Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model (original) (raw)

References

  1. Lefkowitz, R. J., Wessels, M. R. & Stadel, J. M. Curr. Top. Cell. Regul. 17, 205–230 (1980).
    CAS PubMed Google Scholar
  2. Perkins, J. P. Curr. Top. Membranes Transp. 18, 85–108 (1983).
    CAS Google Scholar
  3. Harden, T. K. Pharmac. Rev. 35, 5–32 (1983).
    CAS Google Scholar
  4. Hertel, C. & Perkins, J. P. Molec. cell. Endocr. 37, 245–256 (1984).
    CAS PubMed Google Scholar
  5. Benovic, J. L., Shorr, R. G. L., Caron, M. G. & Lefkowitz, R. J. Biochemistry 23, 4510–4518 (1984).
    Article CAS PubMed Google Scholar
  6. Cubero, A. & Malbon, C. C. J. biol. Chem. 259, 1344–1350 (1984).
    CAS PubMed Google Scholar
  7. Shorr, R. G. L., Lefkowitz, R. J. & Caron, M. G. J. biol. Chem. 256, 5820–5826 (1981).
    CAS PubMed Google Scholar
  8. Shorr, R. G. L., Strohsacker, M. W., Lavin, T. N., Lefkowitz, R. J. & Caron, M. G. J. biol. Chem. 257, 12341–12350 (1982).
    CAS PubMed Google Scholar
  9. Sibley, D. R., Peters, J. R., Nambi, P., Caron, M. G. & Lefkowitz, R. J. Biochem. biophys. Res. Commun. 119, 458–464 (1984).
