Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR et al. The epidemiology of major depressive disorder: results from the National comorbidity survey replication (NCS-R). JAMA 2003; 289: 3095–3105. Article Google Scholar
Preskorn S, Stanga C, Feighner J, Ross R (eds) Antidepressants: Past, Present and Future. Springer Verlag, Berlin, Heidelburg, New York, 2004 p 242. Book Google Scholar
Rang HD, Dale MM, Ritter JM . Pharmacology. 4th edn. Churchill Livingstone, 1999 p 830. Google Scholar
Schildkraut JJ . The catecholamine hypothesis of affective disorders: a review of supporting evidence. Am J Psychiatry 1965; 122: 509–522. ArticleCAS Google Scholar
Axelrod J, Tomchick R . Enzymatic O-methylation of epinephrine and other catechols. J Biol Chem 1958; 233: 702–705. CASPubMed Google Scholar
Grossman MH, Creveling CR, Breakefield XO . Isolation of the mRNA encoding rat liver catechol-O-methyltransferase. Biochem Biophys Res Commun 1989; 158: 776–782. ArticleCAS Google Scholar
Grossman MH, Emanuel BS, Budarf ML . Chromosomal mapping of the human catechol-O-methyltransferase gene to 22q11.1----q11.2. Genomics 1992; 12: 822–825. ArticleCAS Google Scholar
Badner JA, Gershon ES . Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Mol Psychiatry 2002; 7: 405–411. ArticleCAS Google Scholar
Lundstrom K, Tenhunen J, Tilgmann C, Karhunen T, Panula P, Ulmanen I . Cloning, expression and structure of catechol-O-methyltransferase. Biochim Biophys Acta 1995; 1251: 1–10. ArticleCAS Google Scholar
Tenhunen J, Salminen M, Lundstrom K, Kiviluoto T, Savolainen R, Ulmanen I . Genomic organization of the human catechol O-methyltransferase gene and its expression from two distinct promoters. Eur J Biochem 1994; 223: 1049–1059. ArticleCAS Google Scholar
Weinshilboum RM . Pharmacogenomics: catechol O-methyltransferase to thiopurine S-methyltransferase. Cell Mol Neurobiol 2006; 26: 539–561. ArticleCAS Google Scholar
Weinshilboum RM, Raymond FA . Inheritance of low erythrocyte catechol-o-methyltransferase activity in man. Am J Hum Genet 1977; 29: 125–135. CASPubMedPubMed Central Google Scholar
Scanlon PD, Raymond FA, Weinshilboum RM . Catechol-O-methyltransferase: thermolabile enzyme in erythrocytes of subjects homozygous for allele for low activity. Science 1979; 203: 63–65. ArticleCAS Google Scholar
Spielman RS, Weinshilboum RM . Genetics of red cell COMT activity: analysis of thermal stability and family data. Am J Med Genet 1981; 10: 279–290. ArticleCAS Google Scholar
Lachman HM, Papolos DF, Saito T, Yu YM, Szumlanski CL, Weinshilboum RM . Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 1996; 6: 243–250. ArticleCAS Google Scholar
Craddock N, Owen MJ, O′Donovan MC . The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons. Mol Psychiatry 2006; 11: 446–458. ArticleCAS Google Scholar
Goodman JE, Lavigne JA, Hengstler JG, Tanner B, Helzlsouer KJ, Yager JD . Catechol-O-methyltransferase polymorphism is not associated with ovarian cancer risk. Cancer Epidemiol Biomarkers Prev 2000; 9: 1373–1376. CASPubMed Google Scholar
Millikan RC, Pittman GS, Tse CK, Duell E, Newman B, Savitz D et al. Catechol-O-methyltransferase and breast cancer risk. Carcinogenesis 1998; 19: 1943–1947. ArticleCAS Google Scholar
Thompson PA, Shields PG, Freudenheim JL, Stone A, Vena JE, Marshall JR et al. Genetic polymorphisms in catechol-O-methyltransferase, menopausal status, and breast cancer risk. Cancer Res 1998; 58: 2107–2110. CASPubMed Google Scholar
Ji Y, Olson J, Zhang J, Hildebrandt M, Wang L, Ingle J et al. Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms. Cancer Res 2008; 68: 5997–6005. ArticleCAS Google Scholar
Zhang J, Ji Y, Moon I, Pelleymounter LL, Salavaggione OE, Wu Y et al. Catechol O-methyltransferase pharmacogenomics: human liver genotype-phenotype correlation and proximal promoter studies. Pharmacogenet Genomics 2009; 19: 577–587. ArticleCAS Google Scholar
Shield AJ, Thomae BA, Eckloff BW, Wieben ED, Weinshilboum RM . Human catechol O-methyltransferase genetic variation: gene resequencing and functional characterization of variant allozymes. Mol Psychiatry 2004; 9: 151–160. ArticleCAS Google Scholar
Howland RH . Sequenced Treatment Alternatives to Relieve Depression (STAR*D). Part 2: Study outcomes. J Psychosoc Nurs Ment Health Serv 2008; 46: 21–24. Article Google Scholar
Zisook S, Ganadjian K, Moutier C, Prather R, Rao S . Sequenced Treatment Alternatives to Relieve Depression (STAR*D): lessons learned. J Clin Psychiatry 2008; 69: 1184–1185. Article Google Scholar
