Stress-induced alternative splicing of acetylcholinesterase results in enhanced fear memory and long-term potentiation (original) (raw)

• Kim JJ, Diamond DM . The stressed hippocampus, synaptic plasticity, lost memories. Nat Rev Neurosci 2002; 3: 453–462.
  Article CAS Google Scholar
• McEwen BS . Corticosteroids and hippocampal plasticity. Ann NY Acad Sci 1994; 746: 134–142.
  Article CAS Google Scholar
• Wilson MA, McNaughton BL . Dynamics of the hippocampal ensemble code for space. Science 1993; 261: 1055–1058.
  Article CAS Google Scholar
• Rolls ET, Stringer SM, Trappenberg TP . A unified model of spatial and episodic memory. Proc R Soc Lond B Biol Sci 2002; 269: 1087–1093.
  Article Google Scholar
• Huerta PT, Sun LD, Wilson MA, Tonegawa S . Formation of temporal memory requires NMDA receptors within CA1 pyramidal neurons. Neuron 2000; 25: 473–480.
  Article CAS Google Scholar
• Phillips RG, LeDoux JE . Lesions of the dorsal hippocampal formation interfere with background but not foreground contextual fear conditioning. Learn. Mem. 1994; 1: 34–44.
  CAS PubMed Google Scholar
• Jensen O, Lisman JE . Position reconstruction from an ensemble of hippocampal place cells: contribution of theta phase coding. J Neurophysiol 2000; 83: 2602–2609.
  Article CAS Google Scholar
• Moita MA, Rosis S, Zhou Y, LeDoux JE, Blair HT . Hippocampal place cells acquire location-specific responses to the conditioned stimulus during auditory fear conditioning. Neuron 2003; 37: 485–497.
  Article CAS Google Scholar
• Barrientos RM, O'Reilly RC, Rudy JW . Memory for context is impaired by injecting anisomycin into dorsal hippocampus following context exploration. Behav Brain Res 2002; 134: 299–306.
  Article Google Scholar
• Sanders MJ, Wiltgen BJ, Fanselow MS . The place of the hippocampus in fear conditioning. Eur J Pharmacol 2003; 463: 217–223.
  Article CAS Google Scholar
• Xu L, Holscher C, Anwyl R, Rowan MJ . Glucocorticoid receptor and protein/RNA synthesis-dependent mechanisms underlie the control of synaptic plasticity by stress. Proc Natl Acad Sci USA 1998; 95: 3204–3208.
  Article CAS Google Scholar
• Cullinan WE, Herman JP, Battaglia DF, Akil H, Watson SJ . Pattern and time course of immediate early gene expression in rat brain following acute stress. Neuroscience 1995; 64: 477–505.
  Article CAS Google Scholar
• Kaufer D, Friedman A, Seidman S, Soreq H . Acute stress facilitates long-lasting changes in cholinergic gene expression. Nature 1998; 393: 373–377.
  Article CAS Google Scholar
• Meshorer E et al. Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity. Science 2002; 295: 508–512.
  Article CAS Google Scholar
• Cohen O et al. Overexpression of ‘readthrough’ acetylcholinesterase is associated with antisense suppressible behavioral impairments. Mol Psychiatry 2002; 7: 874–885.
  Article CAS Google Scholar
• Birikh K, Sklan E, Shoham S, Soreq H . Interaction of ‘Readthrough’ acetylcholinesterase with RACK1 PKC_β_II correlates with intensified fear induced conflict behavior. Proc Natl Acad Sci USA 2003; 100: 283–288.
  Article CAS Google Scholar
• Soreq H, Seidman S . Acetylcholinesterase–new roles for an old actor. Nat Rev Neurosci 2001; 2: 294–302.
  Article CAS Google Scholar
• Blank T, Nijholt I, Eckart K, Spiess J . Priming of long-term potentiation in mouse hippocampus by corticotropin-releasing factor acute stress: implications for hippocampus-dependent learning. J Neurosci 2002; 22: 3788–3794.
  Article CAS Google Scholar
• Franklin KBJ, Paxinos G In: The mouse brain in stereotaxic coordinates. Academic Press: San Diego, 1997.
  Google Scholar
• Nijholt I, Blank T, Ahi J, Spiess J . In vivo CREB phosphorylation mediated by dopamine and NMDA receptor activation in mouse hippocampus and caudate nucleus. Brain Res Gene Expression Patterns 2002; 1: 101–106.
