GABAB-receptor subtypes assemble into functional heteromeric complexes (original) (raw)

• Kerr, D. I. & Ong, J. GABABreceptors. Pharmacol. Ther. 67, 187–246 (1995).
  Article CAS Google Scholar
• Bettler, B., Kaupmann, K. & Bowery, N. G. GABABreceptors: drugs meet clones. Curr. Opin. Neurobiol. 8, 345–350 (1998).
  Article CAS Google Scholar
• Kaupmann, K.et al. Expression cloning of GABABreceptors uncovers similarity to metabotropic glutamate receptors. Nature 386, 239–246 (1997).
  Article ADS CAS Google Scholar
• Kaupmann, K.et al. Human GABABreceptors are differentially expressed and regulate inwardly rectifying K+_ channels. Proc. Natl Acad. Sci. USA(in the press).
• Ward, D. T., Brown, E. M. & Harris, H. W. Disulfide bonds in the extracellular calcium-polyvalent cation-sensing receptor correlate with dimer formation and its response to divalent cations in vitro. J. Biol. Chem. 273, 14476–14483 (1998).
  Article CAS Google Scholar
• Romano, C., Yang, W.- & O'Malley, L. Metabotropic glutamate receptor 5 is a disulfide-linked dimer. J. Biol. Chem. 271, 28612–28616 (1996).
  Article CAS Google Scholar
• Sodickson, D. L. & Bean, B. P. GABABreceptor-activated inwardly rectifying potassium current in dissociated hippocampal CA3 neurons. J. Neurosci. 16, 6374–6385 (1996).
  Article CAS Google Scholar
• Lüscher, C., Jan, L. Y., Stoffel, M., Malenka, R. C. & Nicoll, R. A. Gprotein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons. Neuron 19, 687–695 (1997).
  Article Google Scholar
• Slesinger, P. A., Stoffel, M., Jan, Y. N. & Jan, L. Y. Defective γ-amino butyric acid type B receptor-activated inwardly rectifying K+ currents in cerebellar granule cells isolated from weaver and GIRK2 null mutant mice. Proc. Natl Acad Sci. USA 94, 12210–12217 (1997).
  Article ADS CAS Google Scholar
• Inoue, M., Matsuo, T. & Ogata, N. Characterization of pre- and postsynaptic actions of (−)-baclofen in the guinea-pig hippocampus in vitro. Br. J. Pharmacol. 84, 843–851 (1985).
  Article CAS Google Scholar
• Uezono, Y.et al. Activation of inwardly rectifying K+ channels by GABABreceptors expressed in Xenopus oocytes. Neuroreport 9, 583–587 (1998).
  Article CAS Google Scholar
• Couve, A.et al. Intracellular retention of recombinant GABABreceptors. J. Biol. Chem. 273, 26361–26367 (1998).
  Article CAS Google Scholar
• Hill, D. R., Bowery, N. G. & Hudson, A. L. Inhibition of GABABreceptor binding by guanyl nucleotides. J. Neurochem. 42, 652–657 (1984).
  Article CAS Google Scholar
• Morris, S. J., Beatty, D. M. & Chronwall, B. M. GABABR1a/R1b-type receptor antisense deoxynucleotide treatment of melanotropes blocks chronic GABABreceptor inhibition of high-voltage-activated Ca+ channels. J. Neurochem. 71, 1329–1332 (1998).
  Article CAS Google Scholar
• Kenakin, T. Differences between natural and recombinant G-protein coupled receptor systems with varying receptor/G-protein stoichiometry. Trends Pharmacol. Sci. 18, 456–464 (1997).
  Article CAS Google Scholar
• McLatchie, L. M.et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 393, 333–339 (1998).
  Article ADS CAS Google Scholar
• Dwyer, N. D., Troemel, E. R., Sengupta, P. & Bargmann, C. I. Odorant receptor localization to olfactory cilia is mediated by ODR-4, a novel membrane-associated protein. Cell 93, 455–466 (1998).
  Article CAS Google Scholar
• Bischoff, S., Barhanin, J., Bettler, B., Mulle, C. & Heinemann, S. Spatial distribution of kainate receptor subunit mRNA in the mouse basal ganglia and ventral mesencephalon. J. Comp. Neurol. 379, 541–562 (1997).
  Article CAS Google Scholar
• Malitschek, B.et al. Developmental changes in agonist affinity at GABABR1 receptor variants in rat brain. Mol. Cell. Neurosci. 12, 56–64 (1998).
  Article CAS Google Scholar
• Olpe, H.-R.et al. CGP 35348: a centrally active blocker of GABABreceptors. Eur. J. Pharmacol. 187, 27–38 (1990).
  Article CAS Google Scholar
• Shigemoto, R.et al. Target-cell-specific concentration of a metabotropic glutamate receptor in the presynaptic active zone. Nature 381, 523–525 (1996).
  Article ADS CAS Google Scholar
• Wischmeyer, E.et al. Subunit interactions in the assembly of neuronal Kir3.0 inwardly rectifying K+ channels. Mol. Cell. Neurosci. 9, 194–206 (1997).
  Article CAS Google Scholar
• Mosbacher, J.et al. P2Y receptor subtypes differentially couple to inwardly rectifying potassium channels. FEBS Lett. 436, 104–110 (1998).
  Article CAS Google Scholar
• von Heijne, G. Anew method for predicting signal sequence cleavage sites. Nucleic Acids Res. 14, 4683–4690 (1986).
  Article CAS Google Scholar
• O'Hara, P. J.et al. The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins. Neuron 11, 41–52 (1993).
  Article CAS Google Scholar