Kitabayashi I, Taki T, Taniwaki M, Noro K, Yamamoto M, Ohki M, Hayashi Y . Adenoviral E1A-associated protein p300 is involved in acute myeloid leukemia with t(11;22)(q23;q13) Blood 1997 90: 4699–4704 CASPubMed Google Scholar
Look AT . Oncogenic transcription factors in the human acute leukemias Science 1997 278: 1059–1064 CASPubMed Google Scholar
Pabst T, Mueller BU, Zhang P, Radomska HS, Narravula S, Schnittger S, Behre G, Hiddemann W, Tenen DG . Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia Nat Genet 2001 27: 263–270 CASPubMed Google Scholar
Grisolano JL, Wesselschmidt RL, Pelicci PG, Ley TJ . Altered myeloid development and acute leukemia in transgenic mice expressing PML-RAR alpha under control of cathepsin G regulatory sequences Blood 1997 89: 376–387 CASPubMed Google Scholar
He LZ, Tribioli C, Rivi R, Peruzzi D, Pelicci PG, Soares V, Cattoretti G, Pandolfi PP . Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice Proc Natl Acad Sci USA 1997 94: 5302–5307 CASPubMedPubMed Central Google Scholar
Okuda T, Cai Z, Yang S, Lenny N, Lyu CJ, van Deursen JM, Harada H, Downing JR . Expression of a knocked-in AML1-ETO leukemia gene inhibits the establishment of normal definitive hematopoiesis and directly generates dysplastic hematopoietic progenitors Blood 1998 91: 3134–3143 CASPubMed Google Scholar
Castilla LH, Garrett L, Adya N, Orlic D, Dutra A, Anderson S, Owens J, Eckhaus M, Bodine D, Liu PP . The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia Nat Genet 1999 23: 144–146 CASPubMed Google Scholar
Rhoades KL, Hetherington CJ, Harakawa N, Yergeau DA, Zhou L, Liu LQ, Little MT, Tenen DG, Zhang DE . Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model Blood 2000 96: 2108–2115 CASPubMed Google Scholar
Yokota S, Kiyoi H, Nakao M, Iwai T, Misawa S, Okuda T, Sonoda Y, Abe T, Kahsima K, Matsuo Y, Naoe T . Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines Leukemia 1997 11: 1605–1609 CASPubMed Google Scholar
Yamamoto Y, Kiyoi H, Nakano Y, Suzuki R, Kodera Y, Miyawaki S, Asou N, Kuriyama K, Yagasaki F, Shimazaki C, Akiyama H, Saito K, Nishimura M, Motoji T, Shinagawa K, Takeshita A, Saito H, Ueda R, Ohno R, Naoe T . Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies Blood 2001 97: 2434–2439 CASPubMed Google Scholar
Dash A, Gilliland DG . Molecular genetics of acute myeloid leukaemia Best Pract Res Clin Haematol 2001 14: 49–64 CASPubMed Google Scholar
Gishizky ML, Witte ON . Initiation of deregulated growth of multipotent progenitor cells by bcr- abl in vitroScience 1992 256: 836–839 CASPubMed Google Scholar
Cook WD, Metcalf D, Nicola NA, Burgess AW, Walker F . Malignant transformation of a growth factor-dependent myeloid cell line by Abelson virus without evidence of an autocrine mechanism Cell 1985 41: 677–683 CASPubMed Google Scholar
Daley GQ, Baltimore D . Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein Proc Natl Acad Sci USA 1988 85: 9312–9316 CASPubMedPubMed Central Google Scholar
Tobal K, Pagliuca A, Bhatt B, Bailey N, Layton DM, Mufti GJ . Mutation of the human FMS gene (M-CSF receptor) in myelodysplastic syndromes and acute myeloid leukemia Leukemia 1990 4: 486–489 CASPubMed Google Scholar
Dosil M, Wang S, Lemischka IR . Mitogenic signalling and substrate specificity of the Flk2/Flt3 receptor tyrosine kinase in fibroblasts and interleukin 3-dependent hematopoietic cells Mol Cell Biol 1993 13: 6572–6585 CASPubMedPubMed Central Google Scholar
Reuter CW, Morgan MA, Bergmann L . Targeting the Ras signaling pathway: a rational, mechanism-based treatment for hematologic malignancies? Blood 2000 96: 1655–1669 CASPubMed Google Scholar