    CAS PubMed Google Scholar
  10. Codina, J. et al. Adv. Cyclic Nucleotide Res. 17, 111–126 (1984).
    CAS Google Scholar
  11. Gilman, A. G. Cell 36, 577–579 (1984).
    CAS PubMed Google Scholar
  12. Pfeuffer, E., Dreher, R. M., Metzger, H. & Pfeuffer, T. Proc. natn. Acad. Sci. U.S.A. 82, 3086–3090 (1985).
    ADS CAS Google Scholar
  13. Stadel, J. M. & Lefkowitz, R. J. Curr. Top. Membranes Transp. 18, 45–66 (1983).
    CAS Google Scholar
  14. Schramm, M. & Selinger, Z. Science 225, 1350–1356 (1984).
    ADS CAS PubMed Google Scholar
  15. Mukherjee, C., Caron, M. G. & Lefkowitz, R. J. Proc. natn. Acad. Sci. U.S.A. 72, 1945–1949 (1975).
    ADS CAS Google Scholar
  16. Mukherjee, C., Caron, M. G. & Lefkowitz, R. J. Endocrinology 99, 347–357 (1976).
    CAS PubMed Google Scholar
  17. Mickey, J., Tate, R. & Lefkowitz, R. J. J. biol. Chem. 250, 5727–5729 (1975).
    CAS PubMed Google Scholar
  18. Mickey, J. V., Tate, T., Mullikin, D. & Lefkowitz, R. J. Molec. Pharmac. 12, 409–419 (1976).
    CAS Google Scholar
  19. Wessels, M. R., Mullikin, D. & Lefkowitz, R. J. J. biol. Chem. 253, 3371–3373 (1978).
    CAS PubMed Google Scholar
  20. Wessels, M. R., Mullikin, D. & Lefkowitz, R. J. Molec. Pharmac. 16, 10–20 (1979).
    CAS Google Scholar
  21. Shear, M., Insel, P. A., Melmon, K. L. & Coffino, P. J. biol. Chem. 251, 7572–7576 (1976).
    CAS PubMed Google Scholar
  22. Su, Y.-F., Harden, T. K. & Perkins, J. P. J. biol. Chem. 254, 38–41 (1979).
    CAS PubMed Google Scholar
  23. Harden, T. K., Su, Y.-F. & Perkins, J. P. J. Cyclic Nucleotide Res. 5, 99–106 (1979).
    CAS PubMed Google Scholar
  24. Su, Y.-F., Harden, T. K. & Perkins, J. P. J. biol. Chem. 255, 7410–7419 (1980).
    CAS PubMed Google Scholar
  25. Homburger, V. et al. J. biol. Chem. 255, 10436–10444 (1980).
    CAS PubMed Google Scholar
  26. Fishman, P. H., Mallorga, P. & Tallman, J. F. Molec. Pharmac. 20, 310–318 (1981).
    CAS Google Scholar
  27. Green, D. A. & Clark, R. B. J. biol. Chem. 256, 2105–2108 (1981).
    CAS PubMed Google Scholar
  28. Green, D. A., Friedman, J. & Clark, R. B. J. Cyclic Nucleotide Res. 7, 161–172 (1981).
    CAS PubMed Google Scholar
  29. Iyengar, R., Bhat, M. K., Riser, M. E. & Birnbaumer, L. J. biol. Chem. 256, 4810–4815 (1981).
    CAS PubMed Google Scholar
  30. Chuang, D.-M. & Costa, E. Proc. natn. Acad. Sci. U.S.A. 76, 3024–3028 (1979).
    ADS CAS Google Scholar
  31. Chuang, D.-M., Kinnier, W. J., Farber, L. & Costa, E. Molec. Pharmac. 18, 348–355 (1980).
    CAS Google Scholar
  32. Chuang, D.-M. & Costa, E. Neurochem. Res. 4, 777–793 (1979).
    CAS PubMed Google Scholar
  33. Stadel, J. M. et al. J. biol. Chem. 258, 3032–3038 (1983).
    CAS PubMed Google Scholar
  34. Strasser, R. H., Stiles, G. L. & Lefkowitz, R. J. Endocrinology 115, 1392–1400 (1984).
    CAS PubMed Google Scholar
  35. Harden, T. K., Cotton, C. U., Waldo, G. L., Lutton, J. K. & Perkins, J. P. Science 210, 441–443 (1980).
    ADS CAS PubMed Google Scholar
  36. Waldo, G. L., Northup, J. K., Perkins, J. P. & Harden, T. K. J. biol. Chem. 258, 13900–13908 (1983).
    CAS PubMed Google Scholar
  37. Toews, M. L., Waldo, G. L., Harden, T. K. & Perkins, J. P. J. biol. Chem. 259, 11844–11850 (1984).
    CAS PubMed Google Scholar
  38. Frederich, R. C. Jr, Waldo, G. L., Harden, T. K. & Perkins, J. P. J. Cyclic Nucleotide Prot. Phosphor. Res. 9, 103–118 (1983).
    CAS Google Scholar
  39. Hertel, C., Staehelin, M. & Perkins, J. P. J. Cyclic Nucleotide Prot. Phosphor. Res. 9, 119–128 (1983).
    CAS Google Scholar
  40. Hertel, C., Muller, P., Portenier, M. & Staehelin, M. Biochem. J. 216, 669–674 (1983).
    CAS PubMed PubMed Central Google Scholar
  41. Staehelin, M., Simons, P., Jaegg, K. & Wigger, N. J. biol. Chem. 258, 3496–3502 (1983).
    CAS PubMed Google Scholar
  42. Staehelin, M. & Hertel, C. J. receptor Res. 3, 35–43 (1983).
    CAS Google Scholar
  43. Pittman, R. N. & Molinoff, P. B. J. Cyclic Nucleotide Res. 6, 421–435 (1980).
    CAS PubMed Google Scholar
  44. Pittman, R. N. & Molinoff, P. B. Molec. Pharmac. 24, 398–408 (1983).
    CAS Google Scholar
  45. Toews, M. L., Harden, T. K. & Perkins, J. P. Proc. natn. Acad. Sci. U.S.A. 80, 3553–3557 (1983).
    ADS CAS Google Scholar
  46. Toews, M. L. & Perkins, J. P. J. biol. Chem. 259, 2227–2235 (1984).
    CAS PubMed Google Scholar
  47. Insel, P. A., Mahan, L. C., Motulsky, H. J., Stoolman, L. M. & Koachman, A. M. J. biol. Chem. 258, 13597–13605 (1983).
