γ-Globulin in Foetal Bovine Sera: Significance in Virology (original) (raw)

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• Published: 20 May 1967

Nature volume 214, pages 805–806 (1967)Cite this article

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Abstract

IT has been generally accepted that the transplacental transfer of maternal antibodies to the foetus normally does not occur in species of Bovidae1–5. Nevertheless, many investigators have noted that pooled foetal bovine sera neutralize certain viruses and that the sera of 1 day old, colostrum-deprived calves occasionally contain γ-globulin. Not infrequently such findings have been attributed to the contamination of foetal serum with adult serum and to unobserved suckling of the newborn. In our investigations with certain bovine viruses we also have noted the appreciable, and apparently specific, virus neutralizing capacity of pooled foetal bovine sera procured from commercial sources. We have therefore examined the occurrence of γ-globulin in individual samples of foetal sera and evaluated the capacity of such sera to neutralize virus.

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Authors and Affiliations

1. School of Public Health, University of California, Naval Biological Laboratory, N.C.S., Oakland, California
   A. J. KNIAZEFF & V. RIMER
2. Hyland Laboratories, Los Angeles, California
   L. GAETA

Authors

1. A. J. KNIAZEFF
2. V. RIMER
3. L. GAETA

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KNIAZEFF, A., RIMER, V. & GAETA, L. _γ_-Globulin in Foetal Bovine Sera: Significance in Virology.Nature 214, 805–806 (1967). https://doi.org/10.1038/214805b0

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• Received: 06 October 1966
• Revised: 12 January 1967
• Issue date: 20 May 1967
• DOI: https://doi.org/10.1038/214805b0

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