Estrogen receptor-positive mammary tumorigenesis in TGFα transgenic mice progresses with progesterone receptor loss (original) (raw)

• Adan RA, Cox JJ, van Kats JP, Burbach JP . (1992). Thyroid hormone regulates the oxytocin gene. J Biol Chem 267: 3771–3777.
  CAS PubMed Google Scholar
• Amundadottir LT, Johnson MD, Merlino G, Smith GH, Dickson RB . (1995). Synergistic interaction of transforming growth factor alpha and c-myc in mouse mammary and salivary gland tumorigenesis. Cell Growth Differ 6: 737–748.
  CAS PubMed Google Scholar
• Arendt LM, Rose-Hellekant TA, Sandgren EP, Schuler LA . (2006). Prolactin potentiates transforming growth factor alpha induction of mammary neoplasia in transgenic mice. Am J Pathol 168: 1365–1374.
  Article CAS Google Scholar
• Arpino G, Weiss H, Lee AV, Schiff R, De Placido S, Osborne CK et al. (2005). Estrogen receptor-positive, progesterone receptor-negative breast cancer: association with growth factor receptor expression and tamoxifen resistance. J Natl Cancer Inst 97: 1254–1261.
  Article CAS Google Scholar
• Bieche I, Onody P, Tozlu S, Driouch K, Vidaud M, Lidereau R . (2003). Prognostic value of ERBB family mRNA expression in breast carcinomas. Int J Cancer 106: 758–765.
  Article CAS Google Scholar
• Blackburn AC, Brown JS, Naber SP, Otis CN, Wood JT, Jerry DJ . (2003). BALB/c alleles for Prkdc and Cdkn2a interact to modify tumor susceptibility in Trp53+/− mice. Cancer Res 63: 2364–2368.
  CAS PubMed Google Scholar
• Blackburn AC, Jerry DJ . (2002). Knockout and transgenic mice of Trp53: what have we learned about p53 in breast cancer. Breast Cancer Res 4: 101–111.
  Article CAS Google Scholar
• Brinster RL, Chen HY, Trumbauer ME, Yagle MK, Palmiter RD . (1985). Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs. Proc Natl Acad Sci USA 82: 4438–4442.
  Article CAS Google Scholar
• Creighton CJ, Hilger AM, Murthy S, Rae JM, Chinnaiyan AM, El-Ashry D . (2006). Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors. Cancer Res 66: 3903–3911.
  Article CAS Google Scholar
• Gee JM, Robertson JF, Gutteridge E, Ellis IO, Pinder SE, Rubini M et al. (2005). Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer. Endocr Relat Cancer 12 (Suppl. 1): S99–S111.
  Article CAS Google Scholar
• Green S, Issemann I, Sheer E . (1988). A versatile in vivo and in vitro eukaryotic expression vector for protein engineering. Nucl Acids Res 16: 369.
  Article CAS Google Scholar
• Grippo PJ, Sandgren EP . (2000). Highly invasive transitional cell carcinoma of the bladder in a simian virus 40 T-antigen transgenic mouse model. Am J Pathol 157: 805–813.
  Article CAS Google Scholar
• Gunther EJ, Belka GK, Wertheim GB, Wang J, Hartman JL, Boxer RB et al. (2002). A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology. FASEB J 16: 283–292.
  Article CAS Google Scholar
• Gururaj AE, Rayala SK, Vadlamudi RK, Kumar R . (2006). Novel mechanisms of resistance to endocrine therapy: genomic and nongenomic considerations. Clin Cancer Res 12: 1001s–1007s.
  Article CAS Google Scholar
• Gutzman JH, Nikolai SE, Rugowski DE, Watters JJ, Schuler LA . (2005). Prolactin and estrogen enhance the activity of activating protein 1 in breast cancer cells: role of extracellularly regulated kinase 1/2-mediated signals to c-fos. Mol Endocrinol 19: 1765–1778.
  Article CAS Google Scholar
• Hewitt SC, Bocchinfuso WP, Zhai J, Harrell C, Koonce L, Clark J et al. (2002). Lack of ductal development in the absence of functional estrogen receptor alpha delays mammary tumor formation induced by transgenic expression of ErbB2/neu. Cancer Res 62: 2798–2805.
  CAS PubMed Google Scholar
• Holbro T, Civenni G, Hynes NE . (2003). The ErbB receptors and their role in cancer progression. Exp Cell Res 284: 99–110.
  Article CAS Google Scholar
• Humphreys RC, Hennighausen L . (2000). Transforming growth factor alpha and mouse models of human breast cancer. Oncogene 19: 1085–1091.
