Spontaneous voltage fluctuations in retinal cones and bipolar cells (original) (raw)

Nature volume 256, pages 661–662 (1975)Cite this article

Abstract

TRIFONOV1 and others have suggested that vertebrate rods and cones release transmitter continuously in the dark and that the effect of light is to suppress this release by making the inside of the cell more negative. On this hypothesis the bipolar cells, which receive information from cones, should be electrically noisy in the dark, because of random fluctuations in the release of cone transmitter, and relatively quiet in the light when the release of transmitter is suppressed2.

This is a preview of subscription content, access via your institution

Access options

Subscribe to this journal

Receive 51 print issues and online access

$199.00 per year

only $3.90 per issue

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Additional access options:

Similar content being viewed by others

References

  1. Trifonov, Y. A., Biofizika (in Russian), 13, 809–817 (1968).
    CAS PubMed Google Scholar
  2. Falk, G., and Fatt, P., in Handbook of Sensory Physiology, VII/1 (edit. by Dartnall, H. J. A.), 200–244, (Springer, New York, 1972).
    Google Scholar
  3. Werblin, F. S., and Dowling, J. E., J. Neurophysiol., 32, 339–355 (1969).
    Article CAS Google Scholar
  4. Kaneko, A., J. Physiol., Lond., 207, 623–633 (1970).
    Article CAS Google Scholar
  5. Baylor, D. A., Fuortes, M. G. F., and O'Bryan, P. M., J. Physiol., Lond., 214, 265–294 (1971).
    Article CAS Google Scholar
  6. Richter, A., and Simon, E. J., J. Physiol., Lond., 248, 317–334 (1975).
    Article CAS Google Scholar
  7. Katz, B., and Miledi, R., J. Physiol., Lond., 224, 665–699 (1972).
    Article CAS Google Scholar
  8. Baylor, D. A., and Hodgkin, A. L., J. Physiol., Lond., 234, 163–198 (1973).
    Article CAS Google Scholar
  9. Fain, G. L., Science, 187, 838–841 (1975).
    Article CAS ADS Google Scholar
  10. Schwartz, E. A., J. Physiol., Lond., 246, 617–638 (1975).
    Article CAS Google Scholar
  11. Fuortes, M. G. F., and Yeandle, S., J. gen. Physiol., 47, 443–463 (1964).
    Article CAS Google Scholar
  12. Baylor, D. A., Hodgkin, A. L., and Lamb, T. D., J. Physiol., Lond., 242, 685–727 (1974).
    Article CAS Google Scholar

Download references

Author information

Authors and Affiliations

  1. Physiological Laboratory University of Cambridge, Cambridge, CB2 3EG, UK
    E. J. SIMON, T. D. LAMB & A. L. HODGKIN

Authors

  1. E. J. SIMON
    You can also search for this author inPubMed Google Scholar
  2. T. D. LAMB
    You can also search for this author inPubMed Google Scholar
  3. A. L. HODGKIN
    You can also search for this author inPubMed Google Scholar

Rights and permissions

About this article

Cite this article

SIMON, E., LAMB, T. & HODGKIN, A. Spontaneous voltage fluctuations in retinal cones and bipolar cells.Nature 256, 661–662 (1975). https://doi.org/10.1038/256661a0

Download citation