Wolf ML, Weng WK, Stieglbauer KT, Shah N, LeBien TW . Functional effect of IL-7-enhanced CD19 expression on human B cell precursors. J Immunol 1993; 151: 138–148. CASPubMed Google Scholar
Billips LG, Nunez CA, Bertrand FE, Stankovic AK, Gartland GL, Burrows PD et al. Immunoglobulin recombinase gene activity is modulated reciprocally by interleukin 7 and CD19 in B cell progenitors. J Exp Med 1995; 182: 973–982. ArticleCAS Google Scholar
Bertrand FE, Billips LG, Burrows PD, Gartland GL, Kubagawa H, Schroeder Jr HW . Ig D(H) gene segment transcription and rearrangement before surface expression of the pan-B-cell marker CD19 in normal human bone marrow. Blood 1997; 90: 736–744. CASPubMed Google Scholar
Gathings WE, Lawton AR, Cooper MD . Immunofluorescent studies of the development of pre-B cells, B lymphocytes and immunoglobulin isotype diversity in humans. Eur J Immunol 1977; 7: 804–810. ArticleCAS Google Scholar
Lassoued K, Nunez CA, Billips L, Kubagawa H, Monteiro RC, LeBien TW et al. Expression of surrogate light chain receptors is restricted to a late stage in pre-B cell differentiation. Cell 1993; 73: 73–86. ArticleCAS Google Scholar
Burrows PD, Stephan RP, Wang YH, Lassoued K, Zhang Z, Cooper MD . The transient expression of pre-B cell receptors governs B cell development. Semin Immunol 2002; 14: 343–349. ArticleCAS Google Scholar
Wormann B, Anderson JM, Liberty JA, Gajl-Peczalska K, Brunning RD, Silberman TL et al. Establishment of a leukemic cell model for studying human pre B to B cell differentiation. J Immunol 1989; 142: 110–117. CASPubMed Google Scholar
Bertrand FE, Vogtenhuber C, Shah N, LeBien TW . Pro-B cell to pre-B cell development in B-lineage acute lymphoblastic leukemia. Blood 2001; 98: 3398–3405. ArticleCAS Google Scholar
Wang YH, Zhang Z, Burrows PD, Kubagawa H, Bridges Jr SL, Findley HW et al. V(D)J recombinatorial repertoire diversification during intraclonal pro-B to B-cell differentiation. Blood 2003; 101: 1030–1037. ArticleCAS Google Scholar
Greaves M . Molecular genetics, natural history and the demise of childhood leukaemia. Eur J Cancer 1999; 35: 173–185. ArticleCAS Google Scholar
DiMarino JF, Cleary ML . MLL rearrangements in haematological malignancies: lessons from clinical and biological studies. Br J Haematol 1999; 106: 614–626. Article Google Scholar
Stong RC, Korsmeyer SJ, Parkin JL, Arthur DC, Kersey JH . Human acute leukemia cell line with the t(4;11) chromosomal rearrangement exhibits B lineage and monocytic characteristics. Blood 1985; 65: 21–31. CASPubMed Google Scholar
Yu BD, Hess JL, Horning SE, Brown GA, Korsmeyer SJ . Altered Hox expression and segmental identity in Mll-mutant mice. Nature 1995; 378: 505–508. ArticleCAS Google Scholar
Yu BD, Hanson RD, Hess JL, Horning SE, Korsmeyer SJ . MLL, a mammalian trithorax group gene functions as a transcriptional maintenance factor in morphogenesis. Proc Natl Acad Sci USA 1998; 95: 10632–10636. ArticleCAS Google Scholar
Milne TA, Briggs SD, Brock HW, Martin ME, Gibbs D, Allis CD et al. MLL targets SET domain methyltransferase activity to Hox gene promoters. Mol Cell 2002; 10: 1107–1117. ArticleCAS Google Scholar
So CW, Lin M, Ayton PM, Chen EH, Cleary ML . Dimerization contributes to oncogenic activation of MLL chimeras in actue leukemias. Cancer Cell 2003; 4: 99–110. ArticleCAS Google Scholar
Isnard P, Core N, Naquet P, Djabali M . Altered lymphoid development in mice deficient for the mAF4 proto-oncogene. Blood 2000; 96: 705–710. CASPubMed Google Scholar
Dobson CL, Warren AJ, Pannel R, Forster A, Rabbitts TH . Tumorigenesis in mice with a fusion of the leukemia oncogene MLL and the bacterial lacZ gene. EMBO J 2000; 19: 843–851. ArticleCAS Google Scholar
Collins EC, Rabbitts TH . The promiscuous MLL gene links chromosomal translocations to cellular differentiation and tumor tropism. Trends Mol Med 2002; 8: 436–442. ArticleCAS Google Scholar
Armstrong SA, Staunton JE, Silverman LB, Pieters R, den Boer ML, Minden MD et al. MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia. Nat Genet 2002; 1: 41–47. Google Scholar
Yeoh EJ, Ross ME, Shurtleff SA, Williams WK, Patel D, Mahfouz R et al. Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell 2002; 1: 133–143. ArticleCAS Google Scholar