    CAS PubMed Google Scholar
  48. Hoyer, D., Reynolds, E. E. & Molinoff, P. B. Molec. Pharmac. 25, 209–218 (1984).
    CAS Google Scholar
  49. Morishima, I., Thompson, W. J., Robison, G. A. & Strada, S. J. Molec. Pharmac. 18, 370–378 (1980).
    CAS Google Scholar
  50. Doss, R. C., Perkins, J. P. & Harden, T. K. J. biol. Chem. 256, 12281–12286 (1981).
    CAS PubMed Google Scholar
  51. Su, Y.-F., Cubeddu, L. X. & Perkins, J. P. J. Cyclic Nucleotide Res. 2, 257–270 (1976).
    CAS PubMed Google Scholar
  52. Mahan, L. C., Koachman, A. M. & Insel, P. A. Proc. natn. Acad. Sci. U.S.A. 82, 129–133 (1985).
    ADS CAS Google Scholar
  53. Strulovici, B., Stadel, J. M. & Lefkowitz, R. J. J. biol. Chem. 258, 6410–6414 (1983).
    CAS PubMed Google Scholar
  54. Clark, R. B., Friedman, J., Prashad, N. & Ruoho, A. E. J. Cyclic Nucleotide Prot. Phosphor. Res. 10, 97–119 (1985).
    CAS Google Scholar
  55. Strasser, R. H. & Lefkowitz, R. J. J. biol. Chem. 260, 4561–4564 (1985).
    CAS PubMed Google Scholar
  56. Kassis, S. & Fishman, P. H. Proc. natn. Acad. Sci. U.S.A. 81, 6686–6690 (1984).
    ADS CAS Google Scholar
  57. Anderson, W. B. & Jaworski, C. J. J. biol. Chem. 254, 4596–4601 (1979).
    CAS PubMed Google Scholar
  58. Salomon, Y., Ezra, E. & Amir-Zaltsman, Y. Adv. Cyclic Nucleotide Res. 14, 101–109 (1981).
    CAS PubMed Google Scholar
  59. Hunzicker-Dunn, M., Derda, D., Jungmann, R. A. & Birnbaumer, L. Endocrinology 104, 1785–1793 (1979).
    CAS PubMed Google Scholar
  60. Sibley, D. R., Strasser, R. H., Caron, M. G. & Lefkowitz, R. J. J. biol. Chem. 260, 3883–3886 (1985).
    CAS PubMed Google Scholar
  61. Pastan, I. H. & Willingham, M. C. A. Rev. Physiol. 43, 239–250 (1981).
    CAS Google Scholar
  62. Strader, C. D., Sibley, D. R. & Lefkowitz, R. J. Life Sci. 35, 1601–1610 (1984).
    CAS PubMed Google Scholar
  63. Johnson, G. L., Wolfe, B. B., Harden, T. K., Molinoff, P. B. & Perkins, J. P. J. biol. Chem. 253, 1472–1480 (1978).
    CAS PubMed Google Scholar
  64. de Vellis, J. & Brooker, G. Science 186, 1221–1223 (1974).