Kelly LM, Liu Q, Kutok JL, Williams IR, Boulton CL, Gilliland DG . FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model Blood 2002 99: 310–318 CASPubMed Google Scholar
Birkenkamp KU, Geugien M, Lemmink HH, Kruijer W, Vellenga E . Regulation of constitutive STAT5 phosphorylation in acute myeloid leukemia blasts Leukemia 2001 15: 1923–1931 CASPubMed Google Scholar
Srinivasa SP, Doshi PD . Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways cooperate in mediating cytokine-induced proliferation of a leukemic cell line Leukemia 2002 16: 244–253 CASPubMed Google Scholar
Dong F, Hoefsloot LH, Schelen AM, Broeders CA, Meijer Y, Veerman AJ, Touw IP, Lowenberg B . Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia Proc Natl Acad Sci USA 1994 91: 4480–4484 CASPubMedPubMed Central Google Scholar
Dong F, Brynes RK, Tidow N, Welte K, Lowenberg B, Touw IP . Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia N Engl J Med 1995 333: 487–493 CASPubMed Google Scholar
Welte K, Gabrilove J, Bronchud MH, Platzer E, Morstyn G . Filgrastim (r-metHuG-CSF): the first 10 years Blood 1996 88: 1907–1929 CASPubMed Google Scholar
Tidow N, Pilz C, Teichmann B, Muller-Brechlin A, Germeshausen M, Kasper B, Rauprich P, Sykora KW, Welte K . Clinical relevance of point mutations in the cytoplasmic domain of the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia Blood 1997 89: 2369–2375 CASPubMed Google Scholar
Touw IP, Dong F . Severe congenital neutropenia terminating in acute myeloid leukemia: disease progression associated with mutations in the granulocyte-colony stimulating factor receptor gene Leuk Res 1996 20: 629–631 CASPubMed Google Scholar
Dale DC, Bonilla MA, Davis MW, Nakanishi AM, Hammond WP, Kurtzberg J, Wang W, Jakubowski A, Winton E, Lalezari P . A randomized controlled phase III trial of recombinant human granulocyte colony-stimulating factor (filgrastim) for treatment of severe chronic neutropenia Blood 1993 81: 2496–2502 CASPubMed Google Scholar
Hunter MG, Avalos BR . Deletion of a critical internalization domain in the G-CSFR in acute myelogenous leukemia preceded by severe congenital neutropenia Blood 1999 93: 440–446 CASPubMed Google Scholar
Da Silva N, Meyer-Monard S, Menot ML, Parrado A, Lebel A, Balitrand N, Fenaux P, Miclea JM, Rousselot P, Degos L, Dombret H, Chomienne C . Functional G-CSF pathways in t(8;21) leukemic cells allow for differentiation induction and degradation of AML1-ETO Hematol J 2000 1: 316–328 CASPubMed Google Scholar
Golub TR, Barker GF, Lovett M, Gilliland DG . Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation Cell 1994 77: 307–316 CASPubMed Google Scholar
Sawyers CL . Molecular abnormalities in myeloid leukemias and myelodysplastic syndromes Leuk Res 1998 22: 1113–1122 CASPubMed Google Scholar
Bourgeade MF, Defachelles AS, Cayre YE . Myc is essential for transformation by TEL/platelet-derived growth factor receptor beta (PDGFRbeta) Blood 1998 91: 3333–3339 CASPubMed Google Scholar
Papadopoulos P, Ridge SA, Boucher CA, Stocking C, Wiedemann LM . The novel activation of ABL by fusion to an ets-related gene, TEL Cancer Res 1995 55: 34–38 CASPubMed Google Scholar
Golub TR, Goga A, Barker GF, Afar DE, McLaughlin J, Bohlander SK, Rowley JD, Witte ON, Gilliland DG . Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia Mol Cell Biol 1996 16: 4107–4116 CASPubMedPubMed Central Google Scholar
Bollag G, Clapp DW, Shih S, Adler F, Zhang YY, Thompson P, Lange BJ, Freedman MH, McCormick F, Jacks T, Shannon K . Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells Nat Genet 1996 12: 144–148 CASPubMed Google Scholar
Largaespada DA, Brannan CI, Jenkins NA, Copeland NG . Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia Nat Genet 1996 12: 137–143 CASPubMed Google Scholar