  Article CAS Google Scholar
• Jacks T, Remington L, Williams BO, Schmitt EM, Halachmi S, Bronson RT et al. (1994). Tumor spectrum analysis in p53-mutant mice. Curr Biol 4: 1–7.
  Article CAS Google Scholar
• Jerry DJ, Kittrell FS, Kuperwasser C, Laucirica R, Dickinson ES, Bonilla PJ et al. (2000). A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development. Oncogene 19: 1052–1058.
  Article CAS Google Scholar
• Kisseberth WC, Brettingen NT, Lohse JK, Sandgren EP . (1999). Ubiquitous expression of marker transgenes in mice and rats. Dev Biol 214: 128–138.
  Article CAS Google Scholar
• Kuperwasser C, Hurlbut GD, Kittrell FS, Dickinson ES, Laucirica R, Medina D et al. (2000). Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice. A model for Li-Fraumeni syndrome. Am J Pathol 157: 2151–2159.
  Article CAS Google Scholar
• Lee S, Mohsin SK, Mao S, Hilsenbeck SG, Medina D, Allred DC . (2006). Hormones, receptors, and growth in hyperplastic enlarged lobular units: early potential precursors of breast cancer. Breast Cancer Res 8: R6.
  Article Google Scholar
• Livak KJ, Schmittgen TD . (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(−Delta Delta C(T)) Method. Methods 25: 402–408.
  Article CAS Google Scholar
• Medina D, Kittrell FS . (2003). p53 function is required for hormone-mediated protection of mouse mammary tumorigenesis. Cancer Res 63: 6140–6143.
  CAS PubMed Google Scholar
• Otten AD, Sanders MM, McKnight GS . (1988). The MMTV LTR promoter is induced by progesterone and dihydrotestosterone but not by estrogen. Mol Endocrinol 2: 143–147.
  Article CAS Google Scholar
• Pfaffl MW, Horgan GW, Dempfle L . (2002). Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30: e36.
  Article Google Scholar
• Pfaffl MW, Tichopad A, Prgomet C, Neuvians TP . (2004). Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BestKeeper – Excel-based tool using pair-wise correlations. Biotechnol Lett 26: 509–515.
  Article CAS Google Scholar
• Pierson-Mullany LK, Skildum A, Faivre E, Lange CA . (2003). Cross-talk between growth factor and progesterone receptor signaling pathways: implications for breast cancer cell growth. Breast Dis 18: 21–31.
  Article CAS Google Scholar
• Robinson GW, McKnight RA, Smith GH, Hennighausen L . (1995). Mammary epithelial cells undergo secretory differentiation in cycling virgins but require pregnancy for the establishment of terminal differentiation. Development 121: 2079–2090.
  CAS PubMed Google Scholar
• Rose-Hellekant TA, Arendt LM, Schroeder MD, Gilchrist K, Sandgren EP, Schuler LA . (2003). Prolactin induces ERalpha-positive and ERalpha-negative mammary cancer in transgenic mice. Oncogene 22: 4664–4674.
  Article CAS Google Scholar
• Rose-Hellekant TA, Gilchrist K, Sandgren EP . (2002). Strain background alters mammary gland lesion phenotype in transforming growth factor-alpha transgenic mice. Am J Pathol 161: 1439–1447.
  Article CAS Google Scholar
• Rose-Hellekant TA, Sandgren EP . (2000). Transforming growth factor alpha- and c-myc-induced mammary carcinogenesis in transgenic mice. Oncogene 19: 1092–1096.
  Article CAS Google Scholar
• Rudland PS, Fernig DG, Smith JA . (1995). Growth factors and their receptors in neoplastic mammary glands. Biomed Pharmacother 49: 389–399.
  Article CAS Google Scholar
• Sandgren EP, Luetteke NC, Palmiter RD, Brinster RL, Lee DC . (1990). Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell 61: 1121–1135.
  Article CAS Google Scholar
• Sandgren EP, Schroeder JA, Qui TH, Palmiter RD, Brinster RL, Lee DC . (1995). Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice. Cancer Res 55: 3915–3927.
  CAS PubMed Google Scholar
• Stoesz SP, Gould MN . (1995). Overexpression of neu-related lipocalin (NRL) in neu-initiated but not ras or chemically initiated rat mammary carcinomas. Oncogene 11: 2233–2241.
  CAS PubMed Google Scholar
• Zhang X, Podsypanina K, Huang S, Mohsin SK, Chamness GC, Hatsell S et al. (2005). Estrogen receptor positivity in mammary tumors of Wnt-1 transgenic mice is influenced by collaborating oncogenic mutations. Oncogene 24: 4220–4231.
  Article CAS Google Scholar