Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia (original) (raw)

• Attwooll C, Denchi EL, Helin K . (2004). The E2F family: specific functions and overlapping interests. EMBO J 23: 4709–4716.
  Article CAS Google Scholar
• Avni D, Yang H, Martelli F, Hofmann F, ElShamy WM, Ganesan S et al. (2003). Active localization of the retinoblastoma protein in chromatin and its response to S phase DNA damage. Mol Cell 12: 735–746.
  Article CAS Google Scholar
• Bindra RS, Gibson SL, Meng A, Westermark U, Jasin M, Pierce AJ et al. (2005). Hypoxia-induced down-regulation of BRCA1 expression by E2Fs. Cancer Res 65: 11597–11604.
  Article CAS Google Scholar
• Bindra RS, Schaffer PJ, Meng A, Woo J, Maseide K, Roth ME et al. (2004). Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells. Mol Cell Biol 24: 8504–8518.
  Article CAS Google Scholar
• Cam H, Dynlacht BD . (2003). Emerging roles for E2F: beyond the G1/S transition and DNA replication. Cancer Cell 3: 311–316.
  Article CAS Google Scholar
• Chowdhury D, Keogh MC, Ishii H, Peterson CL, Buratowski S, Lieberman J . (2005). gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair. Mol Cell 20: 801–809.
  Article CAS Google Scholar
• Cicchillitti L, Fasanaro P, Biglioli P, Capogrossi MC, Martelli F . (2003). Oxidative stress induces protein phosphatase 2A-dependent dephosphorylation of the pocket proteins pRb, p107, and p130. J Biol Chem 278: 19509–19517.
  Article CAS Google Scholar
• Classon M, Dyson N . (2001). p107 and p130: versatile proteins with interesting pockets. Exp Cell Res 264: 135–147.
  Article CAS Google Scholar
• Cobrinik D . (2005). Pocket proteins and cell cycle control. Oncogene 24: 2796–2809.
  Article CAS Google Scholar
• Coquelle A, Toledo F, Stern S, Bieth A, Debatisse M . (1998). A new role for hypoxia in tumor progression: induction of fragile site triggering genomic rearrangements and formation of complex DMs and HSRs. Mol Cell 2: 259–265.
  Article CAS Google Scholar
• DuPree EL, Mazumder S, Almasan A . (2004). Genotoxic stress induces expression of E2F4, leading to its association with p130 in prostate carcinoma cells. Cancer Res 64: 4390–4393.
  Article CAS Google Scholar
• Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB et al. (2005). Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 434: 917–921.
  Article CAS Google Scholar
• Garriga J, Jayaraman AL, Limon A, Jayadeva G, Sotillo E, Truongcao M et al. (2004). A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130. Cell Cycle 3: 1320–1330.
  Article CAS Google Scholar
• Hammond EM, Denko NC, Dorie MJ, Abraham RT, Giaccia AJ . (2002). Hypoxia links ATR and p53 through replication arrest. Mol Cell Biol 22: 1834–1843.
  Article CAS Google Scholar
• Harris AL . (2002). Hypoxia – a key regulatory factor in tumour growth. Nat Rev Cancer 2: 38–47.
  Article CAS Google Scholar
• Helt AM, Galloway DA . (2001). Destabilization of the retinoblastoma tumor suppressor by human papillomavirus type 16 E7 is not sufficient to overcome cell cycle arrest in human keratinocytes. J Virol 75: 6737–6747.
  Article CAS Google Scholar
• Iwanaga R, Komori H, Ohtani K . (2004). Differential regulation of expression of the mammalian DNA repair genes by growth stimulation. Oncogene 23: 8581–8590.
  Article CAS Google Scholar
• Kel AE, Kel-Margoulis OV, Farnham PJ, Bartley SM, Wingender E, Zhang MQ . (2001). Computer-assisted identification of cell cycle-related genes: new targets for E2F transcription factors. J Mol Biol 309: 99–120.
  Article CAS Google Scholar
• Koshiji M, Kageyama Y, Pete EA, Horikawa I, Barrett JC, Huang LE . (2004). HIF-1alpha induces cell cycle arrest by functionally counteracting Myc. EMBO J 23: 1949–1956.
