Association of an S1 nuclease-sensitive structure with short direct repeats 5′ of Drosophila heat shock genes (original) (raw)
- Letter
- Published: 11 August 1983
Nature volume 304, pages 555–557 (1983)Cite this article
- 96 Accesses
- 175 Citations
- Metrics details
Abstract
The potential for a DNA molecule to assume different tertiary structures has been suggested as a possible determinant of transcriptional regulation in eukaryotes1,2. Such forms include cruciforms3,4 transitions from B to Z DNA in the same molecule2,5 and short unpaired stretches of DNA in an alternating copolymer6. All such structures contain regions which are preferentially sensitive to S1 nuclease4–6. We report here an additional class of S1 nuclease sensitive sites associated with short direct repeats of DNA found in the 5′ flanking regions of certain Drosophila melanogaster heat shock genes.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Additional access options:
Similar content being viewed by others
References
- Larsen, A. & Weintraub, H. Cell 29, 609–622 (1982).
Article CAS Google Scholar - Nordheim, A., Lafer, E. M., Peck, L. J., Wang, J. C. & Stollar, B. D. Cell 31, 309–318 (1982).
Article CAS Google Scholar - Lilley, D. M. J. Proc. natn. Acad. Sci. U.S.A. 77, 6468–6472 (1980).
Article ADS CAS Google Scholar - Panayotatos, N. & Wells, R. D. Nature 289, 466–470 (1981).
Article ADS CAS Google Scholar - Klysik, J., Stirdivant, S. M., Larson, J. E., Hart, P. A. & Wells, R. D. Nature 290, 672–677 (1981).
Article ADS CAS Google Scholar - Hentschel, C. C. Nature 295, 714–716 (1982).
Article ADS CAS Google Scholar - Pelham, H. R. B. Cell 30, 517–528 (1982).
Article CAS Google Scholar - Pelham, H. R. B. & Bienz, M. EMBO J. 1, 1473–1477 (1982).
Article CAS Google Scholar - Mirault, M.-E., Southgate, R. & Delwart, E. EMBO J. 1, 1279–1286 (1982).
Article CAS Google Scholar - Ish-Horowicz, D., Pinchin, S. M., Schedl, P., Artavanis-Tsakonas, S. & Mirault, M.-E. Cell 18, 1351–1358 (1979).
Article CAS Google Scholar - Southern, E. M. J. molec. Biol. 98, 503–517 (1975).
Article CAS Google Scholar - Karch, F., Török, I. & Tissieres, A. J. molec. Biol. 148, 219–230 (1981).
Article CAS Google Scholar - Ingolia, T. D. & Craig, E. A. Nucleic Acids Res. 9, 1627–1641.
- Golding, C. R. & Russell, W. C. Nucleic Acids Res. 11, 21–36 (1983).
Article Google Scholar - Bienz, M. & Pelham, H. R. B. EMBO J. 1, 1583–1588 (1982).
Article CAS Google Scholar - Pelham, H. R. B. & Lewis, M. J. in Gene Expression (eds Hamer, D. & Rosenberg, M) (Liss, New York, in the press).
- Weintraub, H. Cell 32, 1191–1203 (1983).
Article CAS Google Scholar
Author information
Authors and Affiliations
- Laboratory of Molecular Biology, Medical Research Council Centre, Hills Road, Cambridge, CB2 2QH, UK
Hilary A. F. Mace, Hugh R. B. Pelham & Andrew A. Travers
Authors
- Hilary A. F. Mace
You can also search for this author inPubMed Google Scholar - Hugh R. B. Pelham
You can also search for this author inPubMed Google Scholar - Andrew A. Travers
You can also search for this author inPubMed Google Scholar
Rights and permissions
About this article
Cite this article
Mace, H., Pelham, H. & Travers, A. Association of an S1 nuclease-sensitive structure with short direct repeats 5′ of Drosophila heat shock genes.Nature 304, 555–557 (1983). https://doi.org/10.1038/304555a0
- Received: 14 April 1983
- Accepted: 21 June 1983
- Issue Date: 11 August 1983
- DOI: https://doi.org/10.1038/304555a0