Melnick A, Licht JD . Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia Blood 1999 93: 3167–3215 CASPubMed Google Scholar
Zelent A, Guidez F, Melnick A, Waxman S, Licht JD . Translocations of the RARalpha gene in acute promyelocytic leukemia Oncogene 2001 20: 7186–7203 CASPubMed Google Scholar
Chambon P . A decade of molecular biology of retinoic acid receptors FASEB J 1996 10: 940–954 CASPubMed Google Scholar
Douer D, Ramezani L, Parker J, Levine AM . All-_trans_-retinoic acid effects the growth, differentiation and apoptosis of normal human myeloid progenitors derived from purified CD34+ bone marrow cells Leukemia 2000 14: 874–881 CASPubMed Google Scholar
Kastner P, Chan S . Function of RARalpha during the maturation of neutrophils Oncogene 2001 20: 7178–7185 CASPubMed Google Scholar
Wang ZG, Delva L, Gaboli M, Rivi R, Giorgio M, Cordon-Cardo C, Grosveld F, Pandolfi PP . Role of PML in cell growth and the retinoic acid pathway Science 1998 279: 1547–1551 CASPubMed Google Scholar
Quignon F, De Bels F, Koken M, Feunteun J, Ameisen JC, de The H . PML induces a novel caspase-independent death process Nat Genet 1998 20: 259–265 CASPubMed Google Scholar
Pearson M, Pelicci PG . PML interaction with p53 and its role in apoptosis and replicative senescence Oncogene 2001 20: 7250–7256 CASPubMed Google Scholar
Barna M, Hawe N, Niswander L, Pandolfi PP . Plzf regulates limb and axial skeletal patterning Nat Genet 2000 25: 166–172 CASPubMed Google Scholar
Rowley JD, Golomb HM, Dougherty C . 15/17 translocation, a consistent chromosomal change in acute promyelocytic leukaemia Lancet 1977 1: 549–550 CASPubMed Google Scholar
Huang ME, Ye YC, Chen SR, Chai JR, Lu JX, Zhoa L, Gu LJ, Wang ZY . Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia Blood 1988 72: 567–572 CASPubMed Google Scholar
Castaigne S, Chomienne C, Daniel MT, Ballerini P, Berger R, Fenaux P, Degos L . All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results Blood 1990 76: 1704–1709 CASPubMed Google Scholar
Chomienne C, Ballerini P, Balitrand N, Daniel MT, Fenaux P, Castaigne S, Degos L . All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure–function relationship Blood 1990 76: 1710–1717 CASPubMed Google Scholar
Warrell RP Jr, Frankel SR, Miller WH Jr, Scheinberg DA, Itri LM, Hittelman WN, Vyas R, Andreeff M, Tafuri A, Jakubowski A, Gabrilove J, Gordon MS, Dmitrovsky E . Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid) N Engl J Med 1991 324: 1385–1393 PubMed Google Scholar
He LZ, Merghoub T, Pandolfi PP . In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications Oncogene 1999 18: 5278–5292 CASPubMed Google Scholar
Kogan SC, Bishop JM . Acute promyelocytic leukemia: from treatment to genetics and back Oncogene 1999 18: 5261–5267 CASPubMed Google Scholar
Pollock JL, Westervelt P, Kurichety AK, Pelicci PG, Grisolano JL, Ley TJ . A bcr-3 isoform of RARalpha-PML potentiates the development of PML- RARalpha-driven acute promyelocytic leukemia Proc Natl Acad Sci USA 1999 96: 15103–15108 CASPubMedPubMed Central Google Scholar
Kelly LM, Kutok JL, Williams IR, Boulton CL, Amaral SM, Curley DP, Ley TJ, Gilliland DG . PML/RARa and FLT3-ITD induce an APL-like disease in a mouse model Proc Natl Acad Sci USA 2002 99: 8283–8288 CASPubMedPubMed Central Google Scholar
Lin RJ, Egan DA, Evans RM . Molecular genetics of acute promyelocytic leukemia Trends Genet 1999 15: 179–184 CASPubMed Google Scholar
Benedetti L, Grignani F, Scicchitano BM, Jetten AM, Diverio D, Lo Coco F, Avvisati G, Gambacorti-Passerini C, Adamo S, Levin AA, Pelicci PG, Nervi C . Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RARalpha-mediated increase of type II transglutaminase Blood 1996 87: 1939–1950 CASPubMed Google Scholar
