Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation (original) (raw)

• Maliszewski, C.R. et al. The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization. J. Immunol. 153, 3574–3583 (1994).
  CAS Google Scholar
• Wang, T.-F. & Guidotti, G. CD39 is an ecto-(Ca2+, Mg 2+)-apyrase. J. Biol. Chem. 271, 9898–9901 (1996).
  Article CAS Google Scholar
• Kaczmarek, E. et al. Identification and characterization of CD39/vascular ATP diphosphohydrolase. J. Biol. Chem. 271, 33116– 33122 (1996).
  Article CAS Google Scholar
• Chadwick, B.P. & Frischauf, A.M. The CD39-like gene family - identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster . Genomics 50, 357– 367 (1998).
  Article CAS Google Scholar
• Fijnheer, R. et al. Stored platelets release nucleotides as inhibitors of platelet function. Thromb. Haemost. 68, 595– 599 (1992).
  Article CAS Google Scholar
• Heyns, A.d.P., Badenhorst, M. & Retief, F.P. ADPase activity of normal and atherosclerotic human aorta intima. Thromb. Haemost. 37, 429– 435 (1977).
  Article CAS Google Scholar
• Coade, S.B. & Pearson, J.D. Metabolism of adenine nucleotides in human blood. Circ. Res. 65, 531– 537 (1989).
  Article CAS Google Scholar
• Zimmermann, H. 5'-nucleotidase: molecular structure and functional aspects. Biochem. J. 285, 345–365 ( 1992).
  Article CAS Google Scholar
• Luthje, J. Origin, metabolism and function of extracellular adenine nucleotides in the blood. Klin. Wochenschr. 67, 317– 27 (1989); erratum: 67, 558 (1989).
  Article CAS Google Scholar
• Fredholm, B.B. et al. Nomenclature and classification of purinoreceptors. Pharmacol. Rev. 46, 143–152 (1994).
  CAS Google Scholar
• Daniel, J.L. et al. Molecular basis for ADP-induced platelet activation I–evidence for three distinct ADP receptors on human platelets. J. Biol. Chem. 273, 2024–2029 ( 1998).
  Article CAS Google Scholar
• Jin, J.G., Daniel, J.L. & Kunapuli, S.P. Molecular basis for ADP-induced platelet activation II - the P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets J. Biol. Chem. 273, 2030–2034 (1998).
  Article CAS Google Scholar
• Dubyak, G.R. & Elmoatassim, C. Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. Am. J. Physiol. 265,C 577–C 606 ( 1993).
  Article CAS Google Scholar
• Motte, S., Communi, D., Pirotton, S. & Boeynaems, J.M. Involvement of multiple receptors in the actions of extracellular ATP: the example of vascular endothelial cells. Int. J. Biochem. Cell Biol. 27, 1–7 (1995 ).
  Article CAS Google Scholar
• Marcus, A.J. & Safier, L.B. Thromboregulation: multicellular modulation of platelet reactivity in hemostasis and thrombosis. FASEB J. 7, 516–22 ( 1993).
  Article CAS Google Scholar
• Robson, S.C. et al. Loss of ATP diphosphohydrolase activity with endothelial cell activation. J. Exp. Med. 185, 153– 163 (1997).
  Article CAS Google Scholar
• Schafer, A.I. Vascular endothelium–in defense of blood fluidity. J. Clin. Invest. 99, 1143–1144 ( 1997).
  Article CAS Google Scholar
• Denis, C. et al. A mouse model of severe von-Willebrand-disease–defects in hemostasis and thrombosis. Proc. Nat. Acad. Sci. USA 95, 9524–9529 (1998).
  Article CAS Google Scholar
• Berger, G., Hartwell, D.Q., Wagner, D.D. P-selectin and platelet clearance. Blood 92, 4446–4452 (1998).
  CAS Google Scholar
• Koyamada, N. et al. Apyrase administration prolongs discordant xenograft survival. Transplant 62, 1739–1743 (1996).
  Article CAS Google Scholar
• Jin, J.G. & Kunapuli S.P. Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation. Proc. Nat. Acad. Sci.USA 95, 8070– 8074 (1998).
  Article CAS Google Scholar
• Bach, F.H. et al. Delayed xenograft rejection. Immunol. Today 17, 379–384 (1996).
  Article CAS Google Scholar
• Siess, W. Molecular mechanisms of platelet activation. Physiol. Rev. 69, 58–178 (1989).
