Absence of Thymus in a Mouse Mutant (original) (raw)

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• Published: 27 January 1968

Nature volume 217, pages 370–371 (1968)Cite this article

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Abstract

THE mouse mutant “nude” has been described by Flanagan1. It is an autosomal recessive. The homozygotes, nu nu, are hairless and their growth is retarded. More than half die before weaning and none survives for as long as 25 weeks. Other parts of the syndrome were: sulphydryl group deficiency and abnormal keratinization of hair follicles, and necrosis of the liver, associated with Toxoplasma gondii infection. No single primary defect of development responsible for these pleiotropic effects could be suggested.

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Authors and Affiliations

1. Biology Department, University of Strathclyde, Glasgow
   E. M. PANTELOURIS

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1. E. M. PANTELOURIS
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PANTELOURIS, E. Absence of Thymus in a Mouse Mutant.Nature 217, 370–371 (1968). https://doi.org/10.1038/217370a0

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• Received: 22 December 1967
• Issue Date: 27 January 1968
• DOI: https://doi.org/10.1038/217370a0