Eitan S, Schwartz M . A transglutaminase that converts interleukin-2 into a factor cytotoxic to oligodendrocytes Science 1993 261: 106–108 CASPubMed Google Scholar
Kojima S, Nara K, Rifkin DB . Requirement for transglutaminase in the activation of latent transforming growth factor-beta in bovine endothelial cells J Cell Biol 1993 121: 439–448 CASPubMed Google Scholar
Nakaoka H, Perez DM, Baek KJ, Das T, Husain A, Misono K, Im MJ, Graham RM . Gh: a GTP-binding protein with transglutaminase activity and receptor signaling function Science 1994 264: 1593–1596 CASPubMed Google Scholar
Fesus L, Thomazy V, Falus A . Induction and activation of tissue transglutaminase during programmed cell death FEBS Lett 1987 224: 104–108 CASPubMed Google Scholar
Joseph B, Lefebvre O, Mereau-Richard C, Danze PM, Belin-Plancot MT, Formstecher P . Evidence for the involvement of both retinoic acid receptor- and retinoic X receptor-dependent signaling pathways in the induction of tissue transglutaminase and apoptosis in the human myeloma cell line RPMI 8226 Blood 1998 91: 2423–2432 CASPubMed Google Scholar
Casini T, Pelicci PG . A function of p21 during promyelocytic leukemia cell differentiation independent of CDK inhibition and cell cycle arrest Oncogene 1999 18: 3235–3243 CASPubMed Google Scholar
Nervi C, Ferrara FF, Fanelli M, Rippo MR, Tomassini B, Ferrucci PF, Ruthardt M, Gelmetti V, Gambacorti-Passerini C, Diverio D, Grignani F, Pelicci PG, Testi R . Caspases mediate retinoic acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion protein Blood 1998 92: 2244–2251 CASPubMed Google Scholar
Kitareewan S, Pitha-Rowe I, Sekula D, Lowrey CH, Nemeth MJ, Golub TR, Freemantle SJ, Dmitrovsky E . UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia Proc Natl Acad Sci USA 2002 99: 3806–3811 CASPubMedPubMed Central Google Scholar
Yamanaka R, Lekstrom-Himes J, Barlow C, Wynshaw-Boris A, Xanthopoulos KG . CCAAT/enhancer binding proteins are critical components of the transcriptional regulation of hematopoiesis Int J Mol Med 1998 1: 213–221 CASPubMed Google Scholar
Park DJ, Chumakov AM, Vuong PT, Chih DY, Gombart AF, Miller WH Jr, Koeffler HP . CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment J Clin Invest 1999 103: 1399–1408 CASPubMedPubMed Central Google Scholar
Lanotte M, Martin-Thouvenin V, Najman S, Balerini P, Valensi F, Berger R . NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3) Blood 1991 77: 1080–1086 CASPubMed Google Scholar
Guibal FC, Moog-Lutz C, Smolewski P, Di Gioia Y, Darzynkiewicz Z, Lutz PG, Cayre YE . ASB-2 inhibits growth and promotes commitment in myeloid leukemia cells J Biol Chem 2002 277: 218–224 CASPubMed Google Scholar
Moog-Lutz C, Peterson EJ, Lutz PG, Eliason S, Cave-Riant F, Singer A, Di Gioia Y, Dmowski S, Kamens J, Cayre YE, Koretzky G . PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells J Biol Chem 2001 276: 22375–22381 CASPubMed Google Scholar
Kastner P, Lawrence HJ, Waltzinger C, Ghyselinck NB, Chambon P, Chan S . Positive and negative regulation of granulopoiesis by endogenous RARalpha Blood 2001 97: 1314–1320 CASPubMed Google Scholar
Tsai S, Collins SJ . A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage Proc Natl Acad Sci USA 1993 90: 7153–7157 CASPubMedPubMed Central Google Scholar
Tsai S, Bartelmez S, Sitnicka E, Collins S . Lymphohematopoietic progenitors immortalized by a retroviral vector harboring a dominant-negative retinoic acid receptor can recapitulate lymphoid, myeloid, and erythroid development Genes Dev 1994 8: 2831–2841 CASPubMed Google Scholar