  Article CAS Google Scholar
• Shen, J., Gimbrone, M.A.J., Luscinkas, F.W. & Dewey, C.F.J. Regulation of adenine nucleotide concentration at endothelium-fluid interface by viscous shear flow. Biophys. J. 64, 1323 –1330 (1993).
  Article CAS Google Scholar
• Sun, B., Li, J., Okahara, K. & Kambayashi, J. P2x(1) Purinoceptor in human platelets - molecular cloning and functional characterization after heterologous expression. J. Biol. Chem. 273, 11544–11547 (1998).
  Article CAS Google Scholar
• Weisman, G.A. et al. P2Y nucleotide receptors in the immune system: Signaling by a P2Y(2) receptor in U937 monocytes. Drug Dev. Res. 45, 222–228 (1998).
  Article CAS Google Scholar
• Weilerguettler, H. et al. A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state. J. Clin. Invest. 101 , 1983–1991 (1998).
  Article CAS Google Scholar
• Von Albertini, M. et al. Extracellular ATP and ADP activate transcription factor NF-kappa-B and induce endothelial cell apoptosis. Biochem Biophys Res Commun 248, 822–829 ( 1998).
  Article CAS Google Scholar
• Deguchi H. et al. Adenosine regulates tissue factor expression on endothelial cells. Thromb. Res. 91, 57– 64 (1998).
  Article CAS Google Scholar
• Bakker, W.W. et al. Experimental endotoxemia in pregnancy: in situ glomerular microthrombus formation associated with impaired glomerular adenosine diphosphatase activity. J. Lab. Clin. Med. 114, 531– 537 (1989).
  CAS Google Scholar
• Yang, Z.H. et al. Different interactions of platelets with arterial and venous coronary bypass vessels. Lancet 337, 939 –943 (1991).
  Article CAS Google Scholar
• Candinas, D. et al. Loss of rat glomerular ATP diphosphohydrolase activity during reperfusion injury is associated with oxidative stress reactions. Thromb. Haemost. 76, 807–812 (1996).
  Article CAS Google Scholar
• Gayle R.B. et al. Inhibition of platelet function by recombinant soluble ecto-ADPase/CD39. J. Clin. Invest. 101, 1851– 1859 (1998).
  Article CAS Google Scholar
• Sévigny, J., Levesque, F.P., Grondin, G. & Beaudoin, A.R. Purification of the blood vessel ATP diphosphohydrolase, identification and localization by immunological techniques. Biochim. Biophys. Acta. 1334, 73–88 ( 1997).
  Article Google Scholar
• Baykov, A.A., Evtushenko, O.A. & Avaeva, S.M. A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay. Analyt. Biochem. 171, 266–270 (1988).
  Article CAS Google Scholar
• Bradford, M.M. A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248–254 ( 1976).
  Article CAS Google Scholar
• Liu, M.A. Overview of DNA vaccines. Ann. N.Y. Acad. Sci. 772, 15–20 (1995).
  Article CAS Google Scholar
• Towbin, H., Staehelin, T. & Gordon, J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications. Proc. Nat. Acad. Sci. USA 76, 4350– 4354 (1979).
  Article CAS Google Scholar
• Edelberg, J.M. et al. PDGF mediates cardiac microvascular communication. J. Clin. Invest. 102, 837–843 (1998).
  Article CAS Google Scholar
• Lundin, A., Richardsson A. & Thore, A. Continuous monitoring of ATP-converting reactions by purified firefly luciferase. Anal. Biochem. 75, 611–620 (1976).
  Article CAS Google Scholar
• Beurling-Harbury, C. & Harbury, P.B. Extraction of protein-bound ATP and ADP from human platelets in plasma. Thromb. Haemost. 63, 286–290 ( 1990).
  Article CAS Google Scholar
• Saito, H. et al. Plasma concentration of adenosine during normoxia and moderate hypoxia in humans. Am. J. Resp. Crit. Care Med. 159 , 1014–1018 (1999).
  Article CAS Google Scholar
• Dejana, E., Callioni, A., Quintana, A. & de Gaetano, G. Bleeding time in laboratory animals. II - A comparison of different assay conditions in rats. Thromb. Res. 15, 191 –197 (1979).
  Article CAS Google Scholar
• Johnson, E.N., Brass, L.F. & Funk, C.D. Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase. Proc. Nat. Acad. Sci. USA 95, 3100–3105 (1998).
  Article CAS Google Scholar
• Koyamada, N. et al. Transient complement inhibition plus T-cell immunosuppression induces long-term survival of mouse-to-rat cardiac xenografts. Transplantation 65, 1210–1215 (1998).
  Article CAS Google Scholar