Trivedi MH, Rush AJ, Wisniewski SR, Nierenberg AA, Warden D, Ritz L et al. Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice. Am J Psychiatry 2006; 163: 28–40. Article Google Scholar
Mrazek DA, Rush AJ, Biernacka JM, O’Kane DJ, Cunningham JM, Wieben ED et al. SLC6A4 variation and citalopram response. Am J Med Genet B Neuropsychiatr Genet 2008; 150B: 341–351. Article Google Scholar
Stram DO, Haiman CA, Hirschhorn JN, Altshuler D, Kolonel LN, Henderson BE et al. Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study. Hum Hered 2003; 55: 27–36. Article Google Scholar
Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA . Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 2004; 74: 106–120. ArticleCAS Google Scholar
Nackley AG, Shabalina SA, Tchivileva IE, Satterfield K, Korchynskyi O, Makarov SS et al. Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure. Science 2006; 314: 1930–1933. ArticleCAS Google Scholar
Shifman S, Bronstein M, Sternfeld M, Pisante-Shalom A, Lev-Lehman E, Weizman A et al. A highly significant association between a COMT haplotype and schizophrenia. Am J Hum Genet 2002; 71: 1296–1302. ArticleCAS Google Scholar
Peters EJ, Slager SL, Kraft JB, Jenkins GD, Reinalda MS, McGrath PJ et al. Pharmacokinetic genes do not influence response or tolerance to citalopram in the STAR*D sample. PLoS ONE 2008; 3: e1872. Article Google Scholar
Kaakkola S, Gordin A, Mannisto PT . General properties and clinical possibilities of new selective inhibitors of catechol O-methyltransferase. Gen Pharmacol 1994; 25: 813–824. ArticleCAS Google Scholar
Loots GG, Ovcharenko I, Pachter L, Dubchak I, Rubin EM . rVista for comparative sequence-based discovery of functional transcription factor binding sites. Genome Res 2002; 12: 832–839. Article Google Scholar
Loots GG, Locksley RM, Blankespoor CM, Wang ZE, Miller W, Rubin EM et al. Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons. Science 2000; 288: 136–140. ArticleCAS Google Scholar
Grabe N . AliBaba2: context specific identification of transcription factor binding sites. In Silico Biol 2002; 2: S1–15. PubMed Google Scholar
Landschulz WH, Johnson PF, Adashi EY, Graves BJ, McKnight SL . Isolation of a recombinant copy of the gene encoding C/EBP. Genes Dev 1988; 2: 786–800. ArticleCAS Google Scholar
Birkenmeier EH, Gwynn B, Howard S, Jerry J, Gordon JI, Landschulz WH et al. Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein. Genes Dev 1989; 3: 1146–1156. ArticleCAS Google Scholar
Thase ME, Haight BR, Richard N, Rockett CB, Mitton M, Modell JG et al. Remission rates following antidepressant therapy with bupropion or selective serotonin reuptake inhibitors: a meta-analysis of original data from 7 randomized controlled trials. J Clin Psychiatry 2005; 66: 974–981. ArticleCAS Google Scholar
Serretti A, Artioli P . The pharmacogenomics of selective serotonin reuptake inhibitors. Pharmacogenomics J 2004; 4: 233–244. ArticleCAS Google Scholar
Kirchheiner J, Nickchen K, Bauer M, Wong ML, Licinio J, Roots I et al. Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response. Mol Psychiatry 2004; 9: 442–473. ArticleCAS Google Scholar
Kato M, Serretti A . Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder. Mol Psychiatry 2008; 15: 473–500. Article Google Scholar
Peters EJ, Slager SL, Jenkins GD, Reinalda MS, Garriock HA, Shyn SI et al. Resequencing of serotonin-related genes and association of tagging SNPs to citalopram response. Pharmacogenet Genomics 2009; 19: 1–10. ArticleCAS Google Scholar
Szegedi A, Rujescu D, Tadic A, Muller MJ, Kohnen R, Stassen HH et al. The catechol-O-methyltransferase Val108/158Met polymorphism affects short-term treatment response to mirtazapine, but not to paroxetine in major depression. Pharmacogenomics J 2005; 5: 49–53. ArticleCAS Google Scholar
Arias B, Serretti A, Lorenzi C, Gasto C, Catalan R, Fananas L . Analysis of COMT gene (Val 158 Met polymorphism) in the clinical response to SSRIs in depressive patients of European origin. J Affect Disord 2006; 90: 251–256. ArticleCAS Google Scholar
Yoshida K, Higuchi H, Takahashi H, Kamata M, Sato K, Inoue K et al. Influence of the tyrosine hydroxylase val81met polymorphism and catechol-O-methyltransferase val158met polymorphism on the antidepressant effect of milnacipran. Hum Psychopharmacol 2008; 23: 121–128. ArticleCAS Google Scholar
Garriock HA, Kraft JB, Shyn SI, Peters EJ, Yokoyama JS, Jenkins GD et al. A genomewide association study of citalopram response in major depressive disorder. Biol Psychiatry 2010; 67: 133–138. ArticleCAS Google Scholar