Labbaye C, Valtieri M, Testa U, Giampaolo A, Meccia E, Sterpetti P, Parolini I, Pelosi E, Bulgarini D, Cayre YE . Retinoic acid downmodulates erythroid differentiation and GATA1 expression in purified adult-progenitor culture Blood 1994 83: 651–656 CASPubMed Google Scholar
Paul CC, Mahrer S, Tolbert M, Elbert BL, Wong I, Ackerman SJ, Baumann MA . Changing the differentiation program of hematopoietic cells: retinoic acid-induced shift of eosinophil-committed cells to neutrophils Blood 1995 86: 3737–3744 CASPubMed Google Scholar
Du C, Redner RL, Cooke MP, Lavau C . Overexpression of wild-type retinoic acid receptor alpha (RARalpha) recapitulates retinoic acid-sensitive transformation of primary myeloid progenitors by acute promyelocytic leukemia RARalpha-fusion genes Blood 1999 94: 793–802 CASPubMed Google Scholar
Johnson BS, Mueller L, Si J, Collins SJ . The cytokines IL-3 and GM-CSF regulate the transcriptional activity of retinoic acid receptors in different in vitro models of myeloid differentiation Blood 2002 99: 746–753 CASPubMed Google Scholar
Benoit G, Roussel M, Pendino F, Segal-Bendirdjian E, Lanotte M . Orchestration of multiple arrays of signal cross-talk and combinatorial interactions for maturation and cell death: another vision of t(15;17) preleukemic blast and APL-cell maturation Oncogene 2001 20: 7161–7177 CASPubMed Google Scholar
Gallagher RE, Lurie KJ, Leavitt RD, Wiernik PH . Effects of interferon and retinoic acid on the growth and differentiation of clonogenic leukemic cells from acute myelogenous leukemia patients treated with recombinant leukocyte-alpha A interferon Leuk Res 1987 11: 609–619 CASPubMed Google Scholar
Nason-Burchenal K, Gandini D, Botto M, Allopenna J, Seale JR, Cross NC, Goldman JM, Dmitrovsky E, Pandolfi PP . Interferon augments PML and PML/RAR alpha expression in normal myeloid and acute promyelocytic cells and cooperates with all-trans retinoic acid to induce maturation of a retinoid-resistant promyelocytic cell line Blood 1996 88: 3926–3936 CASPubMed Google Scholar
Gianni M, Terao M, Fortino I, LiCalzi M, Viggiano V, Barbui T, Rambaldi A, Garattini E . Stat1 is induced and activated by all-trans retinoic acid in acute promyelocytic leukemia cells Blood 1997 89: 1001–1012 CASPubMed Google Scholar
Kolla V, Weihua X, Kalvakolanu DV . Modulation of interferon action by retinoids. Induction of murine STAT1 gene expression by retinoic acid J Biol Chem 1997 272: 9742–9748 CASPubMed Google Scholar
Matikainen S, Lehtonen A, Sareneva T, Julkunen I . Regulation of IRF and STAT gene expression by retinoic acid Leuk Lymphoma 1998 30: 63–71 CASPubMed Google Scholar
Hall RE, Agarwal S, Kestler DP, Cobb JA, Goldstein KM, Chang NS . cDNA and genomic cloning and expression of the P48 monocytic differentiation/activation factor, a Mycoplasma fermentans gene product Biochem J 1996 319: 919–927 CASPubMedPubMed Central Google Scholar
Pelicano L, Li F, Schindler C, Chelbi-Alix MK . Retinoic acid enhances the expression of interferon-induced proteins: evidence for multiple mechanisms of action Oncogene 1997 15: 2349–2359 CASPubMed Google Scholar
Pelicano L, Brumpt C, Pitha PM, Chelbi-Alix MK . Retinoic acid resistance in NB4 APL cells is associated with lack of interferon alpha synthesis Stat1 and p48 induction Oncogene 1999 18: 3944–3953 CASPubMed Google Scholar
Dimberg A, Nilsson K, Oberg F . Phosphorylation-deficient Stat1 inhibits retinoic acid-induced differentiation and cell cycle arrest in U-937 monoblasts Blood 2000 96: 2870–2878 CASPubMed Google Scholar
