Unusual physical organization of the Halobacterium genome (original) (raw)

Nature volume 295, pages 384–389 (1982)Cite this article

Abstract

The genomes of the extremely halophilic bacteria, Halobacterium halobium and Halobacterium volcanii, contain many repeated sequences. These sequences comprise many families, seem to be highly mobile and are arranged in both clustered and dispersed fashions within these genomes. At least some repeated sequences are more strongly conserved between the two species than are unique sequence DNAs.

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References

  1. Woese, C. R. Scient. Am. 244(6), 94–106 (1981).
    Article ADS Google Scholar
  2. Fox, G. E. et al. Science 209, 457–463 (1980).
    Article ADS CAS Google Scholar
  3. Doolittle, W. F. Trends biochem. Sci. 5, 146–149 (1980).
    Article CAS Google Scholar
  4. Bayley, S. T. & Mortem, R. A. CRC crit. Rev. Microbiol. 6, 151–205 (1978).
    Article CAS Google Scholar
  5. Mitchell, R. M., Loeblich, L. A., Klotz, L. C. & Loeblich, A. R. III Science 204, 1082–1084 (1979).
    Article ADS CAS Google Scholar
  6. Searcy, D. G. & Doyle, E. K. Int. J. Syst. Bact. 25, 286–289 (1975).
    Article CAS Google Scholar
  7. Moore, R. L. & McCarthy, B. J. J. Bact. 99, 248–254 (1969).
    CAS PubMed Google Scholar
  8. Moore, R. L. & McCarthy, B. J. J. Bact. 99, 255–262 (1969).
    CAS PubMed Google Scholar
  9. Weidinger, G., Klotz, G. & Goebel, W. Plasmid 2, 377–386 (1979).
    Article CAS Google Scholar
  10. Pfeifer, F., Weidinger, G. & Goebel, W. J. Bact. 145, 375–381 (1981).
    CAS PubMed Google Scholar
  11. Rigby, P. W. J., Dieckmann, M., Rhodes, C. & Berg, P. J. molec. Biol. 113, 237–251 (1977).
    Article CAS Google Scholar
  12. Southern, E. M. J. molec. Biol. 98, 503–517 (1975).
    Article CAS Google Scholar
  13. Bedbrook, J., Jones, J. & Flavell, R. Cold Spring Harb. Symp. quant. Biol. 45, 755–760 (1981).
    Article CAS Google Scholar
  14. Scheller, R. H. et al. J. molec. Biol. 149, 15–39 (1981).
    Article CAS Google Scholar
  15. Graf, H. Biochim. biophys. Acta 564, 225–234 (1979).
    Article CAS Google Scholar
  16. Norgard, M. V., Keem, K. & Monahan, J. J. Gene 3, 279–292 (1978).
    Article CAS Google Scholar
  17. Birnboim, H. C. & Doly, J. Nucleic Acids Res. 7, 1513–1523 (1979).
    Article CAS Google Scholar
  18. Hofman, J. D., Lau, R. H. & Doolittle, W. F. Nucleic Acids Res. 7, 1331–1334 (1979).
    Article Google Scholar
  19. Jeffreys, A. J. & Flavell, R. A. Cell 12, 429–439 (1977).
    Article CAS Google Scholar

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Authors and Affiliations

  1. Department of Biochemistry, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada, B3H 4H7
    Carmen Sapienza & W. Ford Doolittle

Authors

  1. Carmen Sapienza
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  2. W. Ford Doolittle
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Sapienza, C., Doolittle, W. Unusual physical organization of the Halobacterium genome.Nature 295, 384–389 (1982). https://doi.org/10.1038/295384a0

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