Magli MC, Largman C, Lawrence HJ . Effects of HOX homeobox genes in blood cell differentiation. J Cell Phys 1997; 173: 168–177. ArticleCAS Google Scholar
Cillo C, Cantile M, Faiella A, Boncinelli E . Homeobox genes in normal and malignant cells. J Cell Phys 2001; 188: 161–169. ArticleCAS Google Scholar
Apiou F, Flagiello D, Cillo C, Malfoy B, Poupon MF, Dutrillaux B . Fine mapping of human HOX gene clusters. Cytogenet Cell Genet 1996; 73: 114–115. ArticleCAS Google Scholar
Acampora D, D'sposito M, Faiella A, Pannese M, Migliaccio E, Morelli F et al. The human HOX gene family. Nucleic Acids Res 1989; 17: 10385–10402. ArticleCAS Google Scholar
Sauvageau G, Lansdorp PM, Eaves CJ, Hogge DE, Dragowska WH, Reid DS et al. Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. Proc Natl Acad Sci USA 1994; 91: 12223–12227. ArticleCAS Google Scholar
Lawrence HJ, Sauvageau G, Ahmadi N, Lopez AR, LeBeau MM, Link M et al. Stage- and lineage-specific expression of the HOXA10 homeobox gene in normal and leukemic hematopoietic cells. Exp Hematol 1995; 23: 1160–1166. CASPubMed Google Scholar
Blatt C, Loten J, Sachs L . Inhibition of specific pathways of myeloid cell differentiation by an activated HOX 2.4 homeobox gene. Cell Growth Differ 1992; 3: 671–676. CASPubMed Google Scholar
Lill MC, Fuller JF, Herzig R, Crooks GM, Gasson JC . The role of the homeobox gene, HOX B7, in human myelomonocytic differentiation. Blood 1995; 85: 692–697. CASPubMed Google Scholar
Lawrence HJ, Helgason CD, Sauvageau G, Fong S, Izon DJ, Humphries RK et al. Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis. Blood 1997; 89: 1922–1930. CASPubMed Google Scholar
Thorsteinsdottir U, Mamo A, Kroon E, Jerome L, Bijl J, Lawrence J et al. Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion. Blood 2002; 99: 121–129. ArticleCAS Google Scholar
Pocock CF, Malone M, Booth M, Evans M, Morgan G, Greil J et al. BCL-2 expression by leukaemic blasts in a SCID mouse model of biphenotypic leukaemia associated with the t(4;11)(q21;q23) translocation. Br J Haematol 1995; 90: 855–867. ArticleCAS Google Scholar
Afonja O, Smith Jr JE, Cheng DM, Goldenberg AS, Amorosi E, Shimamoto T et al. MEIS1 and HOXA7 genes in human acute myeloid leukemia. Leukemia 2000; 24: 849–855. ArticleCAS Google Scholar
Drabkin HA, Parsy C, Ferguson K, Guilhot F, Lacotte L, Roy L et al. Quantitative HOX expression in chromosomally defined subsets of acute myelogenous leukemia. Leukemia 2002; 16: 186–195. ArticleCAS Google Scholar
Hanson RD, Hess JL, Yu BD, Ernst P, van Lohuizen M, Berns A et al. Mammalian trithorax polycomb-group homologues are antagonistic regulators of homeotic development. Proc Natl Acad Sci USA 1999; 96: 14372–14377. ArticleCAS Google Scholar
Kroon E, Krosl J, Thorsteinsdottir U, Baban S, Buchberg AM, Sauvageau G . Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J 1998; 17: 3714–3725. ArticleCAS Google Scholar
Shen W-F, Rozenfeld S, Kwong A, Komuves LG, Lawrence HJ, Largman C . HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells. Mol Cell Biol 1999; 19: 3051–3061. ArticleCAS Google Scholar
Thorsteinsdottir U, Kroon E, Jerome L, Blasi F, Sauvageau G . Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia. Mol Cell Biol 2001; 21: 224–234. ArticleCAS Google Scholar
Calvo KR, Knoepfler PS, Sykes DB, Pasillas MP, Kamps MP . Meis1a suppresses differentiation by G-CSF and promotes proliferation by SCF: potential mechanisms of cooperativity with Hoxa9 in myeloid leukemia. Proc Natl Acad Sci USA 2001; 98: 13120–13125. ArticleCAS Google Scholar
Ferrando AA, Armstrong SA, Neuberg DS, Sallan SE, Silverman LB, Korsmeyer SJ et al. Gene expression signatures in _MLL_-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation. Blood 2003; 102: 262–268. ArticleCAS Google Scholar
Foucher I, Volovitch M, Frain M, Kim JJ, Souberbielle JC, Gan L et al. Hoxa5 overexpression correlates with IGFBP1 upregulation and postnatal dwarfism: evidence for an interaction between Hoxa5 and Forkhead box transcription factors. Development 2002; 129: 4065–4074. CASPubMed Google Scholar
Kim JJ, Taylor HS, Akbas GE, Foucher I, Trembleau A, Jaffe RC et al. Regulation of insulin-like growth factor binding protein-1 promoter activity by FKHR and HOXA10 in primate endometrial cells. Biol Reprod 2003; 68: 24–30. ArticleCAS Google Scholar