Olsson IL, Breitman TR, Gallo RC . Priming of human myeloid leukemic cell lines HL-60 and U-937 with retinoic acid for differentiation effects of cyclic adenosine 3′:5′-monophosphate-inducing agents and a T-lymphocyte-derived differentiation factor Cancer Res 1982 42: 3928–3933 CASPubMed Google Scholar
Ruchaud S, Duprez E, Gendron MC, Houge G, Genieser HG, Jastorff B, Doskeland SO, Lanotte M . Two distinctly regulated events, priming and triggering, during retinoid-induced maturation and resistance of NB4 promyelocytic leukemia cell line Proc Natl Acad Sci USA 1994 91: 8428–8432 CASPubMedPubMed Central Google Scholar
Deshpande RV, Peterson RH, Moore MA . Granulocyte colony-stimulating factor activates protein kinase A in granulocytic but not monocytic precursors or neutrophils J Interferon Cytokine Res 1998 18: 579–586 CASPubMed Google Scholar
Benoit G, Altucci L, Flexor M, Ruchaud S, Lillehaug J, Raffelsberger W, Gronemeyer H, Lanotte M . RAR-independent RXR signaling induces t(15;17) leukemia cell maturation EMBO J 1999 18: 7011–7018 CASPubMedPubMed Central Google Scholar
Zhu Q, Zhang JW, Zhu HQ, Shen YL, Flexor M, Jia PM, Yu Y, Cai X, Waxman S, Lanotte M, Chen SJ, Chen Z, Tong JH . Synergic effects of arsenic trioxide and cAMP during acute promyelocytic leukemia cell maturation subtends a novel signaling cross- talk Blood 2002 99: 1014–1022 CASPubMed Google Scholar
Spiekermann K, Biethahn S, Wilde S, Hiddemann W, Alves F . Constitutive activation of STAT transcription factors in acute myelogenous leukemia Eur J Haematol 2001 67: 63–71 CASPubMed Google Scholar
Tkatch LS, Rubin KA, Ziegler SF, Tweardy DJ . Modulation of human G-CSF receptor mRNA and protein in normal and leukemic myeloid cells by G-CSF and retinoic acid J Leukoc Biol 1995 57: 964–971 CASPubMed Google Scholar
Gianni M, Terao M, Zanotta S, Barbui T, Rambaldi A, Garattini E . Retinoic acid and granulocyte colony-stimulating factor synergistically induce leukocyte alkaline phosphatase in acute promyelocytic leukemia cells Blood 1994 83: 1909–1921 CASPubMed Google Scholar
Smeland EB, Rusten L, Jacobsen SE, Skrede B, Blomhoff R, Wang MY, Funderud S, Kvalheim G, Blomhoff HK . All-trans retinoic acid directly inhibits granulocyte colony-stimulating factor-induced proliferation of CD34+ human hematopoietic progenitor cells Blood 1994 84: 2940–2945 CASPubMed Google Scholar
Miyauchi J . All-trans retinoic acid and hematopoietic growth factors regulating the growth and differentiation of blast progenitors in acute promyelocytic leukemia Leuk Lymphoma 1999 33: 267–280 CASPubMed Google Scholar
Kishi K, Toba K, Azegami T, Tsukada N, Uesugi Y, Masuko M, Niwano H, Hashimoto S, Sakaue M, Furukawa T, Koike T, Takahashi H, Maekawa T, Abe T, Aizawa Y . Hematopoietic cytokine-dependent differentiation to eosinophils and neutrophils in a newly established acute promyelocytic leukemia cell line with t(15;17) Exp Hematol 1998 26: 135–142 CASPubMed Google Scholar
Shimodaira S, Kitano K, Nishizawa Y, Ichikawa N, Ishida F, Kamino I, Matsui H, Kiyosawa K . Acute myelogenous leukemia with a t(2;17;4)(p13;q21;p16) aberration: effective treatment with all-trans retinoic acid and granulocyte colony-stimulating factor J Intern Med 1999 38: 150–154 CAS Google Scholar
Jansen JH, de Ridder MC, Geertsma WM, Erpelinck CA, van Lom K, Smit EM, Slater R, vd Reijden BA, de Greef GE, Sonneveld P, Lowenberg B . Complete remission of t(11;17) positive acute promyelocytic leukemia induced by all-trans retinoic acid and granulocyte colony-stimulating factor Blood 1999 94: 39–45 CASPubMed Google Scholar
Corey SJ, Burkhardt AL, Bolen JB, Geahlen RL, Tkatch LS, Tweardy DJ . Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases Proc Natl Acad Sci USA 1994 91: 4683–4687 CASPubMedPubMed Central Google Scholar