A unique circadian-rhythm photoreceptor (original) (raw)

Drosophila cryptochromes

Nature volume 404, pages 456–457 (2000)Cite this article

Abstract

Cryptochrome proteins are critical for circadian rhythms, but their function(s) is uncertain. Here we show that a mutation in a cryptochrome (dCRY) from the fruitfly Drosophila blocks an essential photoresponse of circadian rhythms, namely arrhythmicity under constant light conditions. We conclude that dCRY acts as a key photoreceptor for circadian rhythms and that there is probably no other comparable photoreceptor in this species.

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Figure 1: cry b circadian rhythms free-run under intense constant light.

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Authors and Affiliations

  1. Department of Biology, NSF Center for Biological Timing, Brandeis University, Waltham, 02454, Massachusetts, USA
    Patrick Emery, Jeffrey C. Hall & Michael Rosbash
  2. Howard Hughes Medical Institute, Brandeis University, Waltham, 02454, Massachusetts, USA
    Michael Rosbash
  3. Zoologisches Institut, Universität Regensburg, Regensburg, D93040, Germany
    Ralf Stanewsky

Authors

  1. Patrick Emery
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  2. Ralf Stanewsky
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  3. Jeffrey C. Hall
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  4. Michael Rosbash
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Corresponding author

Correspondence toMichael Rosbash.

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Emery, P., Stanewsky, R., Hall, J. et al. A unique circadian-rhythm photoreceptor.Nature 404, 456–457 (2000). https://doi.org/10.1038/35006558

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