  Article CAS Google Scholar
• Sternfeld M et al. Excess ‘read-through’ acetylcholinesterase attenuates but the ‘synaptic’ variant intensifies neurodeterioration correlates. Proc Natl Acad Sci USA 2000; 97: 8647–8652.
  Article CAS Google Scholar
• Grisaru D et al. ARP, a peptide derived from the stress-associated acetylcholinesterase variant has hematopoietic growth promoting activities. Mol Med 2001; 7: 93–105.
  Article CAS Google Scholar
• Smith MA, Makino S, Kvetnansky R, Post RM . Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. J Neurosci 1995; 15: 1961–1970.
  Article Google Scholar
• Phillips R, LeDoux JE . Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav Neurosci 1992; 106: 274–285.
  Article CAS Google Scholar
• Kandel ER . The molecular biology of memory storage: a dialogue between genes and synapses. Science 2001; 294: 1030–1038.
  Article CAS Google Scholar
• Stanton PK . Transient protein kinase C activation primes long-term depression and suppresses long-term potentiation of synaptic transmission in hippocampus. Proc Natl Acad Sci USA 1995; 92: 1724–1728.
  Article CAS Google Scholar
• Weg-Remers S, Ponta H, Herrlich P, Konig H . Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway. The EMBO J 2001; 20: 4194–4203.
  Article CAS Google Scholar
• Schafe GE, Atkins CM, Swank MW, Bauer EP, Sweatt JD, LeDoux JE . Activation of ERK/MAP kinase in the amygdala is required for memory consolidation of pavlovian fear conditioning. J Neurosci 2000; 20: 8177–8187.
  Article CAS Google Scholar
• Sananbenesi F, Fischer A, Schrick C, Spiess J, Radulovic J . Phosphorylation of hippocampal Erk-1/2, Elk-1, and p90-Rsk-1 during contextual fear conditioning: interactions between Erk-1/2 and Elk-1. Mol Cell Neurosci 2002; 21: 463–476.
  Article CAS Google Scholar
• Perrier AI, Massoulie J, Krejci E . PRiMA: the membrane anchor of acetylcholinesterase in the brain. Neuron 2002; 33: 275–285.
  Article CAS Google Scholar
• Song JY, Ichtchenko K, Sudhof TC, Brose N . Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses. Proc Natl Acad Sci USA 1999; 96: 1100–1105.
  Article CAS Google Scholar
• Grifman M, Galyam N, Seidman S, Soreq H . Functional redundancy of acetylcholinesterase and neuroligin in mammalian neuritogenesis. Proc Natl Acad Sci USA 1998; 95: 13935–13940.
  Article CAS Google Scholar
• Scheiffele P, Fan J, Choih J, Fetter R, Serafini T . Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons. Cell 2000; 101: 657–669.
  Article CAS Google Scholar
• Ichtchenko K, Hata Y, Nguyen T, Ullrich B, Missler M, Moomaw C, Sudhof TC . Neuroligin-1 a splice site-specific ligand for beta-neurexins. Cell 1995; 81: 435–443.
  Article CAS Google Scholar
• Stillman MJ, Shukitt-Hale B, Coffey BP, Levy A, Lieberman HR . In vivo hippocampal acetylcholine release during exposure to acute stress. Stress 1997; 1: 191–200.
  Article CAS Google Scholar
• De Kloet ER, Oitzl MS, Joels M . Stress and cognition: are corticosteroids good or bad guys? Trends Neurosci 1999; 22: 422–426.
  Article CAS Google Scholar
• Young E, Cesena T, Meiri KF, Perrone-Bizzozero NI . Changes in protein kinase C (PKC) activity, isozyme translocation, and GAP-43 phosphorylation in the rat hippocampal formation after a single-trial contextual fear conditioning paradigm. Hippocampus 2002; 12: 457–464.
  Article CAS Google Scholar
• Weeber EJ et al. A role for the beta isoform of protein kinase C in fear conditioning. J Neurosci 2000; 20: 5906–5914.
  Article CAS Google Scholar
• Rosen JB, Schulkin J . From normal fear to pathological anxiety. Psychol Rev 1998; 105: 325–350.
  Article CAS Google Scholar
• Gorman J, Kent J, Sullivan G, Coplan J . Neuroanatomical hypothesis of panic disorder, revised. Am J Psych 2000; 157: 493–505.
  Article CAS Google Scholar
• Bouton ME, Mineka S, Barlow DH . A modern learning theory perspective on the etiology of panic disorder. Psychol Rev 2001; 108: 4–32.
  Article CAS Google Scholar