    ADS CAS Google Scholar
  65. Terasaki, W. L. et al. Adv. Cyclic Nucleotide Res. 9, 33–52 (1978).
    CAS PubMed Google Scholar
  66. Nichols, G. A. & Brooker, G. J. Cyclic Nucleotide Res. 5, 435–447 (1979).
    Google Scholar
  67. Nichols, G. A. & Brooker, G. J. biol. Chem. 255, 23–26 (1980).
    Google Scholar
  68. Barovsky, K., Pedone, C. & Brooker, G. J. Cyclic Nucleotide Prot. Phosphor. Res. 9, 181–189 (1983).
    CAS Google Scholar
  69. Kassis, S. & Fishman, P. H. J. biol. Chem. 257, 5312–5318 (1982).
    CAS PubMed Google Scholar
  70. Garrity, M. J., Andreasen, T. J., Storm, D. R. & Robertson, R. P. J. biol. Chem. 258, 8692–8697 (1983).
    CAS PubMed Google Scholar
  71. Kirchik, H. J., Iyengar, R. & Birnbaumer, L. Endocrinology 113, 1638–1646 (1983).
    Google Scholar
  72. Rich, K. A. et al. J. biol. Chem. 259, 7893–7901 (1984).
    CAS PubMed Google Scholar
  73. Hoffman, B. B., Mullikin-Kilpatrick, D. & Lefkowitz, R. J. J. Cyclic Nucleotide Res. 5, 355–366 (1979).
    CAS PubMed Google Scholar
  74. Simpson, I. A. & Pfeuffer, T. Eur. J. Biochem. 111, 111–116 (1980).
    CAS PubMed Google Scholar
  75. Hudson, T. H. & Johnson, G. L. Molec. Pharmac. 20, 694–703 (1981).
    CAS Google Scholar
  76. Briggs, M. M., Stadel, J. M., Iyengar, R. & Lefkowitz, R. J. Archs Biochem. Biophys. 224, 142–151 (1983).
    CAS Google Scholar
  77. Stadel, J. M. et al. J. biol. Chem. 257, 9242–9245 (1982).
    CAS PubMed Google Scholar
  78. Strulovici, B., Cerione, R. A., Kilpatrick, B. F., Caron, M. G. & Lefkowitz, R. J. Science 225, 837–840 (1984).
    ADS CAS PubMed Google Scholar
  79. Stadel, J. M. et al. Proc. natn. Acad. Sci. U.S.A. 80, 3173–3177 (1983).
    ADS CAS Google Scholar
  80. Sibley, D. R., Peters, J. R., Nambi, P., Caron, M. G. & Lefkowitz, R. J. J. biol. Chem. 259, 9742–9749 (1984).
    CAS PubMed Google Scholar
  81. Nambi, P. et al. J. biol. Chem. 259, 4629–4633 (1984).
    CAS PubMed Google Scholar
  82. Nambi, P., Peters, J. R., Sibley, D. R. & Lefkowitz, R. J. J. biol. Chem. 260, 2165–2171 (1985).
    CAS PubMed Google Scholar
  83. Benovic, J. L. et al. J. biol. Chem. 260, 7094–7101 (1985).
    CAS PubMed Google Scholar
  84. Sibley, D. R., Nambi, P., Peters, J. R. & Lefkowitz, R. J. Biochem. biophys. Res. Commun. 121, 973–979 (1984).
    CAS PubMed Google Scholar
  85. Kelleher, D. J., Pessin, J. E., Ruoho, A. E. & Johnson, G. L. Proc. natn. Acad. Sci. U.S.A. 81, 4316–4320 (1984).
    ADS CAS Google Scholar
  86. Stadel, J. M., De Lean, A., Mullikin-Kilpatrick, D., Sawyer, D. D. & Lefkowitz, R. J. J. Cyclic Nucleotide Res. 7, 37–47 (1981).
    CAS PubMed Google Scholar
  87. Noda, C. et al. J. biol. Chem. 259, 7747–7754 (1984).
    CAS PubMed Google Scholar
  88. Koschel, K. Eur. J. Biochem. 108, 163–169 (1980).
    CAS PubMed Google Scholar
  89. Attramadal, H., Le Gac, F., Jahnsen, T. & Hansson, V. Molec. cell. Endocr. 34, 1–6 (1984).
    CAS PubMed Google Scholar
  90. Leeb-Lundberg, L. M. F. et al. Proc. natn. Acad. Sci. U.S.A. (in the press).
  91. Liebman, P. A. & Sitaramayya, A. Adv. Cyclic Nucleotide Prot. Phosphor. Res. 17, 215–225 (1984).
    CAS Google Scholar
  92. Shichi, H. & Somers, R. L. J. biol. Chem. 253, 7040–7046 (1978).
    CAS PubMed Google Scholar
  93. Somers, R. L. & Klein, D. C. Science 226, 182–184 (1984).
    ADS CAS PubMed Google Scholar
  94. Shichi, H., Yamamoto, K. & Somers, R. L. Vision Res. (in the press).
  95. Engstrom, P. & Hazelbauer, G. L. Cell 20, 165–171 (1980).
    CAS PubMed Google Scholar
  96. De Franco, A. L. & Koshland, D. E. Jr Proc. natn. Acad. Sci. U.S.A. 77, 2429–2434 (1980).
    ADS CAS Google Scholar
  97. Goy, M. F., Springer, M. S. & Adler, J. Proc. natn. Acad. Sci. U.S.A. 74, 4964–4969 (1977).
    ADS CAS Google Scholar

Download references