  Article CAS Google Scholar
• Koshiji M, To KK, Hammer S, Kumamoto K, Harris AL, Modrich P et al. (2005). HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression. Mol Cell 17: 793–803.
  Article CAS Google Scholar
• Li CY, Little JB, Hu K, Zhang W, Zhang L, Dewhirst MW et al. (2001). Persistent genetic instability in cancer cells induced by non-DNA-damaging stress exposures. Cancer Res 61: 428–432.
  CAS PubMed Google Scholar
• Lin WC, Lin FT, Nevins JR . (2001). Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev 15: 1833–1844.
  CAS PubMed PubMed Central Google Scholar
• Meng AX, Jalali F, Cuddihy A, Chan N, Bindra RS, Glazer PM et al. (2005). Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells. Radiother Oncol 76: 168–176.
  Article CAS Google Scholar
• Mihaylova VT, Bindra RS, Yuan J, Campisi D, Narayanan L, Jensen R et al. (2003). Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells. Mol Cell Biol 23: 3265–3273.
  Article CAS Google Scholar
• North S, Moenner M, Bikfalvi A . (2005). Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors. Cancer Lett 218: 1–14.
  Article CAS Google Scholar
• Paquette B, Little JB . (1994). In vivo enhancement of genomic instability in minisatellite sequences of mouse C3H/10T1/2 cells transformed in vitro by X-rays. Cancer Res 54: 3173–3178.
  CAS PubMed Google Scholar
• Pediconi N, Ianari A, Costanzo A, Belloni L, Gallo R, Cimino L et al. (2003). Differential regulation of E2F1 apoptotic target genes in response to DNA damage. Nat Cell Biol 5: 552–558.
  Article CAS Google Scholar
• Reynolds TY, Rockwell S, Glazer PM . (1996). Genetic instability induced by the tumor microenvironment. Cancer Res 56: 5754–5757.
  CAS PubMed Google Scholar
• Roth ME, Feng L, McConnell KJ, Schaffer PJ, Guerra CE, Affourtit JP et al. (2004). Expression profiling using a hexamer-based universal microarray. Nat Biotechnol 22: 418–426.
  Article CAS Google Scholar
• Sandelin A, Alkema W, Engstrom P, Wasserman WW, Lenhard B . (2004). JASPAR: an open-access database for eukaryotic transcription factor binding profiles. Nucleic Acids Res 32: Database issue(D91–4.
• Stevens C, La Thangue NB . (2003). A new role for E2F-1 in checkpoint control. Cell Cycle 2: 435–437.
  Article CAS Google Scholar
• Stevens C, La Thangue NB . (2004). The emerging role of E2F-1 in the DNA damage response and checkpoint control. DNA Repair (Amsterdam) 3: 1071–1079.
  Article CAS Google Scholar
• Subarsky P, Hill RP . (2003). The hypoxic tumour microenvironment and metastatic progression. Clin Exp Metastasis 20: 237–250.
  Article CAS Google Scholar
• Thompson LH, Schild D . (2002). Recombinational DNA repair and human disease. Mutat Res 509: 49–78.
  Article CAS Google Scholar
• Voorhoeve PM, Watson RJ, Farlie PG, Bernards R, Lam EW . (1999). Rapid dephosphorylation of p107 following UV irradiation. Oncogene 18: 679–688.
  Article CAS Google Scholar
• Weinmann AS, Yan PS, Oberley MJ, Huang TH, Farnham PJ . (2002). Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis. Genes Dev 16: 235–244.
  Article CAS Google Scholar
• Wells J, Graveel CR, Bartley SM, Madore SJ, Farnham PJ . (2002). The identification of E2F1-specific target genes. Proc Natl Acad Sci USA 99: 3890–3895.
  Article CAS Google Scholar
• Young SD, Marshall RS, Hill RP . (1988). Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells. Proc Natl Acad Sci USA 85: 9533–9537.
  Article CAS Google Scholar
• Yuan J, Narayanan L, Rockwell S, Glazer PM . (2000). Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH. Cancer Res 60: 4372–4376.
  CAS PubMed Google Scholar
• Zhu W, Giangrande PH, Nevins JR . (2004). E2Fs link the control of G1/S and G2/M transcription. EMBO J 23: 4615–4626.
  Article CAS Google Scholar